ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane +43 more
wiley +1 more source
Pengaruh Perubahan BI Rate Terhadap Market Return Dan Volatilitas Indeks LQ45
This study aimed to examine the effect of the announcement of the change in the BI rate to market return and volatility on the index LQ45 during the period March 2010 to February 2015 by using inflation and industrial production index as variable control.
Alan Fatih, Fitri Ismiyanti
doaj +1 more source
Understanding CP phase-dependent measurements at neutrino superbeams in terms of bi-rate graphs
We discuss the impact of the true value of the CP phase on the mass hierarchy, CP violation, and CP precision measurements at neutrino superbeams and related experiments.
Winter, Walter
core +2 more sources
Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz +9 more
wiley +1 more source
Penelitian ini bertujuan untuk menemukan bukti empiris mengenai Pengaruh Tingkat Inflasi, BI Rate, Kurs Dollar (USD/IDR) terhadap Indeks Harga Saham Gabungan (IHSG).
Kukuh Listriono, Elva Nuraina
doaj +1 more source
Dampak Inflasi, Bi Rate, Capital Adequacy Ratio (Car), Biaya Operasional Pendapatan Operasional (Bopo)terhadap Nonperforming Financing (NPF) Pada Bank Umumsyariah Di Indonesia [PDF]
One of the factors Which can be used to review indicates Banking Crisis Is non-performing financing (NPF), Therefore By analyzing the factors that determine the level of financing problems Anything important and substantial for Financial Stability and ...
RIKA, R. L. (RIKA)
core
10 Gbit/s bit interleaving CDR for low-power PON [PDF]
A novel, low power, downstream clock and data recovery (CDR)- decimator architecture is proposed for next generation, energy efficient 10 Gbit/s optical network units (ONUs).
Chow, Hungkei +7 more
core +2 more sources
A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Macro Economic Challenges and Third Party Funds of Islamic Commercial Banks in Indonesia
This article aims to determine the effect of inflation, the BI Rate, the exchange rate of the rupiah to the US dollar, and the amount of money supply for Third Party Funds (TPF) in Indonesians’ Islamic Banks during 2013-2016. This research method uses
Anik Anik, Iin Emy Prastiwi
doaj +1 more source

