Results 111 to 120 of about 932,507 (267)

SEARCHING FOR NEW PHYSICS BEYOND THE STANDARD MODEL IN ELECTRIC DIPOLE MOMENT [PDF]

, 2012
Takeshi Fukuyama
openalex   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Beyond the Standard Model

, 1996
Gian F. Giudice
openalex   +2 more sources

Beyond the Standard Model with HAWC

, 2023
P. Harding, A. Albert, Ruben Jose Alfaro, César Álvarez, Alexis Andres, Juan Carlos Arteaga Velázquez, D. Avila Rojas, H. A. Ayala Solares, Rishi Babu, Ernesto Belmont-Moreno, T. Capistrán, Sohyoun Yun, A. Carramiñana, Fernanda Carreon-Gonzalez, U. Cotti, J. Cotzomi, S. Coutinõ de León, E. De la Fuente, Davide Depaoli, Cederik León de León, R. Díaz Hernández, J. C. Díaz–Vélez, Brenda Dingus, Mora Durocher, M. A. DuVernois, K. Engel, María Catalina Espinoza Hernández, Kwok Lung Fan, Ke Fang, N. Fraija, J. A. García-González, F. Garfias, Hazal Goksu, M. M. González, J. A. Goodman, Sam J Groetsch, J. P. Harding, Sergio Hernández Cadena, Ian Herzog, J. A. Hinton, B. Hona, Dezhi Huang, F. Hueyotl‐Zahuantitla, P. Hüntemeyer, A. Iriarte, Vikas Joshi, S. Kaufmann, D. Kieda, A. Lara, J. S. H. Lee, William H. Lee, H. León Vargas, J. Linnemann, A. L. Longinotti, G. Luis-Raya, K. Malone, J. Martínez-Castro, J. Matthews, P. Miranda-Romagnoli, Jorge Alexis Montes, Jorge Antonio Morales Soto, M. Mostafá, L. Nellen, M. U. Nisa, R. Noriega-Papaqui, Laura Olivera-Nieto, N. Omodei, Y. Pérez Araujo, Eucario Gonzalo Pérez Pérez, Alvaro Pratts, Chang Dong Rho, D. Rosa‐González, E. Ruiz-Velasco, Humberto Ibarguen Salazar, Daniel Salazar-Gallegos, A. Sandoval, M. Schneider, Georg Schwefer, José Serna-Franco, A. J. Smith, Y. Son, R. W. Springer, O. Tibolla, Kirsten Tollefson, I. Torres, Ramiro Torres Escobedo, Rhiannon M. Turner, F. Ureña-Mena, Enrique Varela, L. Villaseñor, Xiaojie Wang, I. J. Watson, Felix Werner, Kara M. Whitaker, Elijah Job Willox, Hongyi Hongyi Wu, H. Zhou   +96 more
openalex   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Precision calculations in the Higgs sector within and beyond the Standard Model [PDF]

, 2020
Matteo Capozi
openalex   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source