Results 141 to 150 of about 56,899 (289)

Yield of Whole Genome Sequencing for Pathogenic Single Nucleotide Variants in Congenital Heart Disease: A Systematic Review and Meta‐Analysis

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective This systematic review and meta‐analysis aimed to assess the diagnostic yield of pathogenic or likely pathogenic (P/LP) single nucleotide variants (SNVs) using whole genome sequencing (WGS) in congenital heart disease (CHD). Methods A systematic search of three databases (2000–2024) was conducted, and two reviewers independently ...
Hiba J. Mustafa, Parisa Najjariasl, Faezeh Aghajani, Enaja V. Sambatur, Andrew Rodenbarger, Stephanie Guseh, Amy E. Roberts, Alireza A. Shamshirsaz   +7 more
wiley   +1 more source

Type F congenital quadricuspid aortic valve: A very rare case diagnosed by 3-dimenional transoesophageal echocardiography [PDF]

, 2014
Congenital quadricuspid aortic valve (QAV) is a rare cardiac anomaly. Several different anatomical variations of a quadricuspid aortic valve have been described.
Cooke JC, Davia JE, Di Pino A, Feldman BJ, Fernández B, Gulyasy B, Hazlyna Kamaruddin, Holt NF, Hurwitz LE, Olson LJ, Pankaj Garg, Rachel Orme, Scrofani R, Takeda N, Tang YF, Tutarel O, Victoria Watt, Ward C   +17 more
core   +2 more sources

Heartbeat: phenotypic heterogeneity of bicuspid aortic valve disease [PDF]

Heart, 2018
Bicuspid aortic valve (BAV) disease is common, affecting 1%–2% of the entire population, with nearly all BAV patients eventually requiring aortic valve replacement, often with concurrent aortic surgery for dilation of the sinuses or ascending aorta. Although echocardiography allows easy diagnosis of the presence of BAV disease early in life, we are ...
openaire   +2 more sources

Chronic Otitis Media Resulting in Aortic Valve Replacement: A Case Report

Journal of Tehran University Heart Center, 2015
The bicuspid aortic valve is known to be the most common congenital cardiac malformation, with an approximate incidence rate of 1-2% in the general population. Most patients are unaware of the disease until the onset of infective endocarditis, which is a
Adem Guler, Mehmet Ali-Sahin, Fahri Gurkan-Yesil, Uzeyir Yildizoglu, Sait Demirkol, Mehmet Arslan   +5 more
doaj  

Assessment of hemodynamic conditions in the aorta following root replacement with composite valve-conduit graft [PDF]

, 2015
This paper presents the analysis of detailed hemodynamics in the aortas of four patients following replacement with a composite bio-prosthetic valve-conduit.
Athanasiou, T, Cheng, Z, Jarral, OA, Kidher, E, O'Regan, DP, Wood, NB, Xu, XY   +6 more
core   +1 more source

Aged Zebrafish as a Spontaneous Model of Cardiac Valvular Disease

Aging Cell, EarlyView.
Natural ageing in zebrafish results in spontaneous development of valvular degeneration in both the atrioventricular (AV) and bulboventricular (BV) valves. Aged zebrafish valves are larger and exhibit cystic regions, immune cell infiltration, early osteoblast differentiation and increased regurgitation.
Laura Bevan, Jessica Radford, Helena Urquijo, Joseph Carr, Alice Etheridge, Stephen Cross, Melanie Hezzell, Rebecca J. Richardson   +7 more
wiley   +1 more source

Transcatheter aortic valve replacement in Bicuspid Aortic Valve Disease: An Insight

Journal of Medical Research and Innovation, 2019
As per the current scenario, role of Transcatheter aortic valve replacement (TAVI) is controversial in bicuspid aortic valve stenosis. All the randomized clinical trials comparing outcomes of TAVI with surgery till date, have excluded patients with bicuspid aortic valve.
Varun Kumar, Arvin Narula, Varshil Mehta, Mauricio G. Cohen, Nileshkumar J. Patel, Nikhil Nalluri, Varunsiri Atti   +6 more
openaire   +3 more sources

Cardiovascular Health in Women—Across the Lifespan

Clinical Endocrinology, EarlyView.
ABSTRACT Cardiovascular disease (CVD) remains the leading cause of mortality and morbidity among women worldwide. However, CVD continues to be perceived as a predominantly male issue. CVD in women therefore remains understudied, underrecognized and undertreated.
Jaya Chandrasekhar, Jessica Yao, Simone Gong, Madhuka Wijayarathne, Monique Watts, Swati Mukherjee   +5 more
wiley   +1 more source

An Infective Endocarditis Case Report Involving Both Native Aortic and Mitral Valves Due to Streptococcus Vestibularis

Prague Medical Report
Infective endocarditis (IE) is a life-threatening disease, with its mortality rate varying depending on the infectious agent. Streptococci are among the most common causes of infective endocarditis.
Hüseyin Döngelli, Baver Kızartıcı, Mustafa Oktay Tarhan, Ebru Özpelit, Osman Nejat Sarıosmanoğlu, Hatice Kübra Taşçı   +5 more
doaj   +1 more source

Preliminary Biomarkers for Identification of Human Ascending Thoracic Aortic Aneurysm [PDF]

, 2014
Background: Human ascending thoracic aortic aneurysms (ATAAs) are life threatening and constitute a leading cause of mortality in the United States.
Bhasin, Manoj K., Black, Kendra M., Dillon, Simon T., Hagberg, Robert C., Khabbaz, Kamal R., Levitsky, Sidney, Libermann, Towia A., Masuzawa, Akihiro, McCully, James D., Rettagliati, Verna M., Toumpoulis, Ioannis K., Trovato, Mary E.   +11 more
core   +1 more source