Results 101 to 110 of about 679,735 (317)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Frontiers in Virtual RealityThanks to generative artificial intelligence, autonomous AI agents are set to populate the emerging metaverse–understood here as persistent, interoperable, immersive digital environments encompassing existing gaming platforms and emerging spatial ...
Anselm Küsters
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Self-reported cognitive biases in depression: A meta-analysis
, 2020 Despite the influence of Beck's cognitive models of depression, the presence and magnitude of the specific proposed cognitive biases have not been systematically investigated.
Robles, Elena +2 more
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Market feedback does not eliminate biases in the perception of independence
, 2009 In individual decision making experiments I test the robustness of biases in the perception of independence and whether they survive feedback about the median decision in groups of five.
Fischer, S.
core
The impact of top-down factors on threat perception biases in health and anxiety
, 2020 The perception of threat is important for survival and is therefore perceptually prioritized. This prioritization has largely been studied as a stimulus-driven (i.e., bottom-up) process.
Jin, JF +5 more
core +1 more source
Personality biases in different types of 'internet samples' can influence research outcomes [PDF]
, 2018 There are different ways of recruiting participants for internet-mediated research. Small differences in personality have previously been documented between participants recruited in different ways.
Buchanan, T.
core +1 more source
The Inclusion of Metacognition in Source Evaluation Instruction
Communications in Information LiteracyThough the ACRL Framework holds metacognition as crucial to exercising information literacy, its emphasis was reduced from prominence in early drafts to a single mention in the final document. At the same time, few of the frequently-taught sets of source
Anthony Tardiff
doaj +1 more source