Results 141 to 150 of about 772,266 (306)
Global Inequality: Recent Evidence and Trends [PDF]
This paper examines the nature and extent of global and regional income distribution and inequality using the most recent country level data on income distribution drawn from World Bank and UNU-WIDER studies for the period 1993-2000. The methodology used
Chotikapanich, Duangkamon +3 more
core
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Zero-inflated beta distribution applied to word frequency and lexical dispersion in corpus linguistics. [PDF]
Burch B, Egbert J.
europepmc +1 more source
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Kummer Beta -Weibull Geometric Distribution A New Generalization of Beta -Weibull Geometric Distribution [PDF]
A new distribution is defined which is called kummer beta -Weibull geometric (KBWG) distribution. KBWG distribution is considered a new generalization for beta-Weibull geometric distribution. Various properties of KBWG distribution are obtained.
Abdel Wahed, Mohamed Lotfy +1 more
core +1 more source
The Modified Beta Weibull Distribution
A new five-parameter model called the modified beta Weibull probability distribution is being introduced in this paper. This model turnsout to be quite flexible for analyzing positive data and has bathtub andupside down bathtub hazard rate function.Our main objectives are to obtain representations of certain statisticalfunctions and to estimate the ...
openaire +2 more sources
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
The article is devoted to the problems of ideas of the subjects of modern society about the long-term prospects for the development of their life path (the so-called “life trajectories”).
P. V. Konyukhovsky, A. V. Yakovleva
doaj +1 more source

