Results 61 to 70 of about 1,232,344 (309)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

TGF beta 1 attenuates expression of prolactin and IGFBP-1 in decidualized endometrial stromal cells by both SMAD-dependent and SMAD-independent pathways [PDF]

, 2010
Background: Decidualization (differentiation) of the endometrial stromal cells during the secretory phase of the menstrual cycle is essential for successful implantation.
Jones Marius, Philippa T K Saunders, Critchley, Hilary O. D., Kane, N.M., Hilary O D Critchley, Dey, Sudhansu Kumar, Kane Nicole M., Jan J Brosens, Marius Jones, Rodney W Kelly, Philippa T. K. Saunders, Jones, M., Kelly, Rodney W., Kane, Nicole M., Saunders Philippa T. K., Nicole M Kane, Jones, Marius, Brosens Jan J., Brosens, J.J., Kelly, R.W., Saunders, Philippa T. K., Jan J. Brosens, Hilary O. D. Critchley, Saunders, P.T.K., Brosens, Jan J., Saunders, Philippa T. K.; id_orcid, Critchley, H.O.D., Critchley Hilary O. D., Kelly Rodney W., Rodney W. Kelly, Nicole M. Kane   +30 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Vertices of Mather’s beta function, II [PDF]

Ergodic Theory and Dynamical Systems, 2009
AbstractIf theβ-function of a time-periodic Lagrangian on a manifoldMhas a vertex at ak-irrational homology classh, then 2k<dimM, so if dimM=2, thenhis rational.
openaire   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Interleukin-1 beta-Targeted Vaccine Improves Glucose Control and beta-Cell Function in a Diabetic KK-A(y) Mouse Model

, 2016
Interleukin-1 beta (IL-1 beta) has been implicated as a key proinflammatory cytokine involved in the pancreatic islet inflammation of type 2 diabetes mellitus (T2DM).
Jun Zha, Xiao-Lin Yu, Rui-Tian Liu, Xiang-Meng Liu, Zha, Jun, Yu, Xiao-lin, Xiao-Wei Chi, Jie Zhu, Liu, Rui-tian, Dong-Qun Liu, Chi, Xiao-wei, Ji, Hui, Liu, Xiang-meng, Liu, Dong-qun, Hui Ji, Zhu, Jie   +15 more
core   +1 more source

aidenybai/million: v2.4.8-beta.1

, 2023
<ul> <li>Fixes params handling and properly handles all edge cases for block function</li> </ul> <p><strong>Full Changelog</strong>: <a href="https://github.com/aidenybai/million/compare/v2.4.8-beta.0...v2.4.8-
Jason Antwi-Appah, Luca Cataldo, 38elements, Danilo Woznica, Énio Carlos, Cody Miller, 波比小金刚, Tobiloba Adedeji, Andrew N, Harsh Agarwal, Pringles, Felippe Regazio, Daniel S. Katz, Will, Eli Turner, Ikko Eltociear Ashimine, Xuanbo Cheng, Fabian Cook, Ademílson F. Tonato, Guillaume Comte, poteboy, Tom Lienard, Jiachi Liu, Aiden Bai, Josh Gillies, Sukka, Giri Madhan, Nathan Cai, Rocktim   +28 more
core   +1 more source

Some inequalities involving two generalized beta functions in n variables

Journal of Inequalities and Applications, 2021
The beta and gamma functions have recently seen several developments and various extensions because of their nice properties and interesting applications. The contribution of this paper falls within this framework.
Mustapha Raïssouli, Salma I. El-Soubhy
doaj   +1 more source

BRANE TILINGS: THE NSVZ BETA FUNCTION [PDF]

International Journal of Modern Physics A, 2010
In honor of Misha Shifman's 60th birthday this note will start with one of Misha's many contributions, the famous NSVZ beta function, and study how it affects the construction of Brane Tilings. The main features of Brane Tilings for 3+1 dimensions SCFT's are reviewed and the generalization to 2+1 dimensional SCFT's is discussed.
openaire   +1 more source