Results 111 to 120 of about 1,076,028 (306)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Detecting dark matter with Aharonov-Bohm
Journal of High Energy Physics, 2019 While the evidence for dark matter continues to grow, the nature of dark matter remains a mystery. A dark U(1) D gauge theory can have a small kinetic mixing with the visible photon which provides a portal to the dark sector.
John Terning, Christopher B. Verhaaren
doaj +1 more source
Beyond the Standard Model [PDF]
, 2010 A brief overview of the current status of theories for physics beyond the Standard Model.
Lykken, Joseph D, Lykken, Joseph D.
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Baryogenesis, dark matter, and flavor structure in non-thermal moduli cosmology
Journal of High Energy Physics, 2019 The appearance of scalar/moduli fields in the early universe, as motivated by string theory, naturally leads to non-thermal “moduli cosmology”. Such cosmology provides a consistent framework where the generation of radiation, baryons, and dark matter can
Mu-Chun Chen, Volodymyr Takhistov
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
, 2012 In these lectures we briefly cover some of the main lines of research in particle physics beyond the Standard ...
Pomarol, A
core +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Beyond the Standard Model [PDF]
, 1997 These lectures constitute a short course in `Beyond the Standard Model' for students of experimental particle physics. I discuss the general ideas which guide the construction of models of physics beyond the Standard Model. The central principle, the one
Yosef Nir +3 more
core +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source