Results 141 to 150 of about 8,373 (286)

Multimodal Imaging of Hypoxia, Metabolism and pH in Feline Sarcoma Using Hyperpolarized 13C MRI and PET

Advanced Science, EarlyView.
This work presents a clinically deployable simultaneous PET/MRI workflow which integrates hyperpolarized 13C imaging of metabolism and extracellular pH with [18F]FMISO PET to characterize hypoxia, acidosis, and metabolic reprogramming in feline sarcoma.
Martin Grashei, Tanja Groll, Stephanie Kahl, Silke Baer, Elisabeth Bliemsrieder, Frits H. A. van Heijster, Andre Wendlinger, Pascal Wodtke, Jorge Cabello, Susan Notohamiprodjo, Christian Lohrmann, Markus Schwaiger, Wolfgang A. Weber, Katja Steiger, Andrea Meyer‐Lindenberg, Johannes Hirschberger, Christine Baumgartner, Franz Schilling   +17 more
wiley   +1 more source

Efficacy, Safety, and Tolerability of Nasal Wash in Patients with Upper Respiratory Tract Diseases

International Archives of Otorhinolaryngology
Ignazio La Mantia, Giovanna Stilo, Lepanto Lentini, Giorgio Ciprandi   +3 more
doaj   +1 more source

Smartphone‐Guided Visible Light Modulation of RSNOs for Antimicrobial Activity via Controlled Nitric Oxide Release

Advanced Science, EarlyView.
A light‐activated catheter insert combines antimicrobial blue light with nitric oxide release to generate complementary oxidative and nitrosative stress, producing potent broad‐spectrum antimicrobial activity. The approach achieves greater than 4‐log reductions in bacterial and fungal viability and significantly reduces Staphylococcus aureus ...
Alexander Bruckmann, Adam Brooks Goodman, Myddelton C. Parker, Mark Garren, Ji Eun Park, Chad Schmiedt, Hitesh Handa, Elizabeth J. Brisbois   +7 more
wiley   +1 more source

Growth of <i>Limnospira platensis</i> Under Elevated CO₂ with the Addition of Sodium Selenite. [PDF]

Plants (Basel)
Grigorenko AV, Kovalenko EM, Vavilkina ME, Kravets MA, Vlaskin MS.   +4 more
europepmc   +1 more source

The Deubiquitinase UCHL1 Drives Susceptibility to Atrial Fibrillation by Stabilizing CaMKII‐δ

Advanced Science, EarlyView.
UCHL1 is highly upregulated in mice and patients with AF. UCHL1 directly binds to and removes K48‐linked polyubiquitin chains from CaMKII‐δ at K251 and enhances CaMKII‐δ stability, which activates RyR2, disrupts Ca2+ handling, and promotes AF. These findings establish UCHL1 as a critical regulator of CaMKII‐δ stability and AF‐related Ca2+ handling ...
Hai‐Lian Bi, Yu‐Hui Gu, Kai‐Wen Ren, Xiao‐Hong Yu, Yun‐Long Xia, Xiao‐Lei Yang, Hui‐Hua Li   +6 more
wiley   +1 more source

Kidney Pathology of Megalin Deficiency in Adulthood. [PDF]

Kidney Med
Cassard A, Colombat M, Perier T, Schanstra J, Faguer S.   +4 more
europepmc   +1 more source

Nascent Extracellular Matrix Converts Biomaterial Cues into Cell Fate Decisions

Advanced Science, EarlyView.
This study uncovers a tri‐directional interplay among cells, hydrogels, and their nascent extracellular matrix. Hydrogel norbornene modification alters CD44‐mediated cell–hydrogel interactions, which shape nascent matrix deposition, composition, and spatial organization.
Joshua Y. Liu, Ziqian Yang, Arina E. Velieva, Eleanor M. Plaster, Mingyue Fan, Donia W. Ahmed, Avinava Roy, Pamela Duran, Pamela Panovich, Alexandra S. Piotrowski‐Daspit, Carlos A. Aguilar, Megan L. Killian, Claudia Loebel   +12 more
wiley   +1 more source

Pt‐Regulated Dynamic Cu(0) Regeneration in CuPt Alloy Enables High‐Efficiency Self‐Driven Formaldehyde Fuel Cells for Potassium Formate Production

Advanced Science, EarlyView.
In this work, a Cu30PtX/CF anode material was synthesized to effectively catalyze the electrocatalytic formaldehyde oxidation, and thereby assembled a fuel cell that offered a high open‐circuit potential of 0.94 V and a power density of 34.3 mW cm−2. This work realizes the co‐generation of electrical energy and high‐value‐added chemicals with nearly ...
Hanxu Hou, Yan Zhou, Weixiang Tang, Desheng Sui, Siman Tao, Xiaohan Li, Hui Zhang, Jiawei Qiang, Wenle Li, Jun Zhang   +9 more
wiley   +1 more source

Acidosis at Diagnosis of Type 1 Diabetes Mellitus: Relation With Kidney Function. [PDF]

Pediatr Diabetes
Guarino S, Iafusco D, Di Sessa A, Tirelli P, Rivetti G, Ippolito G, Bartiromo M, Cirillo G, Zanfardino A, Miraglia Del Giudice E, Marzuillo P.   +10 more
europepmc   +1 more source

Oral Recombinant Human Collagen III Protects Gastric Mucosa via G‐Quadruplex‐Mediated Activation of the Pla2g4a‐Prostaglandin Axis

Advanced Science, EarlyView.
Orally administered recombinant human type III collagen protects the gastric mucosa from ethanol‐induced injury by coordinating redox homeostasis, epithelial barrier repair, and arachidonic acid–prostaglandin metabolism. Gastric digestion releases the pentapeptide GPAEF, which interacts with the Pla2g4a promoter G‐quadruplex in a structure‐dependent ...
Xinyue Lan, Qiu Dai, Yanhui Wang, Jiaxuan Gu, Chengyun Wang, Weicheng Xu, Xinru Gao, Jiageng Cheng, Wentao Geng, Xiaowen Wu, Haihang Li, Xiaoyun He, Shengwei Fu, Longjiao Zhu, Wentao Xu   +14 more
wiley   +1 more source