Results 71 to 80 of about 2,029,317 (267)
In-situ assessment of laser-chemically machined surfaces by means of an indirect optical measurement approach and scanning confocal fluorescence microscopy [PDF]
EPJ Web of ConferencesThe manufacturing rate of laser-chemical machining (LCM) is limited to avoid disruptive boiling bubbles in the process fluid. Adjustments to e.g. the laser beam or the fluid properties can increase the removal rate. However, the existing understanding of
Niehaves Claudia +4 more
doaj +1 more source
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
Process Stability during Laser Beam Welding with Beam Oscillation and Wire Feed
Journal of Manufacturing and Materials Processing, 2019 Beam oscillation in laser material processing makes it possible to influence process behavior in terms of energy distribution, stability, melt pool dynamics and solidification.
Villads Schultz
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Multi-Cycle Process Signature of Laser-Induced Thermochemical Polishing
Journal of Manufacturing and Materials Processing, 2019 Laser-induced thermochemical polishing (LCP) is a non-conventional processing technique that uses laser radiation to smooth the surface of self-passivated metallic parts by initiating a localized anodic material dissolution.
Sandro Eckert
doaj +1 more source
Science, 2016 We all have it. Implicit bias was the shorthand that allowed our distant ancestors to make split-second decisions (friend or foe?) based on incomplete information. It provided a razor-thin reaction-time advantage that could mean life or death.
openaire +2 more sources
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source