Results 81 to 90 of about 1,685,795 (292)

Where to Initiate Basal Insulin Therapy: Inpatient or Outpatient Department? Real-World Observation in China

open access: yesDiabetes, Metabolic Syndrome and Obesity, 2022
Minyuan Chen,1,* Puhong Zhang,1,2,* Yang Zhao,1,3 Nadila Duolikun,1 Linong Ji4 1The George Institute for Global Health, China, Beijing, 100600, People’s Republic of China; 2The George Institute for Global Health, Faculty of Medicine, University ...
Chen M   +4 more
doaj  

Intrapreneurial Behaviour at BI Norwegian Business School : A Qualitative Study on the Success of BI2020 Pilot Program [PDF]

open access: yes, 2019
Masteroppgave(MSc) in Master of Science in Leadership and Organizational Psychology - Handelshøyskolen BI, 2019The purpose of this research study was to investigate and shed light on intrapreneurial behaviour at BI Norwegian Business School. This thesis
Holter, Lena Houge   +1 more
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Bi-LSTM-A model architecture.

open access: yes, 2022
Bi-LSTM-A model architecture.
Alan Godfrey (3145152)   +6 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Breeding population of Black Stork, Ciconia nigra, in Italy between 1994 and 2016

open access: yesRivista Italiana di Ornitologia - Research in Ornithology, 2018
The Black Stork Ciconia nigra, following an expansion on European scale, started breeding in Italy in 1994 with one pair in the Piedmont Region and one in the Calabria Region.
Maurizio Fraissinet   +10 more
doaj   +1 more source

Utmattelse - En sikkerhetsrisiko i militær ubemannet luftfart? [PDF]

open access: yes, 2021
Executive Master of Management ved Handelshøyskolen BI ...
Skjefstad, Kristian Gundersen   +2 more
core  

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

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