Results 101 to 110 of about 2,336,278 (343)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Search for physics beyond the standard model in high-mass diphoton events from proton-proton collisions at $\sqrt{s} =$ 13 TeV [PDF]

open access: yes, 2018
A search for physics beyond the standard model is performed using a sample of high-mass diphoton events produced in proton-proton collisions at $\sqrt{s} = $ 13 TeV.
A. Sirunyan   +499 more
semanticscholar   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

Threshold resummation for dark-matter production at the LHC

open access: yesJournal of High Energy Physics, 2019
We derive precision predictions for the production of dark-matter particles recoiling against a jet with large transverse momentum at the LHC. The dark-matter fermions are described within a simplified model and couple to the Standard Model via a vector ...
M. Krämer   +3 more
doaj   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

In search of a UV completion of the standard model — 378,000 models that don’t work

open access: yesJournal of High Energy Physics, 2018
Asymptotically safe extensions of the Standard Model have been searched for by adding vector-like fermions charged under the Standard Model gauge group and having Yukawa-like interactions with new scalar fields.
D. Barducci   +4 more
doaj   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

The Standard Model of Particle Physics and What Lies Beyond: A View from the Bridge

open access: yesCondensed Matter
The standard models of particle physics and of cosmology have been enormously successful in correlating a large amount of data. However, there are missing pieces and we are still far from what the ultimate model may look like. We give a broad perspective
Pran Nath
doaj   +1 more source

Families from supergroups and predictions for leptonic CP violation

open access: yesJournal of High Energy Physics, 2017
As was shown in 1984 by Caneschi, Farrar, and Schwimmer, decomposing representations of the supergroup SU(M |N ), can give interesting anomaly-free sets of fermion representations of SU(M ) × SU(N ) × U(1).
S. M. Barr, Heng-Yu Chen
doaj   +1 more source

Same sign trilepton as signature of charged Higgs in two Higgs doublet model

open access: yesJournal of High Energy Physics, 2022
We explored the prospect of looking for a fermiophobic charged Higgs (H ±) via the same sign trilepton signal at the LHC. A fermiophobic scenario appears in the type-I two Higgs doublet model where the coupling of the H ± with the Standard Model fermions
Tanmoy Mondal, Prasenjit Sanyal
doaj   +1 more source

Home - About - Disclaimer - Privacy