Results 81 to 90 of about 6,433 (249)

Tailored D‐π Conjugation Boosts Piezocatalytic CO2 Reduction in a Platinum(II)‐Acetylide Framework

Advanced Science, EarlyView.
The highly conjugated metalII‐acetylide framework demonstrates efficient ultrasound‐driven conversion of CO2 to CO. The piezoelectric field generated by ultrasound facilitates electron transfer from the tetraphenylene π‐column to the MII‐bis(acetylide) moiety, enabling CO2 activation. Compared to PdII‐ and NiII‐based analogues, the stronger d–π orbital
Mude Zhu, Yingtang Zhou, Kai Wang, Xiaoyun Fan, Yang Ding, Wai‐Yeung Wong, Linli Xu   +6 more
wiley   +1 more source

SuFEx‐Enabled Reprogramming of Flavonoids for Selective α‐Glucosidase Covalent Inhibition

Advanced Science, EarlyView.
Selective inhibition of intestinal α‐glucosidase remains limited by poor enzyme specificity and off‐target metabolic effects. Here, SuFEx click chemistry is used to reprogram natural flavonoids into covalent inhibitors with enhanced α‐glucosidase selectivity and controlled reactivity. This strategy enables effective regulation of carbohydrate digestion
Fengyu Guo, Liwei Zhang, Minlong Wang, Yanjin Du, Tianyu Zhang, Hao Chen, Jiazeng Sun, Yang Yu, Zude He, Jie An, Xiaoxu Zhang, Weilin Lin, Fazheng Ren, Pengjie Wang, Ping Liu   +14 more
wiley   +1 more source

Operando Raman Spectroscopy Reveals Backpressure‐Controlled Dynamics in Diluted CO2 Electrolysis

Advanced Science, EarlyView.
High backpressure operation governs the CO2 reduction reaction (eCO2RR) kinetics and selectivity, as well as the CO2 and water dynamics, as revealed through operando Raman spectroelectrochemical measurement. Operating eCO2RR near diffusion‐limited conditions provides a platform for investigating the competition between eCO2RR and the hydrogen evolution
Muhammad Adib Abdillah Mahbub, Bashir Eid, Kinran Lau, Nini Zhang, Thomas Quast, Ann Cathrin Brix, Debanjan Das, Wolfgang Schuhmann   +7 more
wiley   +1 more source

Molecular Mobility of N‐Acetylgalactosamine‐Modified Cyclodextrins on a Polyrotaxane for Highly Efficient Liver Targeting of Antibody Chimeras and Genome‐Editing Ribonucleoproteins

Advanced Science, EarlyView.
Monovalent N‐acetylgalactosamine (GalNAc)‐modified polyrotaxane enables efficient liver targeting by utilizing ligand mobility. The sliding and rotating cyclic components i.e., cyclodextrin in the polyrotaxane dynamically cluster GalNAc moieties, thereby mimicking trivalent interactions with asialoglycoprotein receptors.
Toru Taharabaru, Keiichi Motoyama, Yuting Wen, Zhongxing Zhang, Xuehao Tian, Jun Li, Taishi Higashi   +6 more
wiley   +1 more source

Detection of Novichok and V-Group Nerve Agents by Chemosensors Containing Nile Blue Chromophore

Chemosensors
This paper presents the results of experiments aiming for the detection and differentiation of selected nerve agents of the Novichok and V-group using simple strip detectors containing colourimetric indicator, specifically chemosensor Nile Blue A ...
Martin Urban, Tomáš Dropa, Markéta Zelenková, Michal Dymák, Vladimír Pitschmann   +4 more
doaj   +1 more source

All‐Flex Plasma Patch for In Vivo Delivery of Reactive Species

Advanced Science, EarlyView.
A fully flexible plasma patch enables stable, conformal treatment on complex biological surfaces and enhances transdermal delivery of reactive species. This platform achieves significant tumor suppression in vivo and reveals coordinated regulation of calcium signaling, metabolism, and programmed cell death, providing a promising strategy for safe and ...
Luxiang Zhao, Abulaihaiti Tuergong, Hanshu Yang, Shuang Xue, An Yan, Mingzhen Wang, Weilong Song, Wenzhe Si, Ruixue Wang   +8 more
wiley   +1 more source

Assessment of the water of the general estuary project for irrigation purposes through the study of the physical and chemical properties of the water and river deposits in the city of Nasiriyah and their comparison with the global determinants

Wasit Journal for Pure Sciences
The study involved collecting samples from five stations located on the main river mouth to study their physical and chemical characteristics in order to assess their suitability for irrigation compared to international irrigation standards. Temperature,
Ali Hussain
doaj   +1 more source

Confinement‐Driven CO Spillover in CuAg@MSN Tandem Catalysts Boosts C2 Selectivity Toward Electrocatalytic CO2 Reduction

Advanced Science, EarlyView.
The CuAg@MSN catalyst developed in this study promotes C─C coupling by regulating the coverage of *CO intermediates through spatial confinement effects, significantly enhancing the selectivity of CO2 electroreduction for C2 product formation. ABSTRACT Tandem catalysts represent a promising paradigm for synergistic electrochemical CO2 reduction (CO2RR ...
Jiaying Zhang, Junjie Huang, Siying Zhang, Yanjia Cui, Chao Kong, Zijian Peng, Huihui Jiang, Sirui Deng, Zhuoyao Chen, Caili Yang, Ketong He, Zhen Li, Yibing Song, Gongwei Wang, Lin Zhuang   +14 more
wiley   +1 more source

Etiology and pathogenesis of duodenal mucosa lesion in chronic pancreatitis

Терапевтический архив, 2009
Aim. To measure content of neuromediators (acetylcholine - Ach, serotonin - 5-NT) and gastrointestinal hormones (cholecystokinine - CCK and secretin) in the blood serum of patients with chronic pancreatitis (CP); to study protective properties of the ...
Lyudmila Vasil'evna Vinokupova, V N Dpozdov, E V Tkachenko, I E Tpubitsyna, G G Vapvanina, L V Vinokurova, V N Drozdov, E V Tkachenko, I E Trubitsyna, G G Varvanina   +9 more
doaj  

p300 Degradation by the p53‐SIAH1 Axis Relieves TBK1 Acetylation to Enhance Innate Antiviral Immunity

Advanced Science, EarlyView.
This study identifies p300 as the acetyltransferase that acetylates TBK1 and inhibits its phosphorylation. Activation of the p53‐SIAH1 axis by immune response downregulates p300 expression to sustain innate antiviral immunity. Conditional p300 knockout in alveolar epithelial cells in vivo promotes antiviral responses and suppresses virus replication ...
Huidi Yu, Zhihao Zhan, Xiaoxiang Pan, Xinyue Zhang, Penggang Liu, Jing Sun, Xiulong Xu   +6 more
wiley   +1 more source