Results 11 to 20 of about 3,379 (229)
Betahistine exerts a dose-dependent effect on cochlear stria vascularis blood flow in guinea pigs in vivo. [PDF]
PLoS ONE, 2012 ObjectiveBetahistine is a histamine H(1)-receptor agonist and H(3)-receptor antagonist that is administered to treat Menière's disease. Despite widespread use, its pharmacological mode of action has not been entirely elucidated.
Fritz Ihler +5 more
doaj +3 more sources
Frontiers in Neurology, 2023 IntroductionBetahistine is widely used for the treatment of various vestibular disorders. However, the approved oral administration route and maximum daily dose are evidently not effective in clinical trials, possibly due to a major first-pass metabolism
Melissa Antons +15 more
doaj +2 more sources
Effects of Betahistine on the Development of Vestibular Compensation after Unilateral Labyrinthectomy in Rats [PDF]
Brain Sciences, 2021 Background: Vestibular compensation (VC) after unilateral labyrinthectomy (UL) consists of the initial and late processes. These processes can be evaluated based on the decline in the frequency of spontaneous nystagmus (SN) and the number of MK801 ...
Junya Fukuda +8 more
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Expert Consensus on Betahistine Mesylate in the Treatment of Vertigo [PDF]
Zhongguo quanke yixue, 2023 In order to standardize scientific drug use in vertigo, the Vertigo Committee of the Chinese Medical Education Association established an expert group to form Expert Consensus on Betahistine Mesylate in the Treatment of Vertigo after repeated discussion ...
The Vertigo Committee of the Chinese Medical Education Association
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Effective management of peripheral vertigo due to benign paroxysmal positional vertigo with betahistine, in the real-world setting: an expert survey with ENT specialists in India [PDF]
International Journal of Research in Medical SciencesBackground: Benign paroxysmal positional vertigo (BPPV) commonly causes peripheral vertigo and is treated with canalith repositioning maneuvers (CRM). Yet, a subset of patients continues to experience vertigo called residual dizziness after undergoing ...
Akash Juneja, R. Bhargava
semanticscholar +2 more sources
Laryngoscope Investigative OtolaryngologyObjective Betahistine is a partial H1 receptor agonist and a potent H3 receptor antagonist commonly used for the treatment of MD and peripheral vertigo.
Ilana Yellin +2 more
doaj +2 more sources
Neuropsychiatric Disease and Treatment, 2018 Tian-ju Wan,1 Yi-Chuan Yu,1 Xiao-gang Zhao,1 Ping Tang,1 Yong-shu Gong2 1Department of Emergency, Yongchuan Hospital of Chongqing Medical University, Chongqing, China; 2Department of Pediatrics, Yongchuan Hospital of Chongqing Medical University ...
Wan TJ, Yu YC, Zhao XG, Tang P, Gong YS
doaj +1 more source
Betahistine in the treatment of peripheral vertigo: an evidence-based review
The Egyptian Journal of OtolaryngologyBackground Vertigo is a common presenting symptom in clinical practice, predominantly of vestibular etiology, and often medicated with betahistine, despite the lack of knowledge concerning its mechanism of action. This paper’s objective was to review the
Bárbara Silva Gameiro +6 more
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World Journal of Otorhinolaryngology-Head and Neck SurgeryObjective Epley maneuver is the most effective treatment for benign paroxysmal positional vertigo (BPPV). Betahistine has been shown to be effective in treating BPPV.
Renad Alsolamy +2 more
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Acta Oto-Laryngologica, 2023 Background Diabetes is associated with inner ear dysfunction. Furthermore, C57BL/6J mice fed high fat diet (HFD), a model for insulin resistance and diabetes, develop endolymphatic hydrops (EH).
Annki Pålbrink +3 more
semanticscholar +3 more sources