Results 91 to 100 of about 34,124 (288)

Valve-preserving root replacement in bicuspid aortic valves [PDF]

The Journal of Thoracic and Cardiovascular Surgery, 2010
Bicuspid aortic valve anatomy is associated with aortic root aneurysm in a relevant proportion of patients. These patients require root replacement for prognostic reasons, and the valve may be preserved. The objective of this analysis is to analyze the early and late outcomes of root remodeling for bicuspid aortic valve.Between November 1995 and ...
Schäfers, Hans-Joachim, Kunihara, Takashi, Fries, Peter, Brittner, Brigitte, Aicher, Diana   +4 more
openaire   +2 more sources

Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development

Journal of Anatomy, Volume 246, Issue 4, Page 616-630, April 2025.
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah, Anna Wilsdon, Aseel Abbad, Sophie Rochette, Frances Bu'Lock, Asma Ali Saed, Marc‐Phillip Hitz, J. David Brook, Siobhan Loughna   +8 more
wiley   +1 more source

P4.03 APOPTOSIS IN THE MEDIA OF THE AORTIC WALL AND ITS RELATIONSHIP WITH AORTIC VALVE MORPHOLOGY IN AORTIC DILATATION

Artery Research, 2013
Background: The aortic valve is normally tricuspid but may vary in that it can be made up of 1, 2 or 4 leaflets with each of these often associated with aortopathy, most commonly aortic dilatation.
H. Edwards, J. Dargan, L. Elliot, A. Modi, S. Ohri, P. Townsend   +5 more
doaj   +1 more source

The influence of the aortic valve angle on the hemodynamic features of the thoracic aorta [PDF]

, 2019
Since the first observation of a helical flow pattern in aortic blood flow, the existence of helical blood flow has been found to be associated with various pathological conditions such as bicuspid aortic valve, aortic stenosis, and aortic dilatation ...
Ha, H, Kim, G.B, Kim, N, Kim, Y.-H, Kweon, J, Lee, S.J, Yang, D.H.   +6 more
core   +1 more source

The Evolving Landscape of CHD Genetics: A Contemporary Guide to Genetic Testing and Management

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Congenital heart disease (CHD) is the most common birth defect, affecting an estimated 9.4/1000 infants globally. The genetics of CHD is complex, with most cases thought to have multifactorial aetiology, implicating both genetic and environmental factors.
Bridget R. O'Malley, Gary F. Sholler, Janine Smith, Gillian M. Blue   +3 more
wiley   +1 more source

Recurrent infective endocarditis involving bicuspid aortic valve presenting with a rare complication: The deadly kiss

Journal of the Indian Academy of Echocardiography & Cardiovascular Imaging, 2018
Bicuspid aortic valve, the most common congenital cardiac lesion, is frequently associated with infective endocarditis (IE), and this combination is notoriously associated with increased prevalence of periannular complications.
Arnab Ghosh Chaudhury, Prabhavathi Bhat, C N Manjunath, C M Satvic   +3 more
doaj   +1 more source

Reparación valvular aórtica bicúspide. Resultados

Cirugía Cardiovascular, 2020
Resumen: Introducción y objetivos: Las guías de práctica clínica no mencionan, específicamente, la reparación valvular en pacientes con insuficiencia aórtica y válvula aórtica bicúspide como alternativa al implante protésico. La reparación en bicúspides
Rubén Álvarez-Cabo, Carlota Vigil-Escalera, Alain E. Escalera, Blanca Meana Fernández, María Martín, Carlota Salmerón, Rocío Díaz Méndez, Daniel Hernández-Vaquero, Juan Meca, Pilar Mencía, Martín Zabala Morales, Francisco Callejo Magaz, Juan Carlos Llosa, Carlos Morales Pérez, Jacobo Silva Guisasola   +14 more
doaj   +1 more source

The living aortic valve: From molecules to function. [PDF]

, 2014
The aortic valve lies in a unique hemodynamic environment, one characterized by a range of stresses (shear stress, bending forces, loading forces and strain) that vary in intensity and direction throughout the cardiac cycle.
Bertazzo, S, Butcher, JT, Chester, AH, El-Hamamsy, I, Latif, N, Yacoub, MH   +5 more
core   +1 more source

Novel loss of function mutation in NOTCH1 in a family with bicuspid aortic valve, ventricular septal defect, thoracic aortic aneurysm, and aortic valve stenosis [PDF]

, 2020
Radosław Dębiec, Stephen E. Hamby, Peter D. Jones, Sue Coolman, Manish Asiani, Shireen Kharodia, G. Skinner, Nilesh J. Samani, Tom R. Webb, Aidan P. Bolger   +9 more
openalex   +1 more source

Never say never

Journal of Hospital Medicine, EarlyView.
Gurpreet Dhaliwal, Jagmeet Dhingra, Tom Fraser, Leal Herlitz, James Pile   +4 more
wiley   +1 more source