Results 51 to 60 of about 1,100,375 (298)

Regression Models and Fuzzy Logic Prediction of TBM Penetration Rate

open access: yesOpen Engineering, 2017
This paper presents statistical analyses of rock engineering properties and the measured penetration rate of tunnel boring machine (TBM) based on the data of an actual project.
Minh Vu Trieu   +3 more
doaj   +1 more source

covsim: An R Package for Simulating Non-Normal Data for Structural Equation Models Using Copulas

open access: yesJournal of Statistical Software, 2022
In factor analysis and structural equation modeling non-normal data simulation is traditionally performed by specifying univariate skewness and kurtosis together with the target covariance matrix.
Steffen Grønneberg   +2 more
doaj   +1 more source

Bis(adeninium) bis(hydrogensulfate) sulfate [PDF]

open access: yesActa Crystallographica Section E Structure Reports Online, 2012
تم تصنيع مركب العنوان، 2C5H7N5 (2+)·2HSO4(-) · SO4 (2 -)، من الأدينين وحمض الكبريتيك. تحتوي الوحدة غير المتماثلة على اثنين من كاتيونات الأدينينيوم ثنائية البروتونات، واثنين من الأنيونات ثنائية الكبريتات وأنيونات كبريتات واحدة. يتم تثبيت البنية البلورية من خلال الروابط الهيدروجينية الكلاسيكية N - H? O و O - H? O، والروابط الهيدروجينية الضعيفة C - H? O و
Fatiha Guenifa   +4 more
openaire   +3 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

DEVELOPMENT OF ERP AND OTHER LARGE BUSINESS SYSTEMS IN THE CONTEXT OF NEW TRENDS AND TECHNOLOGIES

open access: yesVallis Aurea, 2017
This paper presents an overview of terms, concepts, trends and technologies that are relevant to today's business. It describes the basics of data and information integration and flow in a company through a central ERP system with concepts of CRM and SCM.
Sabrina Suman, Ivan Pogarcic
doaj   +1 more source

Balansert lederskap

open access: yesMagma, 2020
Denne artikkelen diskuterer hvordan man kan kombinere vertikalt og horisontalt lederskap effektivt i prosjekter, altså hvordan lederskapet i prosjektet kan skifte mellom teammedlemmer og den formelt utpekte prosjektlederen avhengig av situasjonens krav.
Anne Live Vaagaasar, Ralf Müller
doaj   +1 more source

Bi-LSTM-A model architecture. [PDF]

open access: yes, 2022
Bi-LSTM-A model architecture.
Alan Godfrey (3145152)   +6 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Synthesis and Antibacterial Evaluation of Bis‐thiazolium, Bis‐imidazolium, and Bis‐triazolium Derivatives [PDF]

open access: yesChemMedChem, 2019
AbstractGiven the worldwide spread of bacterial drug resistance, there is an urgent need to develop new compounds that exhibit potent antibacterial activity and that are unimpaired by this phenomenon. Quaternary ammonium compounds have been used for many years as disinfectants, but recent advances have shown that polycationic derivatives exhibit much ...
Thomas, Benoît   +4 more
openaire   +2 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

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