Relative changes in the cochlear summating potentials to paired-clicks predict speech-in-noise perception and subjective hearing acuity [PDF]
Objective assays of human cochlear synaptopathy (CS) have been challenging to develop. It is suspected that relative summating potential (SP) changes are different in listeners with CS.
Jesyin Lai, Gavin M. Bidelman
doaj +2 more sources
Detecting Noise-Induced Cochlear Synaptopathy by Auditory Brainstem Response in Tinnitus Patients With Normal Hearing Thresholds: A Meta-Analysis [PDF]
Noise-induced cochlear synaptopathy (CS) is defined as a permanent loss of synapses in the auditory nerve pathway following noise exposure. Several studies using auditory brainstem response (ABR) have indicated the presence of CS and increased central ...
Feifan Chen +4 more
doaj +2 more sources
Electrocochleographic Changes Predict an Early Sign of Cochlear Degeneration. [PDF]
ABSTRACT Objectives The purpose of this study is to identify the earliest appearing auditory electrophysiological indicators that change with age progression in young adults with normal hearing, and to analyze the frequency distribution patterns of these markers in the cochlear.
Qian MF +6 more
europepmc +2 more sources
Acute Recreational Noise-Induced Cochlear Synaptic Dysfunction in Humans With Normal Hearing: A Prospective Cohort Study [PDF]
ObjectivesThe objective of the study was to identify the acute high-intensity recreational noise-induced effects on auditory function, especially the cochlear synaptopathy-related audiological metrics, in humans with normal hearing.MethodsThis ...
Qixuan Wang +20 more
doaj +2 more sources
No effect of occupational noise exposure on auditory brainstem response and speech perception in noise [PDF]
The primary aim of this study was to investigate whether auditory brainstem response (ABR) and speech perception in noise (SPiN) were associated with occupational noise exposure in normal hearing young factory workers.
Alexis Pinsonnault-Skvarenina +9 more
doaj +2 more sources
Altered Paired-Click Auditory Brainstem Responses in Normal-Hearing Young Adults With Frequent Loud Sound Exposure [PDF]
This study investigated differences in auditory brainstem responses (ABRs) using the paired-click paradigm between young adults frequently exposed to loud sounds and those not.
Haruna Fujihira +5 more
doaj +2 more sources
Large-scale music events can cause subclinical hearing damage [PDF]
The WHO warns that over 1.1 billion young people are at risk of hearing loss due to unsafe listening practices, particularly in recreational settings. While traditional studies have focused on changes in hearing sensitivity, typically assessed through ...
Nele De Poortere +6 more
doaj +2 more sources
Cochlear Synaptopathy Evaluation With Electrocochleography in Patients With Hearing Difficulty in Noise Despite Normal Hearing Levels. [PDF]
ABSTRACT Objective This study examined patients with normal hearing thresholds who had trouble understanding speech in noise. We used electrocochleography (ECochG) to detect and compare SP/AP amplitude area ratios, a potential indicator of cochlear synaptopathy, and investigate speech perception disorder in noise.
Yaşar M, Öner F, Atalay F, Anbar SS.
europepmc +2 more sources
The Relative and Combined Effects of Noise Exposure and Aging on Auditory Peripheral Neural Deafferentation: A Narrative Review [PDF]
Animal studies have shown that noise exposure and aging cause a reduction in the number of synapses between low and medium spontaneous rate auditory nerve fibers and inner hair cells before outer hair cell deterioration.
Adnan M. Shehabi +4 more
doaj +2 more sources
Dose-Dependent Pattern of Cochlear Synaptic Degeneration in C57BL/6J Mice Induced by Repeated Noise Exposure. [PDF]
It is widely accepted that even a single acute noise exposure at moderate intensity that induces temporary threshold shift (TTS) can result in permanent loss of ribbon synapses between inner hair cells and afferents. However, effects of repeated or chronic noise exposures on the cochlear synapses especially medial olivocochlear (MOC) efferent synapses ...
Qian M +7 more
europepmc +2 more sources

