Results 151 to 160 of about 1,051,766 (308)
ABSTRACT Administration of memantine, an antagonist of the N‐methyl‐ d‐aspartate receptor, prevents Ca2+ overload and dehydration of red blood cells (RBCs) in patients with sickle cell disease (SCD). The objectives of the 1‐year dose‐escalation Phase IIa/IIb Memantine trial (MeMAGEN – NCT 03247218) with 17 SCD patients who were under stable ...
Ariel Koren +7 more
wiley +1 more source
GlutathioneS-transferase gene polymorphism: Relation to cardiac iron overload in Egyptian patients with Beta Thalassemia Major [PDF]
Galila M. Mokhtar +6 more
openalex +1 more source
Abstract Chronic red blood cell (RBC) transfusion sustains patients with diverse hematologic disorders, but repeated transfusion leads to iron overload and alloimmunization. Reducing transfusion burden requires identifying donor units that circulate more effectively after storage, yet determinants of this variability remain incompletely defined.
James C. Zimring +13 more
wiley +1 more source
Erythropoiesis in health and disease: Distinguishing defective and ineffective erythropoiesis
Abstract Erythropoiesis is a finely regulated process ensuring continuous red blood cell production to maintain oxygen delivery. Disruptions in this process give rise to defective erythropoiesis, characterized by impaired lineage commitment and progenitor development, and ineffective erythropoiesis (IE), marked by expansion of erythroid progenitors ...
Sara El Hoss +3 more
wiley +1 more source
Protective Effects of Selenium in Patients with Beta-Thalassemia Major [PDF]
ajand aboutalebi +6 more
openalex +1 more source
ABSTRACT Background and Aims Thalassemia is a hereditary hematological condition which interferes with the production of hemoglobin (Hb). Patients with thalassemia require regular blood transfusion, which makes them highly susceptible to pathogens, and especially viral pathogens.
Fatemeh Askari +5 more
wiley +1 more source
Effect of booklet and combined method on parents' awareness of children with β-thalassemia major disorder [PDF]
OBJECTIVE: To assess the effects of booklet and combining methods (lecture, video, etc.) on parents' awareness of children with beta-thalassemia major disorder.
Hasanpour-Dehkordi, A. +1 more
core
The Role of Viral and Bacterial Infections in the Etiology of Behçet's Disease
Bacterial and viral pathogens may play a key role in Behçet's disease (BD) pathogenesis by triggering autoimmunity, molecular mimicry, or microbiome disruption. These infectious agents could initiate inflammatory pathways, contributing to BD's diverse clinical manifestations.
Mohsen Moghoofei +4 more
wiley +1 more source
Haleama Al Sabbah,1 Sarah Khan,1 Abdallah Hamadna,2 Lamia Abu Ghazaleh,2 Anwar Dudin,2 Bashar Adnan Karmi3 1College of Natural and Health Sciences, Zayed University, Dubai, UAE; 2Faculty of Medicine, An-Najah National University, Nablus, Palestine ...
Al Sabbah H +5 more
doaj

