Results 91 to 100 of about 134,978 (240)

Novel loss of function mutation in NOTCH1 in a family with bicuspid aortic valve, ventricular septal defect, thoracic aortic aneurysm, and aortic valve stenosis [PDF]

, 2020
Radosław Dębiec, Stephen E. Hamby, Peter D. Jones, Sue Coolman, Manish Asiani, Shireen Kharodia, G. Skinner, Nilesh J. Samani, Tom R. Webb, Aidan P. Bolger   +9 more
openalex   +1 more source

Fetal Proximal and Distal Transverse Aortic Arch and Aortic Isthmus Measurements Between 19 and 34 Weeks of Gestation

Journal of Ultrasound in Medicine, Volume 45, Issue 1, Page 43-50, January 2026.
Objectives To assess fetal proximal and distal transverse aortic arch and aortic isthmus (AI) diameters between 19 and 34 weeks of gestation. Methods A prospective cross‐sectional descriptive study was performed in 466 low‐risk pregnancies between 19 and 34 weeks of gestation. Proximal transverse aortic arch (PTAA), distal transverse aortic arch (DTAA),
Hakan Erenel, Kubra Kurt Bilirer, Firat Ersan, Verda Alpay, Isa Ozyilmaz   +4 more
wiley   +1 more source

The role of stress concentration in calcified bicuspid aortic valve

Journal of the Royal Society Interface, 2020
Calcific aortic valve disease (CAVD) is the most common valvular heart disease in the aging population, and is now believed to be a slow, progressive, yet actively regulated process.
T. Qin, A. Caballero, W. Mao, B. Barrett, N. Kamioka, S. Lerakis, Wei Sun   +6 more
semanticscholar   +1 more source

Genotype–Phenotype Correlations in Klinefelter and Turner Syndrome: A Decade of Sex Chromosome Aneuploidy Data From a Single Academic Medical Center

Molecular Genetics &Genomic Medicine, Volume 14, Issue 1, January 2026.
To understand the relationship between genotype and phenotype in sex chromosome aneuploidies, retrospective cytogenetic and clinical data was collected for Klinefelter Syndrome (n = 57) and Turner Syndrome (n = 92) cases from a single academic medical center from 2013 to 2022. The cohorts were divided into subcategories based on the genotype.
Stephanie A. Hart, Joel A. Morales‐Rosado, Xinxiu Xu, Ashwini K. Yenamandra   +3 more
wiley   +1 more source

In vitro characterization of hemodynamics in bicuspid aortic valves: The impact of valve and ascending aortic morphologies

Magnetic Resonance in Medicine, Volume 95, Issue 1, Page 411-429, January 2026.
Abstract Purpose This study investigated the effect of bicuspid aortic valve (BAV) morphology and ascending aortic curvature (AAAc) bending angles on aortic hemodynamics, focusing on transvalvular jets and secondary helical flows that contribute to systolic hemodynamic stress linked to aortic complications.
Kaoru Hattori, Natsuki Nakama, Jumpei Takada, Michinobu Nagao, Yasuhiro Goto, Hiroshi Niinami, Kiyotaka Iwasaki   +6 more
wiley   +1 more source

Bicuspid Aortic Valve: An Update in Morphology, Genetics, Biomarker, Complications, Imaging Diagnosis and Treatment

Frontiers in Physiology, 2019
The bicuspid aortic valve, a kind of heart disease that comes from parents, has been paid attention around the world. Although most bicuspid aortic valve (BAV) patients will suffer from some complications including aortic stenosis, aortic regurgitation ...
Tianshu Liu, M. Xie, Q. Lv, Yuman Li, L. Fang, Li Zhang, Wenhui Deng, Jing Wang   +7 more
semanticscholar   +1 more source

Obstetric outcome in women with congenital heart disease: A nationwide cohort in Sweden

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 1, Page 7-17, January 2026.
In this large national case–control study in women with congenital heart disease, we showed an increased likelihood of giving birth prematurely, by cesarean section, and having a small‐for‐gestational‐age neonate compared to matched controls. Abstract Introduction Survival and healthcare for patients with congenital heart disease have improved, and the
Frida Wedlund, Ellen Widing, Emma von Wowern, Christina Christensson, Sandra Lindstedt, Peder Sörensson, Aleksandra Trzebiatowska‐Krzynska, Zacharias Mandalenakis, Annika Bay, Bengt Johansson, Joanna Hlebowicz   +10 more
wiley   +1 more source

Aortic flow patterns and wall shear stress maps by 4D-flow cardiovascular magnetic resonance in the assessment of aortic dilatation in bicuspid aortic valve disease

Journal of Cardiovascular Magnetic Resonance, 2018
BackgroundIn patients with bicuspid valve (BAV), ascending aorta (AAo) dilatation may be caused by altered flow patterns and wall shear stress (WSS). These differences may explain different aortic dilatation morphotypes.
J. Rodríguez-Palomares, L. Dux-Santoy, A. Guala, R. Kale, G. Maldonado, G. Teixidó-Turà, L. Galián, M. Huguet, F. Valente, L. Gutiérrez, T. González‐Alujas, Kevin M. Johnson, O. Wieben, D. Garcia-Dorado, A. Evangelista   +14 more
semanticscholar   +1 more source

Long-term outcome of bicuspid aortic valve repair using figure-of-8 hitch-up stitchesCentral MessagePerspective

JTCVS Techniques
Objective: To maximize successful repair of bicuspid aortic valves by adding figure-of-8 hitch-up stitches at commissures. Methods: From 2000 to 2022, bicuspid aortic valve repair was performed on 1112 patients at Cleveland Clinic, with 367 patients ...
Fei Xiang, MD, Lin Chen, BA, Raphaelle Chemtob, MD, Eric E. Roselli, MD, Shinya Unai, MD, Patrick Vargo, MD, Marijan Koprivanac, MD, A. Marc Gillinov, MD, Eugene H. Blackstone, MD, Jeevanantham Rajeswaran, PhD, Austin Firth, MS, Milind Y. Desai, MD, MBA, Brian Griffin, MD, Vidyasagar Kalahasti, MD, Lars G. Svensson, MD, PhD   +14 more
doaj   +1 more source

Integrated biomarker landscape for the early detection and management of calcific aortic valve disease

European Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.
Calcific aortic valve disease (CAVD), the leading valvular disorder in older adults, progresses from sclerosis to severe stenosis without effective medical therapies, making early non‐invasive detection essential. Circulating and mechanistic biomarkers reflect core pathogenic axes, including lipid oxidation, inflammation, mineral metabolism ...
Alberto Cook‐Calvete, Silvia Moreta, Maria Delgado‐Marin, Blanca Fernandez‐Rodriguez, Carlos Zaragoza, Marta Saura   +5 more
wiley   +1 more source