Results 51 to 60 of about 78,901 (140)

Does Administration Timing of Ondansetron, a 5-HT3 Receptor Antagonist, Affect Inhibition of the Bezold-Jarisch Reflex in OB C-section Patients Receiving Spinal Anesthesia [PDF]

, 2021
Ondansetron (a 5HT-3 receptor antagonist) has been shown in multiple randomized controlled trials (RCT’s) and meta-analysis to inhibit activation of Bezold-Jarisch Reflex (BJR) in response to spinal anesthesia for elective cesarean section patients ...
Zaharie, Spenser, Rowley, Matthew
core  

Cardiopulmonary arrest following extradural analgesia and suspected secondary sympathetic blockade in a critically ill dog

Veterinary Record Case Reports, Volume 14, Issue 2, May 2026.
Abstract An 8‐year‐old, male, entire Cocker Spaniel presented to the Queen Mother Hospital for Animals for treatment of an iatrogenic septic uroabdomen secondary to traumatic urinary catheterisation. After initial stabilisation, it underwent diagnostic imaging and definitive surgical correction comprising a cystotomy and bladder reconstruction.
Joe Simon, Manuel Enrique Herrera‐Linares, Hannah Louise Matson, Cristina Bianchi   +3 more
wiley   +1 more source

Hypohydration Increases Heart Rate Despite Preserved Hemodynamic Compensation During Blood Flow Restricted Exercise

Scandinavian Journal of Medicine &Science in Sports, Volume 36, Issue 5, May 2026.
ABSTRACT During blood flow restriction (BFR) exercise, blood becomes sequestered in the active limbs due to impeded venous return, contributing to central hypovolemia. Dehydration also reduces blood volume and can exacerbate the ability of the cardiovascular (CV) system to defend against CV stressors, such as exercise and orthostatic stress.
Christopher Pignanelli, Gavin C. Lydiate, Monica M. Grigore, Jenna C. McCrone, Katrin Turetskiy, Regan E. J. Parris, Ella M. Bisset‐Cavallin, Alexa A. Robertson, Alexander S. D. Gamble, Philip J. Millar, Michael M. Tymko, Jamie F. Burr   +11 more
wiley   +1 more source

The bradycardic and hypotensive responses to serotonin are reduced by activation of GABA A receptors in the nucleus tractus solitarius of awake rats [PDF]

Brazilian Journal of Medical and Biological Research, 2005
We investigated the effects of bilateral injections of the GABA receptor agonists muscimol (GABA A) and baclofen (GABA B) into the nucleus tractus solitarius (NTS) on the bradycardia and hypotension induced by iv serotonin injections (5-HT, 2 µg/rat) in ...
J.C. Callera, E. Colombari, L.A. De Luca Jr., J.V. Menani   +3 more
doaj   +1 more source

Stimulation of 5-HT3 receptors in the NTS inhibits the cardiac Bezold-Jarisch reflex response

, 1996
Intra-atrial administration of phenylbiguanide has been shown to trigger, through the stimulation of vagal afferent C-fibers, reflex bradycardia, hypotension, and sympathoinhibition classically known as the Bezold-Jarisch (B-J) reflex (O. Krayer. Naunyn-
Machado, Benedito H., Laguzzi, Raul, Nosjean, A., J. C. Callera, A. Nosjean, M. Hamon, Hamon, M., Callera, João Carlos, Hamon, Michel, C. Sevoz, Machado, B., B. Machado, Sevoz, C., Sévoz, Caroline, Laguzzi, R., R. Laguzzi, Callera, J., Nosjean, Anne   +17 more
core   +1 more source

Congenital Anomalous Origin of Coronary Artery Disease in Children With Syncope: A Case Series

Frontiers in Pediatrics, 2022
ObjectiveThis study is aimed to analyze the characteristics of congenital anomalous origin of coronary artery in pediatric patients with syncope.MethodsA total of eight patients were retrospectively analyzed from August 2018 to August 2020 who were ...
Yumeng Gao, Qingyou Zhang, Yan Sun, Junbao Du   +3 more
doaj   +1 more source

Effects of Intravenous Ondansetron and Granisetron on Haemodynamic Changes during Spinal Anaesthesia in Non-obstetric Population: A Randomised Double-blind Study [PDF]

Journal of Clinical and Diagnostic Research, 2019
Introduction: Two commonly used antiemetics in the perioperative period may attenuate the spinal anaesthesia induced hypotension by attenuating the Bezold-Jarisch Reflex (BJR).
Srihari Bommala, Madhusudan Mukkara, Aloka Samantaray, Hemalatha Pasupuleti, Dyva Manogna Reddycogu, Santhi Swetha Pudotha, Shravani Pabba, Sathish   +7 more
doaj   +1 more source

Neuroinflammation in the NTS is associated with changes in cardiovascular reflexes during systemic inflammation

Journal of Neuroinflammation, 2019
Background Lipopolysaccharide (LPS)-induced systemic inflammation (SI) is associated with neuroinflammation in the brain, hypotension, tachycardia, and multiple organs dysfunctions.
Mateus R. Amorim, Júnia L. de Deus, Rafael A. Cazuza, Clarissa M. D. Mota, Luiz E. V. da Silva, Gabriela S. Borges, Marcelo E. Batalhão, Evelin C. Cárnio, Luiz G. S. Branco   +8 more
doaj   +1 more source

The physiology, anatomy and stimulation of the vagus nerve in epilepsy

The Journal of Physiology, Volume 603, Issue 8, Page 2201-2217, 15 April 2025.
Abstract figure legend The vagus nerve is both the longest cranial nerve and the largest, providing parasympathetic control of multiple organ systems within the thorax and abdomen, including the cardiovascular, respiratory and gastrointestinal systems (Ottaviani & Macefield, 2022).
Mikaela Patros, Shobi Sivathamboo, Hugh D. Simpson, Terence J. O'Brien, Vaughan G. Macefield   +4 more
wiley   +1 more source

Crystalloid Co-loading versus Ondansetron Effect on Hemodynamic Stability of Cesarean Section Patients Anesthetized by Subarachnoid Block in Karbala, Iraq

Baghdad Journal of Biochemistry and Applied Biological Sciences
Background: Subarachnoid block-induced hypotension and bradycardia remain a frequent and clinically significant complications during cesarean section. Strategies such as fluid co-loading and ondansetron have been employed to mitigate these effects, but ...
Ali Abdulameer Kareem Kareem, Haidar Nassir Mohammed   +1 more
doaj   +1 more source