Construction of BHV-1 UL41 Defective Virus Using the CRISPR/Cas9 System and Analysis of Viral Replication Properties [PDF]
Frontiers in Cellular and Infection Microbiology, 2022 Bovine herpesvirus type 1 (BHV-1) is a neurotropic herpesvirus that causes infectious rhinotracheitis and vulvovaginitis in cattle. The virion host shutoff protein encoded by the BHV-1 UL41 gene is highly conserved in the Alphaherpesvirinae subfamily ...
Haiyue Dai +6 more
doaj +2 more sources
Exploration of semen quality analyzed by casa-mot systems of brahman bulls infected with BLV and BHV-1 [PDF]
Scientific Reports, 2023 Enzootic bovine leukosis virus (BLV) and bovine herpesvirus 1 (BHV-1) are very important infectious agents for the livestock industry worldwide. The present study aimed to explore the association between natural exposure to BLV and BHV-1 with sperm ...
Derling Pichardo-Matamoros +7 more
doaj +2 more sources
Degenerate PCR method for identification of an antiapoptotic gene in BHV-1 [PDF]
Journal of Cellular Biochemistry, 2006 To investigate on the hypothetical presence of an antiapoptotic gene, we utilized the CODEHOP (COnsensus-DEgenerate Hybrid Oligonucleotide Primers) strategy amplifying unknown sequences from a background of genomic (bovine herpesvirus type-1) BHV-1 DNA ...
Ciriolo, MR +9 more
core +8 more sources
Atividade neutralizante anti-herpesvírus bovino tipos 1 (BHV-1) e 5 (BHV-5) no soro de bovinos imunizados com vacinas contra o BHV-1 [PDF]
Ciência Rural, 2002 Bezerros foram imunizados com duas vacinas contra o herpesvírus bovino tipo 1 (BHV-1; vacina A, n=28; B, n=28) ou com uma vacina contendo antígenos do BHV-1 e BHV-5 (n=32) e a atividade neutralizante sérica antiBHV-1 e BHV-5 foi testada após três doses ...
Fernanda Silveira Flores Vogel +3 more
doaj +4 more sources
Application of Bovine Nasal Epithelial Cells as an In Vitro Model for Studying Viral Infection in the Upper Respiratory Tract [PDF]
VirusesBovine respiratory disease complex (BRDC) is a multifactorial and globally prevalent condition involving a combination of viral and bacterial pathogens, as well as environmental stressors.
Malte Pitters +4 more
doaj +2 more sources
Pathogenic mechanisms implicated in the intravascular coagulation in the lungs of BVDV-infected calves challenged with BHV-1. [PDF]
Vet Res, 2013 Resistance to respiratory disease in cattle requires host defense mechanisms that protect against pathogens which have evolved sophisticated strategies to evade them, including an altered function of pulmonary macrophages (MΦs) or the induction of ...
Risalde MA +7 more
europepmc +3 more sources
BHV-1 induced oxidative stress contributes to mitochondrial dysfunction in MDBK cells. [PDF]
Vet Res, 2016 The levels of cellular reactive oxygen species (ROS) and ATP as well as the mitochondrial membrane potential (MMP) in response to bovine herpesvirus 1 (BHV-1) infection of MDBK cells were measured, respectively. BHV-1 infection increased ROS production which depended on viral entry, and de novo protein expression and/or DNA replication.
Zhu L +5 more
europepmc +4 more sources
2,3,7,8-Tetrachlorodibenzo-p-dioxin promotes BHV-1 infection in mammalian cells by interfering with iron homeostasis regulation. [PDF]
PLoS ONE, 2013 Mammalian cells require iron to satisfy metabolic needs or to accomplish specialized functions, and DNA viruses, like bovine herpesvirus 1 (BHV-1), require an iron-replete host to efficiently replicate, so that iron bioavailability is an important ...
Filomena Fiorito +7 more
doaj +2 more sources
Enhanced efficacy with azacytidine and oncolytic BHV-1 in a tolerized cotton rat model of breast adenocarcinoma [PDF]
Molecular Therapy: Oncolytics, 2015 Oncolytic viruses selectively replicate in cancer cells by exploiting biochemical differences between normal and tumor cells. Treatment with epigenetic modifiers such as 5-Azacytidine, a DNA methyltransferase inhibitor, increases the replication and ...
Breanne P Cuddington +3 more
doaj +2 more sources
Develop an indirect ELISA utilizing gD protein to detect antibodies against bovine herpesvirus type 1 [PDF]
Frontiers in Cellular and Infection MicrobiologyBovine herpesvirus type 1 (BHV-1) is a highly contagious DNA virus that causes a variety of diseases affecting the reproductive and respiratory tracts.
Qiang Liu +11 more
doaj +2 more sources