Results 111 to 120 of about 3,379 (229)

Development and in vitro evaluation of mucoadhesive microsphere carriers for intranasal delivery of betahistine dihydrochloride [PDF]

open access: yes, 2013
The aim of the present work was to formulate and evaluate betahistine-loaded chitosan microspheres intended for nasal delivery with focus on their mucoadhesive properties.
Bissera Pilicheva   +3 more
core  

The evaluation of ozone and betahistine in the treatment of tinnitus

open access: yes, 2013
The aim of the study is to evaluate the effectiveness of ozone and betahistine treatments in the treatment of tinnitus. Sixty-eight patients were enrolled in this randomized, prospective controlled study.
Sonmez, Onur   +9 more
core   +1 more source

Betahistine: targeting on vascular wall aging [PDF]

open access: yes, 2019
Betahistine are routine drug in neurological practice, which is used to correct vertigo. The clinical efficacy of this drug can be caused not only by neuro-, but also by endotheliotropic action.
Sernov, L. N.   +8 more
core  

A 12-week study on the effects of betahistine (an H₃ antagonist/H₁ agonist) on cognitive functions in schizophrenia patients treated with olanzapine.

open access: yesExperimental and clinical psychopharmacology
Evidence on betahistine for cognitive impairment in schizophrenia is limited. This study evaluated its feasibility, safety, and preliminary efficacy to lay the groundwork for future randomized controlled trials.
Hong-Yu Wang   +11 more
semanticscholar   +1 more source

Reducing olanzapine-induced weight gain side-effect by using betahistine: a study in the rat model

open access: yes, 2012
Olanzapine is effective at treating multiple domains of schizophrenia symptoms. However, it induces serious metabolic side effects. Antipsychotic drug’s antagonistic affinity to histamine H1 receptors has been identified as a main contributor for weight ...
Jiamei Lian (19586263)   +3 more
core  

Comparative responses of the carotid and vertebral arterial systems of rhesus monkeys to betahistine.

open access: yes, 1978
A newly developed photoelectric method was used in 5 rhesus monkeys to measure the mean transit time of blood through the carotid and vertebral arteries, together with measurement of the blood flow through the tissues of the fronto-parietal area supplied
T Sato   +6 more
core   +1 more source

Forced Degradation Studies of Oral Thin Film of Betahistine Dihydrochloride

open access: yesInternational Journal of Drug Delivery Technology
The present study aimed to evaluate the stability profile of Betahistine Dihydrochloride in its pure active pharmaceutical ingredient (API) form and as an Oral Thin Film (OTF) formulation through forced degradation studies under various stress conditions.
Rumita Kumawat, M. Bharkatiya
semanticscholar   +1 more source

A modified method for obtaining betahistine hydrochloride

open access: yes, 1997
The aim of this work was to synthesize betahistine hydrochloride of a satisfactory purity in the highest possible yield. The synthesis consisted of four steps; condensation of paraformaldehyde and 2-methylpyridine yielding 2-(2-pyridyl)ethanol (2) in a ...
Kandeač J.   +6 more
core  

Comparable efficacy and tolerability between twice daily and three times daily betahistine for Meniere's disease

open access: yes, 2009
Conclusion. Betahistine at oral doses of 16 mg tid and 24 mg bid provides similar efficacy and tolerability in the treatment of vertigo in patients with Meniere's disease. Objective.
Ganança, Fernando Freitas [UNIFESP]   +2 more
core   +1 more source

Effects of Betahistine and of its metabolites on vestibular sensory organs

open access: yes, 2001
Betahistine is widely used in the treatment of peripheral and central vestibular disorders. Till now the anti-vertigo effect of the drug was though to be mainly due to an action of betahistine on inner ear or cerebral microcirculation or on some ...
GUTH P. S   +7 more
core  

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