Results 141 to 150 of about 37,865 (174)

Broad betacoronavirus neutralization by a stem helix–specific human antibody [PDF]

Science, 2021
Targeting a range of betacoranaviruses In the past 20 years, three highly pathogenic β-coronaviruses have crossed from animals to humans, including the most recent: severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A spike protein that decorates these viruses has an S1 domain that binds host cell receptors and an S2 ...
Martina Beltramello, Dora Pinto, Amalio Telenti   +2 more
exaly   +6 more sources

Recombination and Positive Selection Differentially Shaped the Diversity of Betacoronavirus Subgenera [PDF]

Viruses, 2020
The Betacoronavirus genus of mammal-infecting viruses includes three subgenera (Sarbecovirus, Embecovirus, and Merbecovirus), in which most known human coronaviruses, including SARS-CoV-2, cluster. Coronaviruses are prone to host shifts, with recombination and positive selection possibly contributing to their high zoonotic potential.
Diego Forni, Manuela Sironi, Rachele Cagliani   +2 more
exaly   +5 more sources

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Microtubule depolymerization limits porcine betacoronavirus PHEV replication

Veterinary Microbiology, 2022
Porcine hemagglutinating encephalomyelitis virus (PHEV) is a typical neurotropic betacoronavirus causing digestive disease and/or neurological dysfunction in neonatal pigs. Actin filaments have been identified to implicate in PHEV invasion, but the effects of viral infection on microtubules (MTs) cytoskeleton are unknown.
Qianyu, Zhou, Yungang, Lan, Yifei, Tang, Jiyu, Guan, Kui, Zhao, Feng, Gao, Wenqi, He, Zi, Li   +7 more
openaire   +2 more sources

First Molecular Evidence for Bat Betacoronavirus in Mindanao

Philippine Journal of Science, 2019
Coronaviruses (CoVs) are common agents of respiratory and gastrointestinal tract infections but are also considered as important emerging infectious disease (EID) agents that have led to global epidemics of severe respiratory disease. Human CoV EIDs have been proposed to have originated from bat CoVs (BtCoV).
Tampon, Nikki Vanesa, Rabaya, Ysabela Marie, Malbog, Kameela Monique, Burgos, Sammer, Bacus, Michael, Libre, Kemuel, Valila, Agape Shelley, Achondo, Marion John Michael, Siarot Onggo, Lowela, E. Murao, Lyre Anni   +9 more
openaire   +2 more sources

A Biosafety Level 2 Mouse Model for Studying Betacoronavirus-Induced Acute Lung Damage and Systemic Manifestations

Journal of Virology, 2021
Cristina Guatimosim, Ricardo Durães-Carvalho, Vivian V Costa   +2 more
exaly  

Inhibition of Human Respiratory Influenza A Virus and Human Betacoronavirus-1 by the Blend of Double-Standardized Extracts of Aronia melanocarpa (Michx.) Elliot and Sambucus nigra L.

Pharmaceuticals, 2022
Marta Sochocka, Beata Orzechowska, Michał Ochnik   +2 more
exaly  

A Universal Design of Betacoronavirus Vaccines against COVID-19, MERS, and SARS

Cell, 2020
Gary Wong, Yuan Yuan, Mi Yang
exaly  

Conserved Molecular Signatures in the Spike, Nucleocapsid, and Polymerase Proteins Specific for the Genus Betacoronavirus and Its Different Subgenera

Genes, 2022
Radhey Gupta, Bijendra Khadka, Gupta Radhey S   +2 more
exaly  

RNA structure-altering mutations underlying positive selection on Spike protein reveal novel putative signatures to trace crossing host-species barriers in Betacoronavirus

RNA Biology, 2022
Juan CARLOS Gallego-Gómez, Clara Isabel Bermudez Santana, Alexis Felipe Rojas Cruz   +2 more
exaly  

Intestinal Tropism of a Betacoronavirus ( Merbecovirus ) in Nathusius’s Pipistrelle Bat ( Pipistrellus nathusii ), Its Natural Host

Journal of Virology, 2023
Thijs Kuiken, Bart L Haagmans, Lineke Begeman   +2 more
exaly