Results 161 to 170 of about 45,973 (258)

Organic Transistor‐Based Biosensors for Viral RNA Detection and Variant Monitoring: From SARS‐CoV‐2 to Effective Management of Future Pandemics

Advanced Sensor Research, Volume 4, Issue 6, June 2025.
A novel approach for direct sensing of viral RNA is proposed, allowing PCR‐free detection of viral RNA from genomic material, and variants screening by discrimination of polymorphic amplicons. The device is a cost‐effective, user‐friendly platform suitable for both mass screening kits and as a laboratory tool for an optimized management of resources ...
Stefano Lai, Roberto Cusano, Alessandra Scano, Giorgio Fotia, Annalisa Bonfiglio   +4 more
wiley   +1 more source

COVID-19 y la pandemia global causada por un nuevo coronavirus

Universidad y Salud, 2020
Introducción: COVID-19 es una enfermedad respiratoria inédita que se reportó inicialmente como una neumonía atípica en diciembre de 2019. SARS-CoV-2, agente etiológico de esta patología, probablemente originado a partir de un virus de murciélago.
Mario Fernando Benavides-Rosero
doaj   +1 more source

Identification of potential SARS‐CoV‐2 genomic regions representing hallmarks for adaptation to different hosts

iMetaOmics, Volume 2, Issue 2, June 2025.
The k‐mer‐based pipeline, namely the Pathogen Origin Recognition Tool using Enriched K‐mers (PORT‐EK) identifies genomic regions enriched in the respective hosts after the comparison of multi‐genomes of isolates between different host species. The enriched k‐mer counts, which may serve as a potential marker, enable the classification and prediction of ...
Janusz Wiśniewski, Heng‐Chang Chen
wiley   +1 more source

The effect of early-stage public health policies in the transmission of COVID-19 for South American countries

Revista Panamericana de Salud Pública, 2020
Objectives. The analysis of transmission dynamics is crucial to determine whether mitigation or suppression measures reduce the spread of coronavirus disease 2019 (COVID-19). This study sought to estimate the basic (R0) and time-varying (Rt) reproduction
Bryan Valcarcel, Jose L. Avilez, J. Smith Torres-Roman, Julio A. Poterico, Janina Bazalar-Palacios, Carlo La Vecchia   +5 more
doaj   +1 more source

The SARS-coronavirus-host interactome [PDF]

, 2011
Coronaviruses (CoVs) are important human and animal pathogens that induce fatal respiratory, gastrointestinal and neurological disease. The outbreak of the severe acute respiratory syndrome (SARS) in 2002/2003 has demonstrated human vulnerability to ...
Brunn, Albrecht von, Carbajo-Lozoya, Javier, Dall'Armi, Ekatarina von, Ditt, Vanessa, Drosten, Christian, Friedel, Caroline C., Haas, Juergen G., Herrler, Georg, Herzog, Petra, Hilgenfeld, Rolf, Kallies, Stefan, Kuri, Thomas, Kögl, Manfred, Müller, Marcel A., Niemeyer, Daniela, Pfefferle, Susanne, Pumpor, Ksenia, Pöhlmann, Stefan, Schwarz, Frank, Schwegmann-Wessels, Christel, Schöpf, Julia, Steffen, Imke, Stellberger, Thorsten, Thiel, Heinz-Jürgen, Thiel, Volker, Weber, Friedemann, Zimmer, Ralf, Züst, Roland   +27 more
core   +1 more source

Land Use Change and Infectious Disease Emergence

Reviews of Geophysics, Volume 63, Issue 2, June 2025.
Abstract Major infectious diseases threatening human health are transmitted to people from animals or by arthropod vectors such as insects. In recent decades, disease outbreaks have become more common, especially in tropical regions, including new and emerging infections that were previously undetected or unknown. Even though there is growing awareness
M. Cristina Rulli, Paolo D’Odorico, Nikolas Galli, Reju S. John, Renata L. Muylaert, Monia Santini, David T. S. Hayman   +6 more
wiley   +1 more source

Performance of Subgenomic RT‐PCR for Predicting SARS‐CoV‐2 Infectivity Compared to Genomic RT‐PCR and Culture Isolation

Journal of Medical Virology, Volume 97, Issue 5, May 2025.
ABSTRACT SARS‐CoV‐2 clinical samples can be detected as positive for a long period of time using real‐time RT‐PCR, even when patients are no longer infectious. Viral culture is the gold standard for assessing a patient's infectivity, but it is a time‐consuming technique and lacks sensitivity. SARS‐CoV‐2 subgenomic RNA (sgRNA) detection has been used as
Célia Sentis, Delphine Parraud, Geneviève Billaud, Martine Valette, Maude Bouscambert‐Duchamp, Bruno Lina, Florence Morfin, Alexandre Gaymard   +7 more
wiley   +1 more source

Patterns of Isoform Variation for N Gene Subgenomic mRNAs in Betacoronavirus Transcriptomes

Viruses
The nucleocapsid (N) protein is the most expressed protein in later stages of SARS-CoV-2 infection with several important functions. It is translated from a subgenomic mRNA (sgmRNA) formed by template switching during transcription. A recently described translation initiation site (TIS) with a CTG codon in the leader sequence (TIS-L) is out of frame ...
James J. Kelley, Andrey Grigoriev
openaire   +3 more sources

The glycosaminoglycan-binding chemokine fragment CXCL9(74–103) reduces inflammation and tissue damage in mouse models of coronavirus infection

Frontiers in Immunology
IntroductionPulmonary diseases represent a significant burden to patients and the healthcare system and are one of the leading causes of mortality worldwide.
Vivian Louise Soares Oliveira, Vivian Louise Soares Oliveira, Celso Martins Queiroz-Junior, Delphine Hoorelbeke, Felipe Rocha da Silva Santos, Ian de Meira Chaves, Mauro Martins Teixeira, Remo de Castro Russo, Paul Proost, Vivian Vasconcelos Costa, Sofie Struyf, Flávio Almeida Amaral   +11 more
doaj   +1 more source

Genome sequences of human coronavirus OC43 and NL63, associated with respiratory infections in Kilifi, Kenya [PDF]

, 2019
Coding-complete genomes of two human coronavirus OC43 strains and one NL63 strain were obtained by metagenomic sequencing of clinical samples collected in 2017 and 2018 in Kilifi, Kenya.
Adema, Irene, Agoti, Charles N., de Laurent, Zaydah R., Kamau, Everlyn, Luka, Martha M., Nokes, D. James   +5 more
core   +2 more sources