Results 231 to 240 of about 248,353 (282)
PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao +16 more
wiley +1 more source
Understanding vaccine hesitancy: Insights from social media on polio, human papilloma virus, and COVID-19 in Zambia. [PDF]
Munjita SM.
europepmc +1 more source
Thermal Plasticity is Regulated by a Key MicroRNA During Range Expansion of an Invasive Fruit Fly
Populations at the invasion front of Bactrocera dorsalis adapt through reduced phenotypic and gene expression plasticity, a phenomenon likely to be driven by genetic assimilation. We identify a key miRNA‐mediated regulatory axis, in which miR‐276b post‐transcriptionally represses thw, a conserved chitin‐binding gene critical to the cold‐tolerance ...
Yan Zhao +5 more
wiley +1 more source
Use of Epoetin Alfa for Anemia of Chronic Disease in a Jehovah's Witness Teenager With Disseminated Coccidioidomycosis: A Case Report. [PDF]
Ozaki Y, Herrmann D.
europepmc +1 more source
A large‐scale, high‐resolution antimicrobial resistance (AMR) surveillance in Hong Kong community sewage combining short‐ and long‐read sequencing. The resistome profile is comprehensively characterized, and this upstream sampling strategy demonstrated superiority in reflecting the human gut resistome.
Jiahui Ding +11 more
wiley +1 more source
The "Writing on the Wall Maneuver" Reveals the Dystonic Nature of Primary Writing Tremor. [PDF]
Erro R +4 more
europepmc +1 more source
Ectodermal tissue excised from Xenopus embryos self‐organizes into a three‐dimensional mucociliary organoid. Here, we generate a neural variant, termed neurobot, by implanting neural precursor cells. Neurobots develop mature neurons, adopt distinct morphologies, exhibit more complex motility, and respond differentially to neuroactive compounds. Imaging
Haleh Fotowat +6 more
wiley +1 more source
Underpinnings of the Halachic Approach to BRCA Screening and Intervention: Facilitating Provider Counseling for Observant Jewish Populations. [PDF]
Greenberger C, Mor P.
europepmc +1 more source

