Results 21 to 30 of about 6,035,490 (336)
Randomizing a clinical trial in neuro-degenerative disease
Contemporary Clinical Trials Communications, 2023 The paper studies randomization rules for a sequential two-treatment, two-site clinical trial in Parkinson’s disease. An important feature is that we have values of responses and five potential prognostic factors from a sample of 144 patients similar to ...
Anthony C. Atkinson +3 more
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How Did CNBSS Influence Guidelines for So Long and What Can That Teach Us?
Current Oncology, 2022 The biased randomization and other quality concerns about the Canadian National Breast Screening Studies (CNBSS) were documented and criticized for decades, even by several individuals very close to the research.
Shushiela Appavoo
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Color‐biased Hamilton cycles in random graphs
Random Structures & Algorithms, 2021 AbstractWe prove that a random graph , with p above the Hamiltonicity threshold, is typically such that for any r‐coloring of its edges there exists a Hamilton cycle with at least edges of the same color. This estimate is asymptotically optimal.
Gishboliner, Lior +2 more
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A Biased-Randomized Iterated Local Search Algorithm for Rich Portfolio Optimization
Applied Sciences, 2019 This research develops an original algorithm for rich portfolio optimization (ARPO), considering more realistic constraints than those usually analyzed in the literature. Using a matheuristic framework that combines an iterated local search metaheuristic
Renatas Kizys +3 more
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Limited evidence for blood eQTLs in human sexual dimorphism
Genome Medicine, 2022 Background The genetic underpinning of sexual dimorphism is very poorly understood. The prevalence of many diseases differs between men and women, which could be in part caused by sex-specific genetic effects.
Eleonora Porcu +11 more
doaj +1 more source
Biased Random Walk on the Trace of Biased Random Walk on the Trace of … [PDF]
Communications in Mathematical Physics, 2019 We study the behaviour of a sequence of biased random walks X(i), i>=0 on a sequence of random graphs, where the initial graph is Zd and otherwise the graph for the i-th walk is the trace of the (i - 1)-st walk. The sequence of bias vectors is chosen so that each walk is transient.
Croydon, D, Holmes, M
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Biased random walks and propagation failure [PDF]
Physical Review E, 2007 The critical value of the reaction rate able to sustain the propagation of an invasive front is obtained for general non-Markovian biased random walks with reactions. From the Hamilton-Jacobi equation corresponding to the mean field equation we find that the critical reaction rate depends only on the mean waiting time and on the statistical properties ...
Méndez, Vicenç +3 more
openaire +6 more sources
The need for randomization in animal trials: an overview of systematic reviews. [PDF]
PLoS ONE, 2014 Background and objectivesRandomization, allocation concealment, and blind outcome assessment have been shown to reduce bias in human studies. Authors from the Collaborative Approach to Meta Analysis and Review of Animal Data from Experimental Studies ...
Jennifer A Hirst +6 more
doaj +1 more source
An Easily Accessible Web-Based Minimization Random Allocation System for Clinical Trials
Journal of Medical Internet Research, 2013 BackgroundMinimization as an adaptive allocation technique has been recommended in the literature for use in randomized clinical trials.
Xiao, Lan +3 more
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Nature Communications, 2020 Estimates from Mendelian randomization studies of unrelated individuals can be biased due to uncontrolled confounding from familial effects. Here we describe methods for within-family Mendelian randomization analyses and use simulation studies to show ...
B. Brumpton +51 more
semanticscholar +1 more source