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Clinical implications of the biomechanics of bicuspid aortic valve and bicuspid aortopathy
Frontiers in Cardiovascular Medicine, 2022 Bicuspid aortic valve (BAV), which affects up to 2% of the general population, results from the abnormal fusion of the cusps of the aortic valve. Patients with BAV are at a higher risk for developing aortic dilatation, a condition known as bicuspid ...Ali Fatehi Hassanabad, Melissa A. King, Elena Di Martino, Elena Di Martino, Elena Di Martino, Paul W. M. Fedak, Julio Garcia, Julio Garcia, Julio Garcia, Julio Garcia +9 moredoaj +4 more sourcesA technique for bicuspidization of the aortic valve [PDF]
The Journal of Thoracic and Cardiovascular Surgery, 1959 Although there are a dozen or more etiologies for aortic insufficiency, the ultimate problem is similar in most cases. There is a disparity between the area of the aortic orifice and the area of valve leaflet with which this orifice must be covered during diastole.CRUZAT, EP, LEWIS, FJ, STARZL, TE, WALKER, FB +3 morecore +4 more sourcesInternational consensus statement on nomenclature and classification of the congenital bicuspid aortic valve and its aortopathy, for clinical, surgical, interventional and research purposes.
European Journal of Cardio-Thoracic Surgery, 2021 This International Consensus Classification and Nomenclature for the congenital bicuspid aortic valve condition recognizes 3 types of bicuspid valves: 1.H. Michelena, A. Della Corte, A. Evangelista, J. Maleszewski, W. Edwards, M. Roman, R. Devereux, B. Fernández, F. Asch, A. Barker, L. Sierra-Galan, L. de Kerchove, Susan M. Fernandes, P. Fedak, E. Girdauskas, V. Delgado, S. Abbara, E. Lansac, Siddharth K. Prakash, M. Bissell, B. Popescu, M. Hope, M. Sitges, V. Thourani, P. Pibarot, K. Chandrasekaran, P. Lancellotti, M. Borger, John K. Forrest, J. Webb, D. Milewicz, R. Makkar, M. Leon, S. Sanders, M. Markl, V. Ferrari, W. Roberts, Jae-Kwan Song, P. Blanke, C. White, S. Siu, L. Svensson, A. Braverman, J. Bavaria, T. Sundt, G. El Khoury, R. de Paulis, M. Enriquez-Sarano, Jeroen J. Bax, C. Otto, H. Schäfers +50 moresemanticscholar +2 more sourcesBicuspid aortic valve [PDF]
Annals of Cardiothoracic Surgery, 2017 Bicuspid aortic valve (BAV) has a prevalence of 0.5–1.39% in the general population. The prevalence of BAV in aortic dissection is 3.5–11.8%. Unfortunately, the incidence of aortic dissection in BAV remains unknown. The etiology of BAV is polygenetic, where environmental factors and unknown genetic factors seem to interact to cause BAV.Beth Croce, Christopher Harris, Stine Munkholm-Larsen +2 moreopenaire +5 more sourcesPrevalence of Bicuspid Aortic Valve and Associated Aortopathy in Newborns in Copenhagen, Denmark.
Journal of the American Medical Association (JAMA), 2021 Importance
The prevalence and characteristics of bicuspid aortic valve (BAV) are mainly reported from selected cohorts. BAV is associated with aortopathy, but it is unclear if it represents a fetal developmental defect or is secondary to abnormal valve ...A. Sillesen, Ottilia Vøgg, C. Pihl, A. Raja, K. Sundberg, C. Vedel, H. Zingenberg, F. Jørgensen, N. Vejlstrup, K. Iversen, H. Bundgaard +10 moresemanticscholar +1 more sourceThree-year outcomes of transcatheter aortic valve implantation for bicuspid versus tricuspid aortic stenosis.
