Results 111 to 120 of about 4,208,806 (276)
, 2018 We discuss the status of the Standard Model (SM): the principles; the Lagrangian; the problems; open questions and the ways beyond. Then we consider possible physics beyond the SM: New symmetries (Gauge, SUSY); New particles (gauge, axion, superpartners); New dimensions (extra, large, compact, etc) or a New Paradigm (strings, branes, gravity).
openaire +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Simultaneous search for extra light and heavy Higgs bosons via cascade decays
Journal of High Energy Physics, 2017 Models with extended Higgs sectors can contain several additional Higgs states, heavier or lighter than the SM Higgs boson. The couplings of lighter extra states to SM particles can be strongly reduced, leading to small cross sections for their direct ...
Ulrich Ellwanger +1 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Robustness of dark matter constraints and interplay with collider searches for New Physics
Journal of High Energy Physics, 2017 We study the implications of dark matter searches, together with collider constraints, on the phenomenological MSSM with neutralino dark matter and focus on the consequences of the related uncertainties in some detail. We consider, inter alia, the latest
A. Arbey +3 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Dark matter casts light on the early Universe
Journal of High Energy Physics, 2018 We show how knowledge of the cold dark matter (CDM) density can be used, in conjunction with measurements of the parameters of a scenario for beyond the Standard Model (BSM) physics, to provide information about the evolution of the Universe before Big ...
A. Arbey +3 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Journal of High Energy Physics, 2017 It is well known that the annihilation of Majorana dark matter into fermions is helicity suppressed. Here, we point out that the underlying mechanism is a subtle combination of two distinct effects, and we present a comprehensive analysis of how the ...
Torsten Bringmann +3 more
doaj +1 more source
The Higgs boson beyond Standard Model.
, 2012 We will review the status of the Higgs boson beyond Standard Model. This proceeding will be focused on the experimental and theoretical status of the Higgs boson in the Composite Higgs models. In particular we will discuss implications on the beyond Standard Model (BSM) Higgs coming from the observed excess at $125$ GeV.
openaire +3 more sources