Results 161 to 170 of about 3,421,347 (332)

Scales matter: regional environment factors affect α diversity but local factors affect β diversity of macroinvertebrates in Thousand Islands Lake catchment area

Ecological Indicators
A more profound comprehension of various facets of biodiversity is essential for advancing sustainable governance of biodiversity and its associated ecosystem services.
Zongwei Lin, Guohao Liu, Kun Guo, Kan Wang, Lishani Wijewardene, Naicheng Wu   +5 more
doaj   +1 more source

single-electron events and 0{\nu}{\beta}{\beta} events in CdZnTe: A Monte Carlo simulation study

, 2017
In neutrinoless double beta (0{\nu}{\beta}{\beta}) decay experiments, the diversity of topological signatures of different particles provides an important tool to distinguish double beta events from background events and reduce background rates.
Cang, Jirong, Cheng, Jianping, Fu, Jianqiang, Li, Tenglin, Liu, Yinong, Ma, Hao, Zeng, Ming, Zeng, Weihe, Zeng, Zhi   +8 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Biodiversity is a cauliflower under the sunlight [PDF]

, 2012
For a long time ecologists have questioned the variations of biodiversity across the latitudinal gradient. Recently it has emerged that the changes in [beta]-diversity are caused simply by changes in the sizes of species pools.
Roberto Gatti Cazzolla
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Species richness and beta-diversity of aquatic macrophytes assemblages in three floodplain tropical lagoons: evaluating the effects of sampling size and depth gradients [PDF]

, 2002
Using aquatic macrophyte data gathered in three lagoons of the Paraná River floodplain we showed a strong effect of sample size on species richness. Incidence-based species richness estimators (Chao 2, jackknife 1, jackknife 2, incidence-based coverage ...
Bini, L., Souza, D., Thomaz, S.
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

The spatial scaling of beta diversity [PDF]

Global Ecology and Biogeography, 2012
Philip S. Barton, Saul A. Cunningham, Adrian D. Manning, Heloise Gibb, David B. Lindenmayer, Raphael K. Didham   +5 more
openaire   +1 more source