Results 161 to 170 of about 236,506 (251)

Chloride at the spotlight-but not alone: towards a multi-ionic diuretic strategy. [PDF]

Clin Kidney J
Montomoli M, Gil Martins Roxo MI, González-Rico M, Núñez J, Núñez-Marín G, Uriarte BA, De La Espriella R, Puchades MJ, Górriz JL.   +8 more
europepmc   +1 more source

Magnetic lipase B from Candida antarctica (CALB) biocatalyst for integrated valorization of tilapia by‐products and biodiesel biorefining

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract The immobilization of lipase B from Candida antarctica (CALB) on an amino‐epoxy functionalized magnetic support (Fe3O4‐PEI‐DGEBA) resulted in a highly stable and efficient biocatalyst for biofuel production from tilapia oil. The synthesized support was characterized using scanning electron microscopy, transmission electron microscopy, X‐ray ...
Rafael Leandro Fernandes Melo, Francisco Simão Neto, Bruno Caio Chaves Fernandes, Paulo Gonçalves de Sousa Junior, Patrick da Silva Sousa, Tiago Melo Freire, Raniere Dantas Valença, Frederico Ribeiro do Carmo, Marcos Reinaldo da Silva, Leonardo Farias Serafim, João Maria Soares, Pierre Basílio Almeida Fechine, José Cleiton Sousa dos Santos   +12 more
wiley   +1 more source

Systemic Salicylate Toxicity From Topical Emollient Use in an Infant With Suspected Ichthyosis. [PDF]

Cureus
Pullukat K, Husien T.
europepmc   +1 more source

Pregnancy‐related effect on elexacaftor, tezacaftor and ivacaftor pharmacokinetics in women with cystic fibrosis

British Journal of Clinical Pharmacology, EarlyView.
Aim The number of pregnancies among women with cystic fibrosis (wwCF) has steadily increased over the past decade. However, the pharmacokinetics (PK) of elexacaftor–tezacaftor–ivacaftor (ETI) during gestation remains uncharacterized, despite its widespread use in this population.
Paulette Magnas, Naim Bouazza, Frantz Foissac, Saïk Urien, Léo Froelicher‐Bournaud, Gabrielle Lui, Victoria Guillemart, Nicolas Carlier, Jennifer Da Silva, Johanna Fesenbeckh, Reem Kanaan, Isabelle Honoré, Clémence Martin, Jean‐Marc Treluyer, Vassilis Tsatsaris, Pierre‐Régis Burgel, Sihem Benaboud   +16 more
wiley   +1 more source

Evaluation of a pantoprazole and 4‐desmethylpantoprazole‐sulfate metabolic ratio as a novel CYP2C19 phenotyping method

British Journal of Clinical Pharmacology, EarlyView.
Aims CYP2C19 is one of the most important pharmacogenes, and its activity is highly variable due to factors such as genetics or drug–drug interactions. Due to the lack of an appropriate endogenous CYP2C19 biomarker, surrogate methods to assess its activity are warranted.
Julian Peter Müller, Vladimir N. Belov, Sabrina Yamoune, Bob Miller, Mohammed Hasoumi, Jolanta Tupiec, Thea Laurentius, L. Cornelius Bollheimer, Julia C. Stingl, Katja S. Just   +9 more
wiley   +1 more source

The Role of Bicarbonate Therapy in Diabetic Ketoacidosis: A Systematic Review and Meta-Analysis. [PDF]

Endocrinol Diabetes Metab
Omayer A, Kc A, Sharif A, Hoque SMH, BaniHani H, Khaled L, Sajjad W, Nassar M, Holeihel A.   +8 more
europepmc   +1 more source

One‐Pot Synthesis of a Small Synthetic Ligand for Antibody Purification

Biotechnology and Bioengineering, EarlyView.
One‐pot liquid‐phase synthesis of the synthetic ligand B1Al2A2 enables controllable ligand density and efficient capture of IgG and IgY with high recovery and purity, streamlining small‐ligand affinity purification workflows. ABSTRACT The development of synthetic affinity ligands offers a cost‐effective alternative to traditional biological ligands ...
Carolina Mota Natal, Catarina Domingos, André Nascimento, José Mendes, Afonso B. Ruiz, Ana Margarida Gonçalves Carvalho Dias, Luisa M. Ferreira, Cristina Peixoto, Ana Cecília Afonso Roque   +8 more
wiley   +1 more source

Severe Diabetic Ketoacidosis With Extreme Acidemia and Preserved Consciousness: Intensive Care Management Guided by Pathophysiology Without Bicarbonate or Intubation. [PDF]

Cureus
Filippelli OSG, Procopio D, Giglio AM, Pezzi M, Faragò S.   +4 more
europepmc   +1 more source

Metabolic Flux Analysis Reveals Cell Line‐Specific Rewiring in CHO Cells Following TCA Cycle Intermediate Feeding for Bioprocess pH Control

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Chinese hamster ovary (CHO) cells are the leading host for recombinant therapeutic protein production in the biopharma industry. In this study, we investigated how feeding acidic forms of tricarboxylic acid (TCA) cycle intermediates—malic acid, succinic acid, and α‐ketoglutaric acid—affects cell culture performance and metabolism in two ...
Sarah A. Sacco, Kevin J. Ruiz‐Márquez, Rachel Moen, Irina Trenary, Xiaolin Zhang, Xiaowen Wang, Malik Padellan, Henry Lin, Jamey D. Young   +8 more
wiley   +1 more source