EuroIntervention, 2022 BACKGROUND
Transcatheter aortic valve implantation (TAVI) might be a feasible treatment option for more patients with bicuspid aortic valve (BAV) stenosis. However, long-term follow-up data in this population are scarce.Dao Zhou, Abuduwufuer Yidilisi, Jiaqi Fan, Ye Zhang, H. Dai, Gangjie Zhu, Yuchao Guo, Yuxin He, Qifeng Zhu, Xinping Lin, Huajun Li, Jubo Jiang, Stella Ng, Cheng Li, K. Ren, Lihan Wang, Xianbao Liu, Jian’an Wang +17 moresemanticscholar +1 more sourceElucidation of the genetic causes of bicuspid aortic valve disease
Cardiovascular Research, 2022 Aims The present study aims to characterize the genetic risk architecture of bicuspid aortic valve (BAV) disease, the most common congenital heart defect.J. Gehlen, A. Stundl, R. Debiec, F. Fontana, M. Krane, D. Sharipova, C. Nelson, B. Al-Kassou, Ann-Sophie Giel, J. Sinning, C. Bruenger, Carolin Zelck, Laura L Koebbe, P. Braund, T. Webb, S. Hetherington, S. Ensminger, B. Fujita, S. A. Mohamed, M. Shrestha, H. Krueger, M. Siepe, F. Kari, P. Nordbeck, L. Buravezky, M. Kelm, Verena Veulemans, Matti Adam, S. Baldus, K. Laugwitz, Y. Haas, M. Karck, U. Mehlhorn, L. Conzelmann, I. Breitenbach, C. Lebherz, P. Urbanski, Won-Keun Kim, J. Kandels, D. Ellinghaus, U. Nowak-Goettl, P. Hoffmann, F. Wirth, S. Doppler, H. Lahm, M. Dreßen, M. von Scheidt, K. Knoll, T. Kessler, C. Hengstenberg, H. Schunkert, G. Nickenig, M. Nöthen, A. Bolger, S. Abdelilah‐Seyfried, N. Samani, J. Erdmann, T. Trenkwalder, J. Schumacher +58 moresemanticscholar +1 more sourceSafety and Efficacy of Myval Implantation in Patients with Severe Bicuspid Aortic Valve Stenosis—A Multicenter Real-World Experience
Journal of Clinical Medicine, 2022 Bicuspid aortic valve (BAV) is the most common valvular congenital anomaly and is apparent in nearly 50% of candidates for AV replacement. While transcatheter aortic valve implantation (TAVI) is a recommended treatment for patients with symptomatic ...Ahmad El-Koumy, J. Jose, C. Terkelsen, H. Nissen, S. Gunasekaran, M. Abdelshafy, A. Seth, H. Elzomor, Sreenivasa Kumar, F. Bedogni, A. Ielasi, S. Dora, S. Chandra, K. Parikh, D. Unić, W. Wijns, A. Baumbach, D. Mylotte, P. Serruys, O. Soliman +19 moresemanticscholar +1 more sourceA Human Hereditary Cardiomyopathy Shares a Genetic Substrate With Bicuspid Aortic Valve
Circulation, 2022 Background: The complex genetics underlying human cardiac disease is evidenced by its heterogenous manifestation, multigenic basis, and sporadic occurrence. These features have hampered disease modeling and mechanistic understanding. Here, we show that 2 M. Siguero-Álvarez, Alejandro Salguero-Jiménez, Joaquím Grego-Bessa, Jorge de la Barrera, D. MacGrogan, Belén Prados, Fernando Sánchez-Sáez, Rebeca Piñeiro-Sabarís, Natalia Felipe-Medina, C. Torroja, M. Gómez, M. Sabater-Molina, R. Escribá, Ivonne Richaud-Patin, O. Iglesias-García, Mauro Sbroggio, S. Callejas, D. O’Regan, K. McGurk, A. Dopazo, G. Giovinazzo, B. Ibáñez, L. Monserrat, J. Pérez-Pomares, F. Sánchez-Cabo, A. Pendás, Á. Raya, J. Gimeno-Blanes, J. L. de la Pompa +28 moresemanticscholar +1 more source