Results 141 to 150 of about 6,433 (249)

Autoantibodies to Extracellular Erythrocyte Band 3 Epitopes Are Associated With Anemia in Plasmodium vivax Infection

American Journal of Hematology, EarlyView.
ABSTRACT Plasmodium vivax‐associated anemia is a multifactorial clinical outcome, in which the destruction of uninfected red blood cells (uRBCs) plays a major role in disease development and severity. Here, we identified autoantibody targets within the extracellular loops of Band 3 (B3), a major erythrocyte transmembrane protein.
Aline Marzano‐Miranda, Vanessa G. Fraga, Cor Jésus F. Fontes, Simone Ladeia‐Andrade, Marcelo U. Ferreira, Daniella C. Bartholomeu, Érika M. Braga   +6 more
wiley   +1 more source

Beyond Canonical CO Oxidation: Structural and Evolutionary Insights Into a Non‐Canonical Carbon Monoxide Dehydrogenase

Angewandte Chemie, EarlyView.
Clade B carbon monoxide dehydrogenases (CODHs) remain enigmatic, diverging from canonical CODHs in structure and function. Here, we present the first characterization of Ruminococcus flavefaciens CODH (RfCODH), revealing occluded substrate pathways and attenuated CO oxidation activity.
Maximilian Böhm, Vivek Srinivas, Benjamin Wiseman, Ping Huang, Moritz Senger, Martin Högbom, Henrik Land   +6 more
wiley   +2 more sources

Histidine Supplementation Stabilizes Hearing and Vision and Improves Growth in HARS1‐Related Autosomal Recessive Disorder Associated With Usher‐Like Symptoms

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autosomal recessive HARS1‐related disorder (originally described as Usher syndrome type 3B) caused by a homozygous Y454S variant in the histidyl‐tRNA synthetase gene (HARS1) is characterized by progressive sensorineural hearing and vision loss and respiratory deterioration with risk for sudden death following febrile illnesses.
Victoria Mok Siu, Rosan Kenana, Rana Chakrabarti, Sarah D. P. Wilhelm, Joseph Andrews, Susan J. Leat, Christina Parker, Michael Miller, Leslie A. Nangle, Wendy McCaul, Ashfia Chowdhury, Natalie Hutchings, Ryan A. Adams, Lauren Guy, Mandy Rhody, Verena Juncal, Marisa I. Mendes, Desiree E. C. Smith, Gajja S. Salomons, Angelica A. Moresco, Daphne L. McCulloch, D. Holmes Morton, Ilka U. Heinemann, C. Anthony Rupar   +23 more
wiley   +1 more source

CO2‐to‐CO Electrochemical Conversion With an Fe(I) Porphyrin Complex in Water

Angewandte Chemie, EarlyView.
Using in situ UV–vis/IR spectroelectrochemistry, we track CO2 reduction by a water‐soluble iron porphyrin. Rather than the usual [Fe0] intermediate in organic solvents, CO2 binds the electrogenerated [FeI] species and undergoes reductive C─O cleavage to stable [FeII‐CO]. This previously unexplored reaction pathway is facilitated by an aqueous H‐bonding
Andrew Howe, Aude Salamé, Ulysse Garnier, Marc Robert, Elodie Anxolabéhère‐Mallart, Mun Hon Cheah   +5 more
wiley   +2 more sources

Licorice-Induced Pseudohyperaldosteronism Highlights an Underestimated Etiology of Hypertension. [PDF]

Kidney Int Rep
Bendjilali-Sabiani JJ, Cardinale A, Lamy A, Pouget AM, Boyer JC, Taillard V, Reboul P.   +6 more
europepmc   +1 more source

Distribution of Big Tau Isoforms in the Human Central and Peripheral Nervous System

Annals of Neurology, EarlyView.
Objective Tau is widely studied in neurodegeneration, yet most work has focused on canonical brain tau isoforms. A longer isoform, “big tau,” produced by inclusion of exon 4a, is expressed in the peripheral nervous system (PNS) and central nervous system (CNS) regions.
Rama Krishna Koppisetti, Nicolas R. Barthélemy, Kanta Horie, Cindy V. Ly, Kaleigh F. Roberts, Srinivas Koutarapu, Richard J. Perrin, Erin E. Franklin, Chiara Pedicone, Joshua Orrick, Justin Melendez, Timothy M. Miller, Chihiro Sato, Nupur Ghoshal, Alison M. Goate, Celeste M. Karch, Randall J. Bateman, Soumya Mukherjee   +17 more
wiley   +1 more source

Randomized preclinical study of machine perfusion in vascularized composite allografts

BJS (British Journal of Surgery), EarlyView., 2020
This study was designed to identify the optimum machine perfusion parameters for preservation of limbs before transplantation, and determine whether this was better than cold storage. Normothermic machine perfusion at a pressure of 70 mmHg (NMP‐70) provided superior preservation to cold storage after transplantation.
K. R. Amin, J. P. Stone, J. Kerr, A. Geraghty, L. Joseph, A. Montero‐Fernandez, J. K. Wong, J. E. Fildes   +7 more
wiley   +1 more source

The Role of Zn–Hf Site Proximity and Oxygen Vacancies for Methanol Formation Over ZnHfOx Catalysts Under CO2 Hydrogenation Conditions

Angewandte Chemie, EarlyView.
ZnHfOx catalysts enable highly selective hydrogenation of CO2 to methanol over a wide range of Zn contents, as the Zn‐VO‐Hf active motif (VO = oxygen vacancy) exists not only in solid solution‐type ZnHfOx for low Zn contents (≤ 35 mol%), but also as HfOx cluster/single atom decorated ZnO surfaces for Zn contents > 95 mol%.
Alexander Oing, Diana Piankova, Jean C. Villa‐Arpi, Muhammad Helmi Risansyauqi, Hector Prats, Felix Donat, Paula M. Abdala, Aleix Comas‐Vives, Christoph R. Müller   +8 more
wiley   +2 more sources

Editorial: Retroconstruction of porous crystalline networks for a sustainable future. [PDF]

Front Chem
Li X.
europepmc   +1 more source

Synergy Between Photon‐to‐Phonon Pathway and Active Lattice Oxygen Enables Efficient and Stable Syngas Synthesis

Angewandte Chemie, EarlyView.
This work reports the design of a multifunctional MnOx support coupled with classic Rh catalytic centers for light‐driven dry reforming of methane. Benefiting from efficient photon‐to‐phonon conversion pathway and a dynamic OL‐OV cycle, the catalyst achieves high syngas production rates and light‐to‐chemical energy efficiency without external heating ...
Chengzhi Guo, Apoorv Jain, Junrun Feng, Xinyu Li, Xinru Li, Shuya Jia, Juncong Wang, Leirun Chen, Xinjie Luo, Xiaolei Zhang, Xiyi Li, Yang Lan   +11 more
wiley   +2 more sources