Results 181 to 190 of about 5,744 (242)

Macrophage‐derived galectin‐3 contributes to pyroptosis, apoptosis and necroptosis through TLR4/MyD88/NF‐κB/NLRP3 during atherosclerosis

open access: yesClinical and Translational Medicine, Volume 16, Issue 3, March 2026.
Pyroptosis, apoptosis and necroptosis of macrophages occur concurrently during atherosclerosis. Galetein‐3 and NLRP3 are highly expressed in atherosclerotic lesions. Galectin‐3 is principally expressed in macrophages within atherosclerotic plaques. Galectin‐3 interacts with NLRP3, activates TLR4/MyD88/NF‐κB/NLRP3 signal axis, and promotes PANoptosis ...
Zihui Yuan   +5 more
wiley   +1 more source

Combined Vertical and Horizontal Components of Near‐Source Earthquakes and Impact on Base‐Isolated Structures

open access: yesEarthquake Engineering &Structural Dynamics, Volume 55, Issue 3, Page 781-803, March 2026.
ABSTRACT Over recent decades, the collection of seismic data has improved the understanding of near‐fault ground motion effects, which involve both horizontal and vertical components. Among the most significant effects are fault‐normal directivity, which concentrates seismic energy into an intense, long‐period pulse, and fault‐parallel fling step ...
Giulia Giuliani   +7 more
wiley   +1 more source

Failure Mechanism of Asymmetric Large Deformations Under Repeated Mining in Roadways

open access: yesEnergy Science &Engineering, Volume 14, Issue 3, Page 1195-1212, March 2026.
Principal stress‐evolution diagram at different advance positions of 42205 working face. ABSTRACT To address the challenge of controlling severe asymmetrical deformation in roadways subjected to repeated mining, this study (i.e., based on the engineering context of the Buertai Coal Mine) investigated the characteristics of the regional stress field in ...
Ai‐Rong Wang   +3 more
wiley   +1 more source

Fiber‐Reinforced Composites for Vaginal Tissue Engineering Applications

open access: yesJournal of Biomedical Materials Research Part A, Volume 114, Issue 3, March 2026.
ABSTRACT The vagina is a fibromuscular tube‐shaped organ that plays critical roles in menstruation, pregnancy, and female sexual health. Vaginal tissue constituents, including cells and extracellular matrix components, contribute to tissue structure, function, and prevention of injury and pathology.
Samyuktha S. Kolluru   +6 more
wiley   +1 more source

Combined Flexion, Torsion and Compression Drive Distinct Intervertebral Disc Failure Mechanisms Under Asymmetric, High‐Cycle Loading

open access: yesJOR SPINE, Volume 9, Issue 1, March 2026.
Using advanced multiaxial bioreactor systems, this study investigated the effects of flexion, torsion, and static compression on whole intervertebral discs. High cycle asymmetric loading resulted in cell death in the nucleus pulposus and structural changes in the annulus fibrosus.
Amra Šećerović   +8 more
wiley   +1 more source

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