Results 91 to 100 of about 32,621 (266)

Gut microbiota‐derived butyric acid regulates calcific aortic valve disease pathogenesis by modulating GAPDH lactylation and butyrylation

iMeta, EarlyView.
Multi‐omics sequencing and correlation analysis identified the beneficial role of Faecalibacterium prausnitzii (F. prausnitzii)‐derived butyric acid (BA) as a key metabolite in the restoration of valve function in calcific aortic valve disease (CAVD). The therapeutic efficacy of BA in attenuating CAVD progression was confirmed in vitro, ex vivo, and in
Chunli Wang, Zongtao Liu, Tingwen Zhou, Jiaqin Wu, Fan Feng, Shunshun Wang, Qingjia Chi, Yongqiang Sha, Shuai Zha, Songren Shu, Linghang Qu, Qianqian Du, Huiming Yu, Li Yang, Anna Malashicheva, Nianguo Dong, Fei Xie, Guixue Wang, Kang Xu   +18 more
wiley   +1 more source

P4.03 APOPTOSIS IN THE MEDIA OF THE AORTIC WALL AND ITS RELATIONSHIP WITH AORTIC VALVE MORPHOLOGY IN AORTIC DILATATION

Artery Research, 2013
Background: The aortic valve is normally tricuspid but may vary in that it can be made up of 1, 2 or 4 leaflets with each of these often associated with aortopathy, most commonly aortic dilatation.
H. Edwards, J. Dargan, L. Elliot, A. Modi, S. Ohri, P. Townsend   +5 more
doaj   +1 more source

Percutaneous Bicuspidization of the Tricuspid Valve

JACC: Cardiovascular Imaging, 2017
A 75-year-old woman who was known to have had previous aortic and mitral valve replacement with mechanical prostheses, permanent atrial fibrillation, type 2 diabetes mellitus, and hypothyroidism presented with right-sided heart decompensation (severe edema of the lower extremities ...
Latib, Azeem, Ancona, Marco B., Agricola, Eustachio, Giannini, Francesco, Mangieri, Antonio, Regazzoli, Damiano, Monaco, Fabrizio, ALFIERI, OTTAVIO, Hahn, Rebecca, COLOMBO, ANTONIO   +9 more
openaire   +3 more sources

Embryonic development of bicuspid aortic valves

Progress in Cardiovascular Diseases, 2020
Bicuspid aortic valve (BAV) is the most common congenital cardiac malformation, frequently associated with aortopathies and valvulopathies. The congenital origin of BAV is suspected to impact the development of the disease in the adult life. During the last decade, a number of studies dealing with the embryonic development of congenital heart disease ...
Soto-Navarrete, María Teresa, López-Unzu, Miguel A., Durán-Boyero, Ana Carmen, Fernández-Corujo, Borja   +3 more
openaire   +5 more sources

Valve-preserving root replacement in bicuspid aortic valves [PDF]

The Journal of Thoracic and Cardiovascular Surgery, 2010
Bicuspid aortic valve anatomy is associated with aortic root aneurysm in a relevant proportion of patients. These patients require root replacement for prognostic reasons, and the valve may be preserved. The objective of this analysis is to analyze the early and late outcomes of root remodeling for bicuspid aortic valve.Between November 1995 and ...
Diana Aicher, Takashi Kunihara, Brigitte Brittner, Hans-Joachim Schäfers, Peter Fries   +4 more
openaire   +2 more sources

The myocardial and coronary histopathology and pathogenesis of hypoplastic left heart syndrome [PDF]

, 2015
Hypoplastic left heart syndrome has the greatest mortality rate among all CHDs and without palliation is uniformly fatal. Despite noble efforts, the aetiology of this syndrome is unknown and a cure remains elusive.
Cole, Charles R, Eghtesady, Pirooz
core   +2 more sources

Dexmedetomidine as a Ropivacaine Adjuvant in a Thoracic Paravertebral Block Combined With an Erector Spinae Plane Block for Improving Early Quality of Recovery After Transapical Transcatheter Aortic Valve Implantation

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The study aimed to investigate the effectiveness of dexmedetomidine (Dex) as an adjuvant for ropivacaine in a thoracic paravertebral block (TPVB) combined with an erector spinae plane block (ESPB) for improving early quality of recovery and postoperative pain after transapical transcatheter aortic valve implantation (TAVI).
Gui‐Ling Dong, Rong‐En Qiu, Chen‐Zhan Xu   +2 more
wiley   +1 more source

TAVI with the ACURATE neo transcatheter heart valve in special populations: A systematic review

Hellenic Journal of Cardiology, 2022
The ACURATE neo transcatheter aortic valve is a self-expanding device suitable for both transfemoral and transapical approach, but specific groups of patients are under-represented in clinical trials.
Leonidas Koliastasis, Ioannis Doundoulakis, Damianos G. Kokkinidis, Anastasios Milkas, Maria Drakopoulou, George Benetos, Georgios Latsios, Andreas Synetos, Konstantina Aggeli, Dimitrios Tousoulis, Konstantinos Tsioufis, Konstantinos Toutouzas   +11 more
doaj  

Bronchopulmonary arteriovenous malformation presenting as cryptogenic hemoptysis in a patient with bicuspid aortic valve

Lung India, 2020
We report the case of a 44-year-old male patient with bicuspid aortic valve, presenting with hemoptysis. Catheter angiography revealed an abnormal communication between bronchial and pulmonary artery, which remained undetected on computed tomography ...
Ujjwal Gorsi, Madhurima Sharma, Tejeshwar Singh Jugpal, Ashish Bhalla, Manavjit Singh Sandhu   +4 more
doaj   +1 more source

BICUSPID AORTIC VALVE: GENDER DIFFERENCE IN PREVALENCE, VALVE MORPHOLOGY AND BICUSPID AORTOPATHY

Journal of the American College of Cardiology, 2016
Bicuspid aortic valve (BAV) is the most common congenital heart disease. The aim of this study is to define the gender differences in prevalence, valve morphology and dysfunction (aortic stenosis [AS]/regurgitation [AR]), aortopathy, dissection and endocarditis in a large cohort of BAV patients ...
Kong, W.K.F., Regeer, M., Poh, K.K., Yip, J., Ng, A., McCormack, L., Shanks, M., Kamperidis, V., Marsan, N.A., Delgado, V., Bax, J.   +10 more
openaire   +3 more sources