Results 11 to 20 of about 6,035,490 (336)

A call to action to address critical flaws and bias in laboratory animal experiments and preclinical research [PDF]

open access: yesScientific Reports
During the design of hypothesis-driven, comparative laboratory animal experiments, investigators must control for cage effects, ensure full blinding and full randomization while adhering to established experimental designs, notably variations of the ...
Hugh G. G. Townsend   +9 more
doaj   +2 more sources

Demystifying inconsistent two-sample mendelian randomization estimations using selection diagram [PDF]

open access: yesBMC Medical Research Methodology
Two-Sample Mendelian Randomization (TSMR) analysis is a widely used method for inferring causal effect in the presence of unmeasured confounding. However, causal inferences may be biased if the distributions of key variables (e.g., exposures, outcomes ...
Lei Hou   +4 more
doaj   +2 more sources

Biased random k‐SAT [PDF]

open access: yesRandom Structures & Algorithms, 2021
AbstractThe basic random k‐SAT problem is: given a set of n Boolean variables, and m clauses of size k picked uniformly at random from the set of all such clauses on our variables, is the conjunction of these clauses satisfiable? Here we consider a variation of this problem where there is a bias towards variables occurring positive—that is, variables ...
Larsson, Joel, Markström, Klas
openaire   +4 more sources

Time Dependent Biased Random Walks [PDF]

open access: yesACM Transactions on Algorithms, 2022
We study the biased random walk where at each step of a random walk a “controller” can, with a certain small probability, move the walk to an arbitrary neighbour. This model was introduced by Azar et al. [STOC’1992]; we extend their work to the time dependent setting and consider cover times of this walk.
John Haslegrave   +2 more
openaire   +5 more sources

Biased random access codes

open access: yesPhysical Review A, 2023
A random access code (RAC) is a communication task in which the sender encodes a random message into a shorter one to be decoded by the receiver so that a randomly chosen character of the original message is recovered with some probability. Both the message and the character to be recovered are assumed to be uniformly distributed.
Gabriel Pereira Alves   +2 more
openaire   +2 more sources

Biased-Randomized Discrete-Event Heuristics for Dynamic Optimization with Time Dependencies and Synchronization

open access: yesAlgorithms, 2022
Many real-life combinatorial optimization problems are subject to a high degree of dynamism, while, simultaneously, a certain level of synchronization among agents and events is required.
Juliana Castaneda   +4 more
doaj   +1 more source

Random networks tossing biased coins [PDF]

open access: yesPhysical Review E, 2007
In statistical mechanical investigations on complex networks, it is useful to employ random graphs ensembles as null models, to compare with experimental realizations. Motivated by transcription networks, we present here a simple way to generate an ensemble of random directed graphs with, asymptotically, scale-free outdegree and compact indegree ...
F. Bassetti   +3 more
openaire   +6 more sources

Biased random walks on random combs [PDF]

open access: yesJournal of Physics A: Mathematical and Theoretical, 2007
We develop rigorous, analytic techniques to study the behaviour of biased random walks on combs. This enables us to calculate exactly the spectral dimension of random comb ensembles for any bias scenario in the teeth or spine. Two specific examples of random comb ensembles are discussed: the random comb with nonzero probability of an infinitely long ...
Tanya M Elliott, John F Wheater
openaire   +3 more sources

Mendelian randomization accounting for complex correlated horizontal pleiotropy while elucidating shared genetic etiology

open access: yesNature Communications, 2022
Mendelian randomization uses genetic variation to study the causal effect of exposure on outcome, but results can be biased by confounders, such as horizontal pleiotropy.
Qing Cheng   +3 more
doaj   +1 more source

Biased games on random boards [PDF]

open access: yesRandom Structures & Algorithms, 2014
ABSTRACTIn this paper we analyze biased Maker‐Breaker games and Avoider‐Enforcer games, both played on the edge set of a random board . In Maker‐Breaker games there are two players, denoted by Maker and Breaker. In each round, Maker claims one previously unclaimed edge of G and Breaker responds by claiming b previously unclaimed edges.
Ferber, Asaf   +3 more
openaire   +3 more sources

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