Results 241 to 250 of about 1,100,375 (298)

TME/NIR Dual‐Responsive Zinc‐Based Targeted Nanoagonist for Multimodal Amplification of STING‐Mediated Cancer Immunotherapy

Advanced Science, EarlyView.
A multifunctional nanoagonist (cDZ@IP) enables nano‐metabolite–driven multimodal activation of the STING pathway and enhanced immune recognition, achieving potent antitumor immunity and suppressing tumor growth and metastasis. This strategy highlights the rational design of therapeutic metabolites and establishes a new paradigm bridging nanomedicine ...
Kepeng Hu, Jiawei Wang, Wei Zhang, Zhixuan Wu, Jing Chen, Yujing He, Xiyue Duan, Yaoting He, Xin Xin, Haoyi Xiang, Yijing Wang, Chengwei Wu, Yang Yi, Qing Meng, Yuqian Qiao, Kui Cheng, Xiaojun Long, Zhangfa Song   +17 more
wiley   +1 more source

Streptavidins Coordinate Biotin Sequestration and Self‐Resistance Within a Biotin‐Pathway Antibiotic Network

Advanced Science, EarlyView.
A conserved genomic region between two streptavidin genes in Streptomyces packages biosynthetic gene clusters for diverse biotin‐pathway antibiotics: acidomycin, stravidin, the new non‐proteinogenic amino acid ANDA, and the new BioA inhibitor α‐methyl‐KAPA.
Sumire Kurosawa, Jingjun Mo, Xiaotong Diao, Feng Xie, Tingting Wang, Haowen Zhao, Dalei Wu, Rolf Müller, Chengzhang Fu   +8 more
wiley   +1 more source

Synergistic antibacterial effect of photocatalytic coatings activated by visible light and photodynamic therapy for rapid peri-implantitis treatment. [PDF]

Bioact Mater
Nagay BE, Costa RC, Malheiros SS, Cordeiro JM, Dini C, Santos AB, Cantiga C, Rios BR, Li X, Ruixin Z, Rao X, Stolf CS, Casarin RCV, da Cruz NC, de Souza FHV, Cintra LTA, Gnanasekar S, Murugesan S, Xu L, Faverani LP, van den Beucken JJJP, Barão VAR.   +21 more
europepmc   +1 more source

Multimodal Imaging Reveals Rapid Catecholamine Uptake and Release by Neutrophils

Advanced Science, EarlyView.
We show that immune cells (neutrophils) synthesize, uptake, and store catecholamine neurotransmitters such as dopamine or adrenaline. They also release them in response to specific stimuli (serotonin), which we directly visualize using fluorescent nanosensors. We further demonstrate that catecholamines affect neutrophil functions (NETosis) and platelet
Jennifer Mohr, Anne Schmitz, Meshkat Dinarvand, Franziska Wulfert, Sangeetha Shankar, Bjoern F. Hill, Michael Wojak, Juliana Gretz, Marie Britz, Elsa Neubert, Magdalena Shumanska, Sofia Kaushik, Linda Kartaschew, Ivan Bogeski, James Daniel, Sebastian Jung, Johannes Eble, Guido Wabnitz, Luise Erpenbeck, Sebastian Kruss   +19 more
wiley   +1 more source

Breast Imaging Reporting and Data System v2025: Key Updates in US. [PDF]

J Korean Soc Radiol
Chang JM, Ha SM, Yoen H.
europepmc   +1 more source

Polymorphic Superparaelectric Engineering Boosting Energy Storage Capacity in BaTiO3‐Based Ceramics

Advanced Science, EarlyView.
Herein, Ca2+ incorporation promotes the coexistence of CaTiO3‐/BaTiO3‐derived paraferroelectric states, stabilizing cubic‐orthorhombic‐tetragonal polymorphic superparaelectric phases. This minimizes polarization energy barriers, facilitating full polarization saturation without compromising efficiency.
Pan Liu, Xiang Ren, Jin Qian, Haihua Huang, Peng Li, Peng Fu, Jigong Hao, Huarong Zeng, Wei Li, Zhenxiang Cheng   +9 more
wiley   +1 more source

Side-level versus patient-level evaluation in four-view mammography classification: a comprehensive benchmark on the CMMD dataset. [PDF]

Future Sci OA
Mabrok MA.
europepmc   +1 more source

Rescaling and Asymptotic Acceleration in Unconstrained Quadratic Optimisation. [PDF]

Mathematica (N Y)
Zverovich A, Hutchings M, Gauthier B.
europepmc   +1 more source

Breast Imaging Reporting and Data System v2025: Key Updates in Mammography. [PDF]

J Korean Soc Radiol
Kang BJ.
europepmc   +1 more source

Microscopic Insights into Impurity-Modulated Capture of Platinum-Group Metals by Bismuth in Copper Anode Slimes. [PDF]

Molecules
Liu D, Zeng H, Liu F, Cao J, Xiong H, Chen F, Zhang T, Wang J.   +7 more
europepmc   +1 more source