Results 41 to 50 of about 17,030 (279)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Ménage-à-trois: The ratio of bicarbonate to CO2 and the pH regulate the capacity of neutrophils to form NETs

Frontiers in Immunology, 2016
In this study we identified and characterized the potential of a high ratio of bicarbonate to CO2 and a moderately alkaline pH to render neutrophils prone to undergo neutrophil extracellular trap (NET) formation.
Christian Maueröder, Aparna Siddharth Mahajan, Susanne Paulus, Stefanie Nowecki, Jonas Hahn, Deborah Kienhöfer, Mona Helena Biermann, Philipp Tripal, Ralf Philipp Friedrich, Luis Enrique Munoz, Markus F Neurath, Christoph Becker, Georg Andreas Schett, Martin Herrmann, Moritz Leppkes   +14 more
doaj   +1 more source

Control of apple scab by curative applications of biocontrol agents [PDF]

, 2008
In organic apple growing protective applications with copper, sulphur or lime sulphur are used for apple scab control. Protective applications have to be repeated when new leaves unfold.
Hinze, M., Kunz, S., Mögel, G., Volk, F.   +3 more
core  

Bilan du carbone dans le lagunage anaérobie appliqué sous climat méditerranéen [PDF]

, 2003
Ce travail a porté sur l'application du lagunage anaérobie pour le traitement primaire des eaux résiduaires urbaines sous climat méditerranéen. Il a été réalisé sur les lagunes anaérobies de l' Ecosite de Mèze (Hérault, France).
Costa, R., Paing, J., Picot, B., Rambaud, A., Sambuco, J.-P.   +4 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

The assessment of water quality in river Molo water basin, Kenya

Applied Water Science, 2020
The monitoring of water quality for both domestic and commercial use is absolutely essential for policy formulation that affects both public and environmental health.
Emily B. Chebet, Joshua K. Kibet, Damaris Mbui   +2 more
doaj   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Determinants and Characteristics of Insulin Dose Requirements in Children and Adolescents with New-Onset Type 1 Diabetes: Insights from the INSENODIAB Study

Journal of Diabetes Research, 2023
Aims. New-onset type 1 diabetes mellitus (T1D) in pediatric patients represents a clinical challenge for initial total daily insulin dosing (TIDD) due to substantial heterogeneity in practice and lack of consensus on the optimal starting dose.
Maude Beckers, Olivier Polle, Paola Gallo, Noémie Bernard, Céline Bugli, Philippe A. Lysy   +5 more
doaj   +1 more source

Correlation of planktonic biomass with other physico-chemical parameters of water quality in fertilized fish ponds

International Journal of Applied and Experimental Biology, 2022
The production of common carp (Cyprinus carpio) was studied in pond fertilized with cow-dung @ 0.1g N/10g in the presence of planktonic biomass. The correlation of planktonic biomass with water quality physicochemical parameters of three fish ponds, was ...
Fayyaz Rasool, Shakeela Parveen, Matiullah, Kashif Manzoor, Shahid Mahmood   +4 more
doaj   +1 more source

Temporal changes in carboxylate content of ryegrass with stepwise change in nutrition [PDF]

A detailed scheme of carboxylate formation and retention by plant tissues as a result of ion uptake and utilization is given. By means of discontinuities in the supply with nutrient ions, carboxylate retention by the tissues of perennial ryegrass was ...
Dijkshoorn, W., Lathwell, D.J., Wit, C.T., de   +2 more
core   +2 more sources