Results 1 to 10 of about 4,582 (179)

Baroreflex and chemoreflex interaction in high-altitude exposure: possible role on exercise performance

Frontiers in Physiology
The hypoxic chemoreflex and the arterial baroreflex are implicated in the ventilatory response to exercise. It is well known that long-term exercise training increases parasympathetic and decreases sympathetic tone, both processes influenced by the ...
Rodrigo Iturriaga, Gregoire Millet, Cristian Andrés Núñez Espinosa   +2 more
exaly   +4 more sources

Time-dependent alteration in the chemoreflex post-acute lung injury [PDF]

Frontiers in Physiology, 2022
Acute lung injury (ALI) induces inflammation that disrupts the normal alveolar-capillary endothelial barrier which impairs gas exchange to induce hypoxemia that reflexively increases respiration.
Kajal Kamra, Kajal Kamra, Nikolay Karpuk, Ryan Adam, Irving H. Zucker, Harold D. Schultz, Han-Jun Wang, Han-Jun Wang   +7 more
doaj   +2 more sources

Influence of low‐dose dopamine on exercise in fibrosing interstitial lung disease [PDF]

Experimental Physiology
Fibrotic interstitial lung disease (FILD) is associated with dyspnoea and exercise intolerance. In other cardiorespiratory conditions, heightened carotid body (CB) chemoreflex sensitivity is associated with reduced exercise capacity.
Charlotte Chen, Jui‐Lin Fan, Michael Plunkett, Thalia Babbage, John Kolbe, Julian F. R. Paton, James P. Fisher   +6 more
doaj   +2 more sources

Orexin facilitates the peripheral chemoreflex in the active phase via corticotropin-releasing hormone neurons that project to the nucleus of the solitary tract [PDF]

Function
Projections from the paraventricular nucleus (PVN) of the hypothalamus to the nucleus of the solitary tract (nTS) facilitate the peripheral chemoreflex.
Ruwaida Ben Musa, Fateme Khodadadi-Mericle, David D. Kline, Eileen M. Hasser, Kevin J. Cummings   +4 more
doaj   +2 more sources

The Role of Pharmacological Treatment in the Chemoreflex Modulation

Frontiers in Physiology, 2022
From a physiological point of view, peripheral chemoreceptors (PCh) are the main sensors of hypoxia in mammals and are responsible for adaptation to hypoxic conditions.
Piotr Niewinski, Stanislaw Tubek, Piotr Ponikowski   +2 more
exaly   +3 more sources

Potential Role of the Retrotrapezoid Nucleus in Mediating Cardio-Respiratory Dysfunction in Heart Failure With Preserved Ejection Fraction

Frontiers in Physiology, 2022
A strong association between chemoreflex hypersensitivity, disordered breathing, and elevated sympathetic activity has been shown in experimental and human heart failure (HF).
Camilo Toledo, Camilo Toledo, Domiziana Ortolani, Fernando C. Ortiz, Noah J. Marcus, Rodrigo Del Rio, Rodrigo Del Rio, Rodrigo Del Rio   +7 more
doaj   +1 more source

The superior cervical ganglion is involved in chronic chemoreflex sensitization during recovery from acute lung injury

Frontiers in Physiology, 2023
Introduction: Acute lung injury (ALI) initiates an inflammatory cascade that impairs gas exchange, induces hypoxemia, and causes an increase in respiratory rate (fR). This stimulates the carotid body (CB) chemoreflex, a fundamental protective reflex that
Kajal Kamra, Kajal Kamra, Nikolay Karpuk, Irving H. Zucker, Harold D. Schultz, Han-Jun Wang, Han-Jun Wang   +6 more
doaj   +1 more source

Role of the Kölliker-Fuse nucleus in cardiovascular responses to hypoxia and baroreceptor activation in anesthetized rats [PDF]

BioImpacts, 2020
Introduction: Parabrachial Kölliker-Fuse (KF) complex, located in dorsolateral part of the pons, is involved in the respiratory control, however, its role in the baroreflex and chemoreflex responses has not been established yet.
Nafiseh Mirzaei-Damabi, Bahar Rostami, Masoumeh Hatam   +2 more
doaj   +1 more source

Measuring Peripheral Chemoreflex Hypersensitivity in Heart Failure

Frontiers in Physiology, 2020
Heart failure with reduced ejection fraction (HFrEF) induces chronic sympathetic activation. This disturbance is a consequence of both compensatory reflex disinhibition in response to lower cardiac output and patient-specific activation of one or more ...
Daniel A. Keir, Daniel A. Keir, James Duffin, James Duffin, James Duffin, John S. Floras   +5 more
doaj   +1 more source

Carotid chemoreflex and muscle metaboreflex interact to the regulation of ventilation in patients with heart failure with reduced ejection fraction

Physiological Reports, 2020
Synergism among reflexes probably contributes to exercise hyperventilation in patients with heart failure with reduced ejection fraction (HFrEF). Thus, we investigated whether the carotid chemoreflex and the muscle metaboreflex interact to the regulation
Alessandro C. Machado, Lauro C. Vianna, Erika A. C. Gomes, Jose A. C. Teixeira, Mario L. Ribeiro, Humberto Villacorta, Antonio C. L. Nobrega, Bruno M. Silva   +7 more
doaj   +1 more source