Results 141 to 150 of about 55,568 (292)

A Systematic Review and Meta‐Analysis of Semaglutide Effects on Adipose Tissue and Emerging Effects on Brain and Cognition

Obesity Reviews, EarlyView.
ABSTRACT Background In 2023 and 2024, research into semaglutide (SEMA), an antiobesity and antidiabetic medication, indicated potential benefits beyond its approved uses, particularly in preventing Alzheimer's disease (AD). This highlights the link between obesity and AD development.
Amene Saghazadeh, Mahsa Dolatshahi, Soheil Mohammadi, Sara Hosseinzadeh Kassani, Mahshid Naghashzadeh, Joseph E. Ippolito, Claude B. Sirlin, Bettina Mittendorfer, Matthew R. Brier, Suzanne E. Schindler, John C. Morris, Danny Mou, Hani Charles Soudah, Tammie L. S. Benzinger, Cyrus A. Raji   +14 more
wiley   +1 more source

BAdd: Bias Mitigation Through Bias Addition

2025 IEEE/CVF International Conference on Computer Vision Workshops (ICCVW)
Computer vision datasets often exhibit biases in the form of spurious correlations between certain attributes and target variables. While recent efforts aim to mitigate such biases and foster bias-neutral representations, they fail in complex real-world scenarios. In particular, existing methods excel in controlled experiments on benchmarks with single-
Sarridis, Ioannis, Koutlis, Christos, Papadopoulos, Symeon, Diou, Christos   +3 more
openaire   +3 more sources

Effects of Glucagon‐Like Peptide‐1 Receptor Agonists (Mono and Combination Therapy) on Energy Expenditure: A Scoping Review

Obesity Reviews, EarlyView.
ABSTRACT Introduction Weight loss results in reduced energy expenditure (EE) due to body composition alterations (e.g., fat‐free mass and fat mass losses) and mass‐independent adaptations in EE (e.g., hormones). Glucagon‐like peptide‐1 receptor agonists (GLP‐1RA) are indicated for obesity management; however, their effects on EE remain unclear ...
Flavio T. Vieira, ZhiDi Deng, Manfred J. Muller, Giovanna G. L. Bergamasco, Sarah Cawsey, Melania Manco, Steven B. Heymsfield, Carla M. Prado, Andrea M. Haqq   +8 more
wiley   +1 more source

Analyzing the determinants influencing the customer satisfaction level of Bandaranaike International Airport services (BIA) : a quantitative approach [PDF]

This Master thesis research aims at investigating the determinants that affect passenger satisfaction in Bandaranaike International Airport Services (BIA) in Sri Lanka. Application of the SERVQUAL model as the leading analytic model.
Ranasinghe, Lakshika
core  

Mechanistic Insights into AAV Capsid–Stationary Phase Interactions Governing Native Stability and Chromatographic Separation Using AAV8 as a Model System

Pharmaceutics
Background/Objectives: Adeno-associated viruses (AAVs) are widely used gene therapy vectors; yet their physicochemical stability and chromatographic behavior are highly sensitive to the solution conditions they are in.
Timotej Žvanut, Mitja Martelanc, Aleš Štrancar, Andreja Gramc Livk   +3 more
doaj   +1 more source

Methodological considerations on the associations of serum CTRP3 and CysC with bone metabolism in elderly patients with T2DM

Journal of Diabetes Investigation, EarlyView.
Lijun Zhu, Bin Song
wiley   +1 more source

Evaluating School‐Based Obesity Prevention Interventions in 6‐ to 12‐Year‐Old Children: A Scoping Review of All Reported Outcomes and Expert Consultation

Obesity Reviews, EarlyView.
ABSTRACT Introduction This scoping review aims to identify all outcomes reported in school‐based obesity prevention interventions in childhood. It serves as an essential first step towards developing an internationally agreed‐upon Core Outcome Set (COS), which defines what should be measured in all school‐based childhood obesity prevention studies ...
Teatske M. Altenburg, Lotte W. de Vries, Iris J. Grooten, Janneke van 't Hooft, Arend W. van Deutekom, Tessa Roseboom, Erica van den Akker, Michael Duncan, Ulf Ekelund, John J. Reilly, Lisa Reilly, Annette Stafleu, Martyn Standage, Mai J. M. Chinapaw, Deirdre M. Harrington   +14 more
wiley   +1 more source

Beyond Deterministic Fetal Programming: Intrauterine Exposures and the Multifactorial Origins of Adiposity

Obesity Reviews, EarlyView.
ABSTRACT Excess adiposity is not a recently developed problem but has existed since at least the upper Paleolithic, allowing evolutionary selection pressures to adapt the physiology of the pregnant woman and the feto‐placental unit for maternal and fetal protection.
Gernot Desoye, Ursula Hiden, Evelyn Jantscher‐Krenn, Herbert Fluhr, Jonathan C. Wells, Sonja Entringer, Mireille N. M. van Poppel   +6 more
wiley   +1 more source

Reverse-phase chromatography removes double-stranded RNA, fragments, and residual template to decrease immunogenicity and increase cell potency of mRNA and saRNA

Molecular Therapy: Nucleic Acids
mRNA is produced by in vitro transcription reaction, which also leads to formation of immuno-stimulatory impurities, such as double-stranded RNA (dsRNA). dsRNA leads to activation of innate immune response linked to inhibition of protein synthesis.
Andreja Krušič, Nina Mencin, Marta Leban, Evelin Nett, Mario Perković, Ugur Sahin, Polona Megušar, Aleš Štrancar, Rok Sekirnik   +8 more
doaj   +1 more source

Maternal Overnutrition in Pregnancy Predicts Greater Body Mass Index Gains in Offspring by Early Midlife: A Systematic Review and Meta‐Analysis

Obesity Reviews, EarlyView.
ABSTRACT Maternal overnutrition during pregnancy predisposes children to increased adiposity later in life. This systematic review and meta‐analysis examined how this association persists into adulthood and whether it differs by sex. MEDLINE, EMBASE, Scopus, and CENTRAL were searched for human studies published in English before May 2025.
Szimonetta Eitmann, Péter Mátrai, Péter Hegyi, Márta Balaskó, Erika Pétervári   +4 more
wiley   +1 more source