Results 81 to 90 of about 3,618,801 (299)

Genomic landscape and preclinical models of angiosarcoma

Molecular Oncology, EarlyView.
Angiosarcomas are a rare and aggressive cancer with a poor prognosis for patients. The genomic landscape of angiosarcoma can be highly complex and heterogenous; however, recent studies have identified some common features especially within anatomic and molecular subgroups.
Annaleigh Benton, Bozhi Liu, Lauren E. Gartenhaus, Jason A. Hanna   +3 more
wiley   +1 more source

Threshold resummation for dark-matter production at the LHC

Journal of High Energy Physics, 2019
We derive precision predictions for the production of dark-matter particles recoiling against a jet with large transverse momentum at the LHC. The dark-matter fermions are described within a simplified model and couple to the Standard Model via a vector ...
M. Krämer, A. Kulesza, A. Mück, R. Schürmann   +3 more
doaj   +1 more source

Same sign trilepton as signature of charged Higgs in two Higgs doublet model

Journal of High Energy Physics, 2022
We explored the prospect of looking for a fermiophobic charged Higgs (H ±) via the same sign trilepton signal at the LHC. A fermiophobic scenario appears in the type-I two Higgs doublet model where the coupling of the H ± with the Standard Model fermions
Tanmoy Mondal, Prasenjit Sanyal
doaj   +1 more source

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

Molecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam, Salem Chouaib, Mohammad Askandar Iqbal   +2 more
wiley   +1 more source

Hadron collider sensitivity to fat flavourful Z ′s for R K ∗ $$ {R}_{K^{\left(\ast \right)}} $$

Journal of High Energy Physics, 2019
We further investigate the case where new physics in the form of a massive Z ′ particle explains apparent measurements of lepton flavour non-universality in B → K (*) l + l − decays.
B. C. Allanach, Tyler Corbett, Matthew J. Dolan, Tevong You   +3 more
doaj   +1 more source

Unraveling epigenetic heterogeneity across gastrointestinal adenocarcinomas through a standardized analytical framework

Molecular Oncology, EarlyView.
This study shows that patients with gastrointestinal adenocarcinomas can be stratified into six distinct subtypes based on genome‐scale DNA methylation profiling. This stratification, achieved using a robust analytical framework, aligns with established tumor characteristics and holds potential to support prognostication.
Rita Pinto, Hege Marie Vedeld, Guro Elisabeth Lind, Marine Jeanmougin   +3 more
wiley   +1 more source

NanoCMSer: a consensus molecular subtype stratification tool for fresh‐frozen and paraffin‐embedded colorectal cancer samples

Molecular Oncology, EarlyView.
Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang, Simone van de Weerd, Veerle Lammers, Sander van Hooff, Inge van den Berg, Saskia van den Bergh, Miriam Koopman, Jan N. IJzermans, Jeanine M. L. Roodhart, Jan Koster, Jan Paul Medema   +10 more
wiley   +1 more source

`Standard' Cosmological model & beyond with CMB

, 2011
Observational Cosmology has indeed made very rapid progress in the past decade. The ability to quantify the universe has largely improved due to observational constraints coming from structure formation Measurements of CMB anisotropy and, more recently ...
Bennett C L, Bennett C L, Bond J R, Bond J R, Brown M L, Das S, Eisenstein D J, Eriksen H K, Hajian A, Hajian A, Hamann J, Hannestad S, Hinshaw G, Jain R K, Kogo N, Kogut A, Komatsu E, Larson D, Larson D L, MacTavish C J, Maity D, Matsumiya M, Mukherjee P, Mukherjee P, Page L, Reichardt C L, Rybicki G B, Saha R, Samal P, Shafieloo A Souradeep T, Souradeep T Bond J R Knox L Efstathiou G Turner M S Roszkowski L, Spergel D, Sunyaev R A, Tarun Souradeep   +33 more
core   +1 more source

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

Molecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran, Clarence Yapp, Gregory J. Baker, Johanna Beyer, Young Hwan Chang, Allison L. Creason, Robert Krueger, Jeremy Muhlich, Nathan Heath Patterson, Kevin Sidak, Damir Sudar, Adam J. Taylor, Luke Ternes, Jakob Troidl, Xie Yubin, Artem Sokolov, Darren R. Tyson   +16 more
wiley   +1 more source

Saxion cosmology for thermalized gravitino dark matter

Journal of High Energy Physics, 2017
In all supersymmetric theories, gravitinos, with mass suppressed by the Planck scale, are an obvious candidate for dark matter; but if gravitinos ever reached thermal equilibrium, such dark matter is apparently either too abundant or too hot, and is ...
Raymond T. Co, Francesco D’Eramo, Lawrence J. Hall, Keisuke Harigaya   +3 more
doaj   +1 more source