Construction of BHV-1 UL41 Defective Virus Using the CRISPR/Cas9 System and Analysis of Viral Replication Properties [PDF]
Frontiers in Cellular and Infection Microbiology, 2022 Bovine herpesvirus type 1 (BHV-1) is a neurotropic herpesvirus that causes infectious rhinotracheitis and vulvovaginitis in cattle. The virion host shutoff protein encoded by the BHV-1 UL41 gene is highly conserved in the Alphaherpesvirinae subfamily ...
Haiyue Dai, Yongli Guo, Junwei Wang
exaly +4 more sources
Exploration of semen quality analyzed by casa-mot systems of brahman bulls infected with BLV and BHV-1 [PDF]
Scientific Reports, 2023 Enzootic bovine leukosis virus (BLV) and bovine herpesvirus 1 (BHV-1) are very important infectious agents for the livestock industry worldwide. The present study aimed to explore the association between natural exposure to BLV and BHV-1 with sperm ...
Derling Pichardo-Matamoros +7 more
doaj +2 more sources
Application of Bovine Nasal Epithelial Cells as an In Vitro Model for Studying Viral Infection in the Upper Respiratory Tract [PDF]
VirusesBovine respiratory disease complex (BRDC) is a multifactorial and globally prevalent condition involving a combination of viral and bacterial pathogens, as well as environmental stressors.
Malte Pitters +4 more
doaj +2 more sources
2,3,7,8-Tetrachlorodibenzo-p-dioxin promotes BHV-1 infection in mammalian cells by interfering with iron homeostasis regulation. [PDF]
PLoS ONE, 2013 Mammalian cells require iron to satisfy metabolic needs or to accomplish specialized functions, and DNA viruses, like bovine herpesvirus 1 (BHV-1), require an iron-replete host to efficiently replicate, so that iron bioavailability is an important ...
Filomena Fiorito +7 more
doaj +2 more sources
Enhanced efficacy with azacytidine and oncolytic BHV-1 in a tolerized cotton rat model of breast adenocarcinoma [PDF]
Molecular Therapy: Oncolytics, 2015 Oncolytic viruses selectively replicate in cancer cells by exploiting biochemical differences between normal and tumor cells. Treatment with epigenetic modifiers such as 5-Azacytidine, a DNA methyltransferase inhibitor, increases the replication and ...
Breanne P Cuddington +3 more
doaj +2 more sources
Develop an indirect ELISA utilizing gD protein to detect antibodies against bovine herpesvirus type 1 [PDF]
Frontiers in Cellular and Infection MicrobiologyBovine herpesvirus type 1 (BHV-1) is a highly contagious DNA virus that causes a variety of diseases affecting the reproductive and respiratory tracts.
Qiang Liu +11 more
doaj +2 more sources
DIFERENCIAÇÃO ENTRE OS VÍRUS DA RINOTRAQUEÍTE INFECCIOSA BOVINA (BHV-1) E HERPESVÍRUS DA ENCEFALITE BOVINA (BHV-5) COM ANTICORPOS MONOCLONAIS [PDF]
Pesquisa Veterinária Brasileira, 1997 Amostras de herpesvírus bovinos (BHV) tipo 1 (Virus da Rinotraqueíte Infecciosa Bovina/Vulvovaginite Pustular Infecciosa; BHV-1) e tipo 5 (Herpesvírus da Encefalite Bovina; BHV-5) tiveram seu perfil de reatividade analisado em testes de imunoperoxidase ...
Paulo Michel Roehe +4 more
doaj +1 more source
Frontiers in Microbiology, 2022 Bovine herpesvirus type 1 (BHV-1) causes bovine respiratory disease that poses a significant threat to the cattle industry. The prevalence of BHV-1 has recently increased in China.
Weiqiang Guo +4 more
doaj +1 more source
Replicação e excreção viral durante a infecção aguda e após a reativação da latência induzida por dexametasona em bezerros inoculados com os herpesvírus bovinos tipo 1 (BHV-1) e 5 (BHV-5) [PDF]
Ciência Rural, 2004 Nesse estudo, comparou-se a eficiência de estabelecimento e reativação da infecção latente pelos herpesvírus bovinos tipos 1 e 5 (BHV-1 e 5) em bezerros. Bezerros inoculados pela via intranasal com uma amostra de BHV-1 (SV-265, n=6) ou BHV-5 (SV-507, n=6)
Fernanda Silveira Flores Vogel +7 more
doaj +1 more source
Bovine herpesvirus type 1 (BHV-1) UL49.5 luminal domain residues 30 to 32 are critical for MHC-I down-regulation in virus-infected cells. [PDF]
PLoS ONE, 2011 Bovine herpesvirus type 1 (BHV-1) U(L)49.5 inhibits transporter associated with antigen processing (TAP) and down-regulates cell-surface expression of major histocompatibility complex (MHC) class I molecules to promote immune evasion. We have constructed
Huiyong Wei +2 more
doaj +1 more source