Results 101 to 110 of about 3,089,076 (340)

Overview of Skin Whitening Agents: Drugs and Cosmetic Products

Cosmetics, 2016
Depigmentation and skin lightening products, which have been in use for ages in Asian countries where skin whiteness is a major esthetic criterion, are now also highly valued by Western populations, who expose themselves excessively to the sun and ...
Céline Couteau, Laurence Coiffard
doaj   +1 more source

Time, the final frontier

Molecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain, Michal Dibus, Omkar Joshi, Guillaume Jacquemet   +3 more
wiley   +1 more source

Laser-tracker-based reference measurement for geometric calibration of phase-measuring deflectometry with active display registration [PDF]

Journal of Sensors and Sensor Systems
Phase-measuring deflectometry (PMD) with active display registration (ADR) is a ray-optics-based technique for the shape measurement of specular surfaces.
Y. Sperling, R. B. Bergmann, R. B. Bergmann   +2 more
doaj   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

In-situ assessment of laser-chemically machined surfaces by means of an indirect optical measurement approach and scanning confocal fluorescence microscopy [PDF]

EPJ Web of Conferences
The manufacturing rate of laser-chemical machining (LCM) is limited to avoid disruptive boiling bubbles in the process fluid. Adjustments to e.g. the laser beam or the fluid properties can increase the removal rate. However, the existing understanding of
Niehaves Claudia, Bouraoui Yasmine, Radel Tim, Tausendfreund Andreas, Fischer Andreas   +4 more
doaj   +1 more source

PROBAST: A Tool to Assess the Risk of Bias and Applicability of Prediction Model Studies

Annals of Internal Medicine, 2019
Prediction relates to estimating the probability of something currently unknown. In the context of medical research, prediction typically concerns either diagnosis (probability of a certain condition being present but not yet detected) or prognosis ...
R. Wolff, K. Moons, R. Riley, P. Whiting, M. Westwood, G. Collins, J. Reitsma, J. Kleijnen, S. Mallett   +8 more
semanticscholar   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Effects of Short-Term Laser Beam Heating on the Absorptivity of Steel Sheets

Journal of Manufacturing and Materials Processing, 2019
The efficiency of laser beam processes basically depends on the efficiency of the laser beam source and the efficiency of the irradiated material’s energy absorption. This absorptivity can be influenced by the surface condition.
Helge Kügler
doaj   +1 more source

Characterisation of the role played by ELMO1, GPR141 and the intergenic polymorphism rs918980 in Fuchs' dystrophy in the Indian population

FEBS Open Bio, EarlyView.
This study reports the upregulation of ELMO1 and GPR141 in human Fuchs' endothelial corneal dystrophy (FECD) corneal endothelium and ultraviolet A‐induced FECD mice model. A genetic association of an intergenic single nucleotide polymorphism rs918980 present between both genes is observed with FECD in the Indian population.
Susmita Sharma, Samar Kumar Basak, Sujata Das, Debasmita Pankaj Alone   +3 more
wiley   +1 more source

Process Stability during Laser Beam Welding with Beam Oscillation and Wire Feed

Journal of Manufacturing and Materials Processing, 2019
Beam oscillation in laser material processing makes it possible to influence process behavior in terms of energy distribution, stability, melt pool dynamics and solidification.
Villads Schultz
doaj   +1 more source