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Empowering the deaf. Let the deaf be deaf [PDF]

Journal of Epidemiology and Community Health, 2000
Deafness is often regarded as just a one and only phenomenon. Accordingly, deaf people are pictured as a unified body of people who share a single problem. From a medical point of view, we find it usual to work with a classification of deafness in which pathologies attributable to an inner ear disorder are segregated from pathologies attributable to an
Muñoz Baell, Irma María, Ruiz Cantero, María Teresa   +1 more
openaire   +3 more sources

Parenting stress and needs for social support in mothers and fathers of deaf or hard of hearing children

Frontiers in Psychology, 2023
IntroductionHearing parents of deaf or hard of hearing (DHH) children may experience parenting stress and social support could be a buffer to this stress. Differences in levels of these two indicators may exist between mothers and fathers.
Amélie Marie, Laëtitia Clabaut, Marjolaine Corbeil, Clémence Vanlerberghe, Catherine Vincent-Delorme, Barbara Le Driant   +5 more
doaj   +1 more source

ASTX660, an antagonist of cIAP1/2 and XIAP, increases antigen processing machinery and can enhance radiation-induced immunogenic cell death in preclinical models of head and neck cancer

OncoImmunology, 2020
Inhibitor of apoptosis protein (IAP) antagonists have shown activity in preclinical models of head and neck squamous cell carcinoma (HNSCC), and work across several cancer types has demonstrated diverse immune stimulatory effects including enhancement of
Wenda Ye, Sreenivasulu Gunti, Clint T. Allen, Youji Hong, Paul E. Clavijo, Carter Van Waes, Nicole C. Schmitt   +6 more
doaj   +1 more source

Comprehensive multiomic characterization of human papillomavirus-driven recurrent respiratory papillomatosis reveals distinct molecular subtypes

Communications Biology, 2021
Cem Sievers et al. performed genomic and transcriptomic analysis in human recurrent respiratory papillomatosis (RRP). They found that RRP harbors few genomic alterations, but that distinct transcriptional subtypes correlate with HPV gene expression and ...
Cem Sievers, Yvette Robbins, Ke Bai, Xinping Yang, Paul E. Clavijo, Jay Friedman, Andrew Sinkoe, Scott M. Norberg, Christian Hinrichs, Carter Van Waes, Clint T. Allen   +10 more
doaj   +1 more source

The Effect of Lifetime Noise Exposure and Aging on Speech-Perception-in-Noise Ability and Self-Reported Hearing Symptoms: An Online Study

Frontiers in Aging Neuroscience, 2022
Animal research shows that aging and excessive noise exposure damage cochlear outer hair cells, inner hair cells, and the synapses connecting inner hair cells with the auditory nerve.
Adnan M. Shehabi, Adnan M. Shehabi, Garreth Prendergast, Hannah Guest, Christopher J. Plack, Christopher J. Plack   +5 more
doaj   +1 more source

Transient evoked otoacoustic emissions testing for screening of sensorineural deafness in puppies [PDF]

, 2011
<p><b>Background:</b> Transient evoked otoacoustic emissions (TEOAE) are widely used for human neonatal deafness screening, but have not been reported for clinical use in dogs.</p> <p><b>Hypothesis/Objectives:< ...
Ahlstrom, Branis, De Capua, Doyle, Famula, Hall, Igarashi, Kemp, Korres, Lonsbury-Martin, Lonsbury-Martin, Lurie, Maxon, Platt, Rhodes, Schemera, Sims, Sockalingam, Strain, Strain, Strain, Strain, Ter Haar, Wilkes, Wilson, Wood   +25 more
core   +1 more source

Selective binding and transport of protocadherin 15 isoforms by stereocilia unconventional myosins in a heterologous expression system

Scientific Reports, 2022
During hair cell development, the mechanoelectrical transduction (MET) apparatus is assembled at the stereocilia tips, where it coexists with the stereocilia actin regulatory machinery.
Angela Ballesteros, Manoj Yadav, Runjia Cui, Kiyoto Kurima, Bechara Kachar   +4 more
doaj   +1 more source

Molecular diagnostics for congenital hearing loss including 15 deafness genes using a next generation sequencing platform [PDF]

, 2012
Background: Hereditary hearing loss (HL) can originate from mutations in one of many genes involved in the complex process of hearing. Identification of the genetic defects in patients is currently labor intensive and expensive.
Bekaert, Sofie, Coucke, Paul, De Keulenaer, Sarah, De Schrijver, Joachim, Deforce, Dieter, Flamez, Daisy, Hellemans, Jan, Lefever, Steve, Pattyn, Filip, Renard, Jean-Pierre, Scharlaken, Bieke, Tabatabaiefar, Mohammad Amin, Van Camp, Guy, Van Criekinge, Wim, Van de Voorde, Hendrik, Van Nieuwerburgh, Filip, Vandesompele, Jo   +16 more
core   +2 more sources

A destressing "deafness" in French? [PDF]

, 1997
French is a language in which accent is mandatory on the last syllable of every content word. In contrast, Spanish uses accent to distinguish different lexical items (e.g., b'ebe vs beb'e).
Dupoux, E., Mehler, J., Pallier, C., Sebastian, N.   +3 more
core   +4 more sources

WEE1 kinase inhibition reverses G2/M cell cycle checkpoint activation to sensitize cancer cells to immunotherapy

OncoImmunology, 2018
Intrinsic resistance to cytotoxic T-lymphocyte (CTL) killing limits responses to immune activating anti-cancer therapies. Here, we established that activation of the G2/M cell cycle checkpoint results in tumor cell cycle pause and protection from ...
Lillian Sun, Ellen Moore, Rose Berman, Paul E. Clavijo, Anthony Saleh, Zhong Chen, Carter Van Waes, John Davies, Jay Friedman, Clint T. Allen   +9 more
doaj   +1 more source