Results 161 to 170 of about 2,254,420 (373)

Germline pathogenic variants in HIC1 DNA binding domains are associated with familial serrated polyposis syndrome

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Serrated polyposis syndrome has been associated with an increased risk of colorectal cancer. HIC1 is a tumor suppressor gene commonly silenced in serrated polyps and several cancers. This study suggests HIC1 as a novel germline predisposition factor to serrated polyposis syndrome, with variants altering gene transcriptional regulation and ...
Xavier Domínguez‐Rovira   +24 more
wiley   +1 more source

Green banks versus non‐green banks: A financial stability comparative analysis in terms of CAMEL ratios

open access: yesInternational Journal of Finance &Economics, EarlyView.
Abstract This study examines green and non‐green‐banks from a financial stability point of view and specifically whether there are any discernible performance differences between the two groups. Using the supervisory ratios namely CAMEL variables, and employing panel data techniques (random effects model) and a global panel data set of 165 banks from ...
Ioannis Malandrakis, Konstantinos Drakos
wiley   +1 more source

Major Conundrums and Possible Solutions in DeFi Insurance

open access: yesInternational Journal of Finance &Economics, EarlyView.
ABSTRACT This paper empirically explores the early development of insurance projects in the decentralised finance (DeFi) industry, which is based on disruptive technologies like blockchain and smart contracts. A brief history of DeFi is narrated, stressing four risks of DeFi (volatility risk, cyberattack risk, liquidity risk, and regulation risk) and ...
Peng Zhou, Ying Zhang
wiley   +1 more source

Prevention of RhD alloimmunization in the first trimester of pregnancy: Clinical practice guidelines of the French College of Obstetricians and Gynecologists

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract The French College of Obstetricians and Gynecologists has decided to update its clinical practices guidelines for preventing RhD alloimmunization in the first trimester of pregnancy. The quality of evidence of the literature was assessed following the GRADE methodology with questions formulated in the Patients, Intervention, Comparison ...
Paul Maurice   +4 more
wiley   +1 more source

Enhancing human gut health: Global innovations in dysbiosis management

open access: yesiMeta, EarlyView.
The microbiota, comprising all the microorganisms within the body, plays a critical role in maintaining good health. Dysbiosis represents a condition resulting from an imbalance or alteration of the microbiota. This study comprehensively investigates the patent literature on dysbiosis over the past 20 years.
Reda El Boukhari   +66 more
wiley   +1 more source

Toxicological Response of the BEAS‐2B Cell After Acute Exposure at the Air–Liquid Interface to Ethylbenzene and m‐Xylene Alone and in Binary Mixtures

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Benzene, toluene, ethylbenzene, and xylenes (o‐, m‐, and p‐xylenes) constitute a family, named BTEX, of volatile organic compounds (VOCs) known for its toxicity. This study aimed to study the acute in vitro toxicity of ethylbenzene and m‐xylene on human bronchial epithelial cells exposed at the air–liquid interface (ALI).
Nour Jaber   +3 more
wiley   +1 more source

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