Results 41 to 50 of about 4,044,085 (243)

Bayesian Inference for the Beta-Weibull Distribution with Applications to Cancer and Under-nutrition Data

open access: yesJournal of Statistical Theory and Applications (JSTA)
The Weibull probability distribution is known to model data from many application areas such as health science, biological science, engineering, finance, economy and education.
Fekade Getabil Habtewold   +2 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Pediatric kidney transplant recipients are at an increased risk for dysbiosis

open access: yesFrontiers in Microbiology
IntroductionThis study aimed to compare the gut microbiota composition in pediatric kidney transplant (KTx) recipient with that of healthy children.MethodsThis cross-sectional observational study included 30 pediatric KTx recipients aged between 7 and 21
Gizem Yılmaz   +5 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Rain: A New Concurrent Process-Oriented Programming Language [PDF]

open access: yes, 2006
This paper details the design of a new concurrent process-oriented programming language, Rain. The language borrows heavily from occam-p and C++ to create a new language based on process-oriented programming, marrying channel-based communication, a clear
Brown, Neil
core  

Web-Based Library Information System at SDN 2 Cerme Kidul

open access: yesJurnal Informatika dan Multimedia
The library transaction process at SDN 2 Cerme Kidul is carried out by utilizing data from this web-based application. Library operations, including membership procedures, borrowing, and returning books, are managed through this application. This website
Rizki Marthanugraha
doaj   +1 more source

pwrEWAS: a user-friendly tool for comprehensive power estimation for epigenome wide association studies (EWAS)

open access: yesBMC Bioinformatics, 2019
Background When designing an epigenome-wide association study (EWAS) to investigate the relationship between DNA methylation (DNAm) and some exposure(s) or phenotype(s), it is critically important to assess the sample size needed to detect a hypothesized
Stefan Graw   +3 more
doaj   +1 more source

Object-oriented programming in the BETA programming language. [PDF]

open access: yes, 1993
This is a book on object-oriented programming and the BETA programming language. Object-oriented programming originated with the Simula languages developed at the Norwegian Computing Center, Oslo, in the 1960s. The first Simula language, Simula I, was intended for writing simulation programs.
Madsen, Ole Lehrmann; id_orcid 0000-0001-7221-142X   +2 more
openaire  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

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