Results 61 to 70 of about 6,035,490 (336)

A variable neighborhood search simheuristic for project portfolio selection under uncertainty [PDF]

open access: yes, 2018
With limited nancial resources, decision-makers in rms and governments face the task of selecting the best portfolio of projects to invest in. As the pool of project proposals increases and more realistic constraints are considered, the problem becomes
Döering, Jana   +4 more
core   +1 more source

Biased random walks on the interlacement set [PDF]

open access: yesAnnales de l'Institut Henri Poincaré, Probabilités et Statistiques, 2018
We study a biased random walk on the interlacement set of $\mathbb{Z}^d$ for $d\geq 3$. Although the walk is always transient, we can show, in the case $d=3$, that for any value of the bias the walk has a zero limiting speed and actually moves slower than any power.
Fribergh, Alexander, Popov, Serguei
openaire   +4 more sources

Efficacy and Tolerability of Topotecan/Cyclophosphamide/Dinutuximab in Relapsed and Refractory High‐Risk Neuroblastoma: A Multi‐Institutional Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Chemoimmunotherapy with irinotecan, temozolomide, and dinutuximab (I/T/DIN) has emerged as first‐line therapy for relapsed/refractory (r/r) high‐risk neuroblastoma (HRNB) in North America. Topotecan and cyclophosphamide (T/C) are often used in combination with dinutuximab in the setting of lack of response, progression, or incomplete ...
Benjamin J. Lerman   +17 more
wiley   +1 more source

Crowding effects in vehicular traffic [PDF]

open access: yes, 2012
While the impact of crowding on the diffusive transport of molecules within a cell is widely studied in biology, it has thus far been neglected in traffic systems where bulk behavior is the main concern.
Combinido, Jay Samuel L., Lim, May T.
core   +3 more sources

A biased-randomized iterated local search for the vehicle routing problem with optional backhauls

open access: yesTOP - An Official Journal of the Spanish Society of Statistics and Operations Research, 2020
The vehicle routing problem with backhauls integrates decisions on product delivery with decisions on the collection of returnable items. In this paper, we analyze a scenario in which collection of items is optional—but subject to a penalty cost.
Julio C. Londoño   +3 more
semanticscholar   +1 more source

Experimental Design in Two-Sided Platforms: An Analysis of Bias [PDF]

open access: yesACM Conference on Economics and Computation, 2020
We develop an analytical framework to study experimental design in two-sided platforms. In the settings we consider, customers rent listings; rented listings are occupied for some amount of time, then become available.
Ramesh Johari, Hannah Li, G. Weintraub
semanticscholar   +1 more source

Biased landscapes for random constraint satisfaction problems [PDF]

open access: yesJournal of Statistical Mechanics: Theory and Experiment, 2019
32 pages, 16 ...
Budzynski, Louise   +2 more
openaire   +4 more sources

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

A simheuristic algorithm for solving an integrated resource allocation and scheduling problem [PDF]

open access: yes, 2019
Modern companies have to face challenging configuration issues in their manufacturing chains. One of these challenges is related to the integrated allocation and scheduling of resources such as machines, workers, energy, etc.
Ferone, Daniele   +4 more
core   +1 more source

Within family Mendelian randomization studies.

open access: yesHuman Molecular Genetics, 2019
Mendelian randomization (MR) is increasingly used to make causal inferences in a wide range of fields, from drug development to aetiologic studies. Causal inference in MR is possible because of the process of genetic inheritance from parents to offspring.
N. Davies   +5 more
semanticscholar   +1 more source

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