Results 151 to 160 of about 56,899 (289)

Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development

Journal of Anatomy, Volume 246, Issue 4, Page 616-630, April 2025.
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah, Anna Wilsdon, Aseel Abbad, Sophie Rochette, Frances Bu'Lock, Asma Ali Saed, Marc‐Phillip Hitz, J. David Brook, Siobhan Loughna   +8 more
wiley   +1 more source

Surgical aortic valve replacement etiologies, hemodynamics, and outcomes in 1346 patients from the Malaysian heart centre

Journal of Cardiothoracic Surgery
Background This study examined the characteristics and outcomes of surgical aortic valve replacement (SAVR) both isolated and in combination with other cardiac surgery in Malaysia from 2015 to 2021. Methods This was a retrospective study of 1346 patients
Aslannif Roslan, Chong Kee Soon, Tey Yee Sin, Ahmad Tantawi Jauhari Aktifanus, Soh Si Ling, Wong Kian Boon, Beni I. Rusani, Hafidz Abd Hadi, Jayakhanthan Kolanthaivelu, Shaiful Azmi Yahaya, Jeswant Dillon, Alwi M. Yunus   +11 more
doaj   +1 more source

The Duke minor criterion "predisposing heart condition" in native valve infective endocarditis – a systematic review

Swiss Medical Weekly, 2018
BACKGROUND The term “predisposition” is used as an indication of antimicrobial prophylaxis to prevent infective endocarditis and as a criterion for diagnosing infective endocarditis according to the modified Duke criteria.
Annina E. Buechi, Mario Hoffmann, Stephan Zbinden, Andrew Atkinson, Parham Sendi   +4 more
doaj   +1 more source

The Evolving Landscape of CHD Genetics: A Contemporary Guide to Genetic Testing and Management

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Congenital heart disease (CHD) is the most common birth defect, affecting an estimated 9.4/1000 infants globally. The genetics of CHD is complex, with most cases thought to have multifactorial aetiology, implicating both genetic and environmental factors.
Bridget R. O'Malley, Gary F. Sholler, Janine Smith, Gillian M. Blue   +3 more
wiley   +1 more source

The influence of bicuspid aortic valves on the dynamic pressure distribution in the ascending aorta: a porcine ex vivo model † [PDF]

, 2017
OBJECTIVES The aim of the study was to simulate the effect of different bicuspid aortic valve configurations on the dynamic pressure distribution in the ascending aorta. METHODS Aortic specimens were harvested from adult domestic pigs.
Aigner, Philipp, Czerny, Martin, Dziodzio, Tomasz, Fechtig, Daniel, Gschlad, Verena, Juraszek, Andrzej, Schima, Heinrich, Stoiber, Martin   +7 more
core  

Development and Morphology of the Ventricular Outflow Tracts. [PDF]

, 2016
It is customary, at the current time, to consider many, if not most, of the lesions involving the ventricular outflow tract in terms of conotruncal malformations.
Anderson, RH, Brown, NA, Mohun, TJ, Mori, S, Spicer, DE   +4 more
core   +2 more sources

Aortic and cardiovascular remodelling after thoracic endovascular aortic repair for blunt traumatic aortic injury in younger patients: A narrative review of physiological and clinical outcomes

Experimental Physiology, EarlyView.
Abstract Blunt traumatic aortic injury (BTAI) is severe, often fatal in younger populations due to high‐energy deceleration mechanisms. Thoracic endovascular aortic repair (TEVAR) has revolutionised BTAI treatment, surpassing the previously standard open surgical repair in mortality and complication rates.
Marco David Bokobza De la Rosa, Matti Jubouri, Thurkga Moothathamby, Mohamed Refaie, Ali Murtada, Idhrees Mohammed, Ian M. Williams, Damian M. Bailey, Mohamad Bashir   +8 more
wiley   +1 more source

Bicuspid and Unicuspid Aortic Valve: Fate of Moderate/Severe Mixed Aortic Valve Disease

Congenital Heart Disease, 2016
There is a paucity of data about mixed aortic valve disease (MAVD) in patients with bicuspid/unicuspid aortic valve (BAV). This study sought to describe the outcomes of patients with moderate/severe MAVD.We queried our database for patients with BAV and moderate/severe MAVD seen between 1994 and 2013.
Alexander C. Egbe, Heidi M. Connolly, Carole A. Warnes, Joseph T. Poterucha   +3 more
openaire   +3 more sources

Histologic abnormalities of the ascending aorta and pulmonary trunk in patients with bicuspid aortic valve disease: Clinical relevance to the ross procedure [PDF]

, 1999
Mauro P.L de, Yaron Moshkovitz, Jagdish Butany, Tirone E. David   +3 more
openalex   +1 more source

Never say never

Journal of Hospital Medicine, EarlyView.
Gurpreet Dhaliwal, Jagmeet Dhingra, Tom Fraser, Leal Herlitz, James Pile   +4 more
wiley   +1 more source