Machine Learning‐Based Detection of HbS and HbC Carriers in the UK General Population
eJHaem, Volume 6, Issue 6, December 2025.ABSTRACT Background Haemoglobin S (HbS) and C (HbC) are the most important sickling variants on the African continent, imposing major health burdens. Early detection of carrier status is crucial but often hindered by resource limitations. Objectives To develop machine learning (ML) models to accurately classify HbS and HbC carriers using readily ...
Frederik Christensen +7 more
wiley +1 more source
Effect of booklet and combined method on parents' awareness of children with β-thalassemia major disorder [PDF]
, 2008 OBJECTIVE: To assess the effects of booklet and combining methods (lecture, video, etc.) on parents' awareness of children with beta-thalassemia major disorder.
Hasanpour-Dehkordi, A. +1 more
core
eJHaem, Volume 6, Issue 6, December 2025.ABSTRACT Introduction Treatment with luspatercept may improve transfusion requirements in transfusion‐dependent thalassemia (TDT), but the improved erythroid maturation in the bone marrow influences body iron distribution. Case Report We report on sequential organ iron measurements in a TDT patient under luspatercept treatment.
Matthias Bleeke +6 more
wiley +1 more source
Reduction of Oxidative Stress and Storage Lesions (RCSL) in Red Blood Cells: Analysis of Ascorbic Acid (AA), N-Acetylcysteine amide (AD4), and Serotonin (5-HT) [PDF]
, 2018 Oxidative stress is a common occurrence in red blood cell (RBC) storage in blood banks throughout the world. Typically RBC units stored under routine standard protocol (stored in SAGM-CPD additive solution) can only be kept up to forty-two days for ...
Gadiraju, Shanmuka
core +1 more source
Molecular Nutrition &Food Research, Volume 69, Issue 24, December 2025.This graphical abstract provides a comparative overview of the mechanisms by which Arthrospira platensis and Chlorella vulgaris exert their effects. It highlights significant differences in their biological pathways, molecular interactions, and physiological effects, providing a clear visual summary.
Alexandra Lacurezeanu +1 more
wiley +1 more source
Conformational lock and thermal inactivation kinetics of Euphorbia amine oxidase [PDF]
The kinetics of thermal inactivation of copper-containing amine oxidase from euphorbia latex (ELAO) were studied in a 100-mM sodium phosphate buffer, pH 7, using cadavarine as the substrate.
امانی, مجتبی +6 more
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Is Hemoglobin Variant Analysis Helpful in the Diagnostic Work-up of Patients Revealing Microcytic Erythrocytosis on Complete Blood Count? [PDF]
, 2015 Introduction: Microcytic erythrocytosis is an abnormal CBC (complete blood count) finding that is under-recognized, poorly understood, and consequently under-utilized in patient care. It is characterized by decreased MCV and increased RBC count.
Dulau-Florea, Alina +3 more
core +1 more source
Bridging the Gaps in Thalassemia Care in Sri Lanka: Challenges and Way Forward
Public Health Challenges, Volume 4, Issue 4, December 2025.ABSTRACT Thalassemia is the most common monogenic disease reported in Sri Lanka and has been a major health issue for decades. Although thalassemia major is preventable, there are about 60–80 births reported annually across the country. In Sri Lanka, the majority of them are managed at government hospitals, and healthcare facilities are provided free ...
L. H. M. R. L. Ambillapitiya +7 more
wiley +1 more source
Is there an association of giardiasis with beta-thalassemia minor? [PDF]
, 2010 Beta–thalassemia minor is a symptomless carrier state of a hemoglobinopathy which predisposes to bacterial infections. We report three cases presenting with giardiasis, a parasitic infection of gastrointestinal tract caused by Giardia lamblia.
Jafri, Wasim +2 more
core +1 more source
Rapid and simultaneous typing of hemoglobin S, hemoglobin C, and seven Mediterranean beta-thalassemia mutations by covalent reverse dot-blot analysis: application to prenatal diagnosis in Sicily [PDF]
, 1993 Aurelio Maggio +5 more
openalex +1 more source