Results 111 to 120 of about 89,617 (292)

Minimal model for membrane oscillations in the pancreatic beta-cell

Biophysical Journal, 1983
Following the experimental findings of Atwater et al. (In Biochemistry Biophysics of the Pancreatic-beta-Cell, George Thieme Verlag, New York, 100-107), we have formulated a mathematical model for ionic and electrical events that take place in pancreatic-beta-cells.
Chay, T.R., Keizer, J.
openaire   +2 more sources

GABAergic synapse properties may explain genetic variation in hippocampal network oscillations in mice

Frontiers in Cellular Neuroscience, 2010
Cognitive ability and the properties of brain oscillation are highly heritable in humans. Genetic variation underlying oscillatory activity might give rise to differences in cognition and behavior. How genetic diversity translates into altered properties
Tim S Heistek, Jaap Timmerman, Sabine Spijker, Arjen B Brussaard, Huibert D Mansvelder   +4 more
doaj   +1 more source

Characterization of an Injectable Poly(vinyl alcohol)‐gelatin Hydrogel for Growth Factor Delivery in an Orthopedic Application

Advanced Healthcare Materials, EarlyView.
This work introduces photo‐crosslinkable tyraminated poly(vinyl alcohol)‐gelatin (PVA‐GT) hydrogels as tunable injectable platforms for tissue engineering and growth factor delivery applications. This schematic illustrates the two developed hydrogel formulations and the experimental workflow used to evaluate their physico‐chemical properties in vitro ...
Alessia Longoni, Gretel S. Major, Sam Arnold, Samuel Tomkins, Eugenia Spessot, Scott Loeffler, Kieran Lau, Richard Tan, Jessica Harte, Roslyn Kemp, Tess Reynolds, Jelena Rnjak‐Kovacina, Gary J. Hooper, Tim B. F. Woodfield, David C. Kieser, Khoon S. Lim   +15 more
wiley   +1 more source

Functional interaction of abnormal beta and gamma oscillations on bradykinesia in parkinsonian rats

Brain Research Bulletin
Bradykinesia, a debilitating symptom characterized by impaired movement initiation and reduced speed in Parkinson’s disease (PD), is associated with abnormal oscillatory activity in the motor cortex-basal ganglia circuit.
Xinxin Jiang, Jian Yang, Zirui Wang, Jun Jia, Gang Wang   +4 more
doaj   +1 more source

Paracrine Factor Local Gradient‐Generating System for Engineering Perfusable Vascularized Hepatocyte Tissues with Perfusion‐Induced Proliferation

Advanced Healthcare Materials, EarlyView.
A paracrine factor local gradient (PFLG)‐generating system enables microvessel penetration across 3D hepatocyte tissues. The resulting vascularized constructs recapitulate hepatic sinusoidal hepatocyte—endothelial contact architecture and enhance hepatic functions in vitro.
Yen‐Hsiang Huang, Tadahiro Yamashita, Ryo Sudo   +2 more
wiley   +1 more source

Engineering Extracellular Vesicle Production Through Magnetic Ion Channel Activation for Bone Regeneration

Advanced Healthcare Materials, EarlyView.
Magnetic Ion Channel Activation (MICA) enables remote stimulation of mechanosensitive ion channels using functionalised magnetic nanoparticles, enhancing extracellular vesicle (EV) biogenesis is pre‐osteoblasts. MICA desrived EVs exhibit typical nano‐vesicular characteristics but display superior pro‐osteogeneic activity, promoting mesenchymal stem ...
Afeesh Rajan Unnithan, Kenny Man, Kritika, Lee A. Gethings, Christopher J. Hughes, Alicia Keenan, Liam Heaney, Sophie C. Cox, Owen G. Davies, Alicia J. El Haj   +9 more
wiley   +1 more source

Minimal Schemes for Large Neutrino Mixings with Inverted Hierarchy

, 2002
Existing oscillation data point to nonzero neutrino masses with large mixings. We analyze the generic features of the neutrino Majorana mass matrix with inverted hierarchy and construct realistic {\it minimal schemes} for the neutrino mass matrix that ...
Aalseth, Ahmad, Ahmad, Ahmad, Ahn, Altarelli, Apollonio, Apollonio, Athanassopoulos, Bahcall, Bandyopadhyay, Barbieri, Barger, Barger, Barger, Barger, Barger, Bazarko, Boehm, Boehm, Bonn, Brahmachari, Brahmachari, Chang, Cheng, Creninelli, Duane A. Dicus, Eisenstein, Elgaroy, Elliott, Fargion, Fargion, Feruglio, Feruglio, Fodor, Fodor, Fogli, Fogli, Frampton, Frampton, Frampton, Frigerio, Fujii, Fukuda, Gell-Mann, Gonzalez-Garcia, Haba, Hambye, Hong-Jian He, Jarlskog, John N. Ng, Klapdor-Kleingrothaus, Klapdor-Kleingrothaus, Klapdor-Kleingrothaus, Koide, Koide, Krastev, Ma, Minakata, Ohlsson, Osipowicz, Pascoli, Pascoli, Petcov, Shafi, Toshito, Wang, Weiler, Weinberg, Wojcicki, Wolfenstein, Xing, Yanagida, Zee, Zee   +74 more
core   +5 more sources

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

Advanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram, Vanessa Arnold, Maik Wolfram‐Schauerte, Anastassiya Moskalchuk, Caroline Trust, Marie Vontz, Mona Scheurenbrand, Vijayasarathy Sampath‐Kumar, Sogand Ahari, Carlos Romero‐Nieto, Lisa Sevenich   +10 more
wiley   +1 more source

Contribution of parvalbumin and somatostatin-expressing GABAergic neurons to slow oscillations and the balance in beta-gamma oscillations across cortical layers

Frontiers in Neural Circuits, 2015
Cortical interneurons are classified into several subtypes that contribute to cortical oscillatory activity. Parvalbumin (PV)-expressing cells, a type of inhibitory interneuron, are involved in the gamma oscillations of local field potentials (LFPs ...
Toshinobu eKuki, Kazuyuki eFujihara, Kazuyuki eFujihara, Kazuyuki eFujihara, Hideki eMiwa, Hideki eMiwa, Nobuaki eTamamaki, Yuchio eYanagawa, Yuchio eYanagawa, Hajime eMushiake, Hajime eMushiake   +10 more
doaj   +1 more source

Supramolecular Engineering of Fluid Pressure in Filamentous Hybrid Double Network Hydrogels for 3D Chondrocyte Culture

Advanced Healthcare Materials, EarlyView.
Inspired by the water‐rich and interconnected biopolymer networks of native load‐bearing tissues, we disclose a connectable design for a hybrid filamentous supramolecular and covalent double network hydrogel generated through in situ photopolymerization.
Ciqing Tong, Ying Chen, Merel L. Janssen, Isabel Sariol, Joeri A. J. Wondergem, Marijn van den Brink, Mertcan Özel, Rob G. H. H. Nelissen, Ingrid Meulenbelt, Doris Heinrich, Yolande F. M. Ramos, Roxanne E. Kieltyka   +11 more
wiley   +1 more source