Results 41 to 50 of about 8,233 (279)

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Reduced glomerular filtration and enhanced bicarbonate reabsorption maintain metabolic alkalosis in humans [PDF]

, 1984
Reduced glomerular filtration and enhanced bicarbonate reabsorption maintain metabolic alkalosis in humans. The mechanism that sustains chloride-depletion metabolic alkalosis is presumed to be a stimulation of renal acidification, so that the elevated ...
Berger, Bruce E., Sebastian, Anthony, Cogan, Martin G.   +2 more
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Ménage-à-trois: The ratio of bicarbonate to CO2 and the pH regulate the capacity of neutrophils to form NETs

Frontiers in Immunology, 2016
In this study we identified and characterized the potential of a high ratio of bicarbonate to CO2 and a moderately alkaline pH to render neutrophils prone to undergo neutrophil extracellular trap (NET) formation.
Christian Maueröder, Aparna Siddharth Mahajan, Susanne Paulus, Stefanie Nowecki, Jonas Hahn, Deborah Kienhöfer, Mona Helena Biermann, Philipp Tripal, Ralf Philipp Friedrich, Luis Enrique Munoz, Markus F Neurath, Christoph Becker, Georg Andreas Schett, Martin Herrmann, Moritz Leppkes   +14 more
doaj   +1 more source

On the Decomposition of Bicarbonate. IV

Nippon kagaku zassi, 1953
Ryokichi Tsuchiya
openaire   +4 more sources

Chemisorption of CO2 on diaminated silica as bicarbonates and different types of carbamate ammonium ion pairs

, 2020
The chemisorption of CO2 on aminated silica has a rich chemistry, and its details are important to research in relation to CO2 capture and catalytic chemistry.
Hedin, Niklas, Jaworski, Aleksander,, Szego, Anthony E.,, Szego, Anthony E., Jaworski, Aleksander, Hedin, Niklas,   +5 more
core   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

MP30: Impact des bicarbonates sur le devenir des patients souffrant dun arrêt cardiaque préhospitalier

, 2018
Introduction: Les patients souffrant dun arrêt cardiaque extra hospitalier (ACEH) sont fréquemment traités à laide de soins avancés en réanimation cardiovasculaire (SARC).
J. Chauny, A. Denault, Y. Lamarche, F. Bernard, M. Iseppon, A. Vadeboncoeur, C. Sokoloff, M. Albert, J. Morris, R. Daoust, J. Paquet, F. de Champlain, A. Cournoyer, E. Piette, S. Cossette, L. Londei-Leduc, E. Notebaert, D. Larose   +17 more
core   +1 more source

Adaptive Foam 3D Printing of Ultralight and Multifunctional Materials

Advanced Engineering Materials, EarlyView.
Adaptive foam 3D printing, enabled by expandable microspheres, imparts cellular structures to thermoplastic and thermosetting polymers, manufactured through a variety of processes including fused filament fabrication, direct ink writing, digital light processing, and inkjet printing.
Nariman Rajabifar, Amir Ameli
wiley   +1 more source