Results 81 to 90 of about 710,673 (294)

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

The D coefficient in neutron beta decay in effective field theory

open access: yes, 2009
In this paper we explore the time-reversal-odd triple-correlation coefficient in neutron beta decay, the so-called "D coefficient", using heavy-baryon effective field theory with photon degrees of freedom.
Amsler   +25 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

evaluating the stability of systematic risk in Tehran stock exchange [PDF]

open access: yesتحقیقات مالی, 2007
This study aims at testing the degree of stability for beta coefficient across time, depending on the information available from Tehran bourse. Where beta coefficient was calculated using the market model developed by Sharp on 1963, which applies by ...
رضا تهرانی   +1 more
doaj  

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

open access: yesAging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss   +12 more
wiley   +1 more source

P2.18 IMPACT OF CARDIOVASCULAR RISK FACTORS ON CAROTID STIFFNESS AND CAROTID INTIMA MEDIA THICKNESS – GENDER DIFFERENCES

open access: yesArtery Research, 2015
Background and purpose: Whether the influence of risk factors on carotid stiffness (CS) and carotid intima media thickness (CIMT) is modulated by gender is still unclear.
Maria Loboz-Rudnicka*   +6 more
doaj   +1 more source

Growing Scale-free Small-world Networks with Tunable Assortative Coefficient

open access: yes, 2006
In this paper, we propose a simple rule that generates scale-free small-world networks with tunable assortative coefficient. These networks are constructed by two-stage adding process for each new node.
Albert   +46 more
core   +1 more source

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri   +7 more
wiley   +1 more source

Estimating Income Inequality in China Using Grouped Data and the Generalized Beta Distribution [PDF]

open access: yes
Gini coefficient, generalized beta distribution, urban and rural ...
Chotikapanich, Duangkamon   +2 more
core  

Home - About - Disclaimer - Privacy