Results 141 to 150 of about 7,337,590 (301)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Beta function without ultraviolet divergences

open access: yesJournal of High Energy Physics
In this paper, we construct the beta function in the functorial formulation of two-dimensional quantum field theories (FQFT). A key feature of this approach is the absence of ultraviolet divergences.
Maxim Gritskov, Andrey Losev
doaj   +1 more source

Further results on the beta function and the incomplete beta function

open access: yesApplied Mathematical Sciences, 2013
Fatma Al-Sirehy, Brian Fisher
openaire   +1 more source

Cohomological beta function

open access: yes
Corrected ...
Gamayun, Oleksandr   +2 more
openaire   +2 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

On Extended Beta Function and Related Inequalities

open access: yesMathematics
In this article, we consider a unified generalized version of extended Euler’s Beta function’s integral form a involving Macdonald function in the kernel. Moreover, we establish functional upper and lower bounds for this extended Beta function.
Rakesh K. Parmar   +2 more
doaj   +1 more source

Beta-cell function and insulin sensitivity parameters.

open access: yes, 2014
Beta-cell function and insulin sensitivity parameters.
Hans L. Mooij (285750)   +11 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

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