Results 81 to 90 of about 41,404 (206)

Chemical space guided discovery of antimicrobial bridged bicyclic peptides against Pseudomonas aeruginosa and its biofilms [PDF]

, 2017
Here we used a new strategy for exploring the peptide chemical space to discover bicyclic antimicrobial peptides.
Reymond, Jean-Louis, Probst, Daniel, Gaëlle Michaud, Christian van Delden, Gan, Bee-Ha, Michaud, Gaëlle, Doglia, Silvia Maria, Daniel Probst, Silvia Maria Doglia, Thilo Köhler, Köhler, Thilo, Antonino Natalello, Di Bonaventura, Ivan, Javor, Sacha, Natalello, Antonino, Ricardo Visini, Achim Stocker, Darbre, Tamis, Visini, Ricardo, van Delden, Christian, Jin, Xian, Sacha Javor, Stocker, Achim, Xian Jin, Ivan Di Bonaventura, Jean-Louis Reymond, Bee-Ha Gan, Tamis Darbre   +27 more
core   +1 more source

On the nullity of bicyclic graphs

, 2008
The nullity of a graph is the multiplicity of the eigenvalue zero in its spectrum. In this paper, we obtain the nullity set of bicyclic graphs of order n, and determine the bicyclic graphs with maximum ...
Liu, Bolian, Hu, Shengbiao, Xuezhong, Tan   +2 more
core   +1 more source

Synthesis of 2'-O,3'-C-linked bicyclic nucleosides and bicyclic oligonucleotides

, 1997
The 3′-C-allyl furanose 4 has been used as a precursor for synthesis of the novel 2′-O,3′-C-linked bicyclic thymine nucleosides 15, 16, 20 and 25. The three bicyclic β-nucleosides 15, 20 and 25 have been incorporated into oligodeoxynucleotides.
Nielsen, Poul; id_orcid, Olsen, Carl Erik, Wengel, Jesper, Pfundheller, Henrik M.   +3 more
core   +1 more source

A Bicyclic Analog of the Linear Peptide Arodyn Is a Potent and Selective Kappa Opioid Receptor Antagonist

Molecules
Kappa opioid receptor (KOR) antagonists have potential therapeutic applications in the treatment of stress-induced relapse to substance abuse and mood disorders.
Solomon A. Gisemba, Michael J. Ferracane, Thomas F. Murray, Jane V. Aldrich   +3 more
doaj   +1 more source

Condensation-ring Expansion Reaction of Formyl[2.2.1]bicyclic Carbinols with Para-substituted Phenyl Amines: Application to the Preparation of [3.2.1]bicyclic N-aryl-1,2,3-oxathiazolidine-2-oxide Agents

, 2020
[[abstract]]Individual reaction of camphene-derived endo-formyl[2.2.1]bicyclic carbinol and that of camphor-derived exo-formyl[2.2.1]bicyclic carbinol with parent and para-substituted phenyl amines gave regio- and stereospecific corresponding [3.2.1 ...
楊德芳, Yang, TF
core   +2 more sources

Minimum Detour Index of Bicyclic Graphs [PDF]

, 2012
The detour index of a connected graph is defined as the sum of the detour distances (lengths of longest paths) between unordered pairs of vertices of the graph. A graph with n vertices and n + 1 edges is called a bicyclic graph.
Chunjuan Du
core  

An Unexpected Tandem Reaction between N-Butadienyl-N-alkylketene N,O- Trimethylsilylacetals of Propionamide and Activated Dienophiles like N-Phenyl-maleimide or Acryloyl Chloride

CHIMIA, 1993
Starting from the N-butadienyl-N-alkylpropionamides 1a-1c the corresponding N,O-trimethy lsilylacetals could be obtained using the mixture of LDA and trimethylsilyl chloride in THF. The unexpected reaction sequence Diels-Alder reaction/acylation
Marcel Baak, Yves Rubin, Andreas Franz, Helen Stoeckli-Evans, Laurant Bigler, Jiirgen Nachbauer, Reinhard Neier   +6 more
doaj   +2 more sources

Bicyclic Directed Triple Systems

, 1998
A directed triple system of order v, denoted DTS(v), is said to be bicyclic if it admits an automorphism whose disjoint cyclic decomposition consists of two cycles.
Gardner, Robert B.
core  

Bicyclic Units in some Integral Group Rings

, 1995
A description is given of the unit group for the two groups G = D12 and G = D8 × C2. In particular, it is shown that in both cases the bicyclic units generate a torsion-free normal complement.
E. Jespers
core   +1 more source

Phage-encoded bismuth bicycles enable instant access to targeted bioactive peptides

Communications Chemistry
Genetically encoded libraries play a crucial role in discovering structurally rigid, high-affinity macrocyclic peptide ligands for therapeutic applications.
Sven Ullrich, Upamali Somathilake, Minghao Shang, Christoph Nitsche   +3 more
doaj   +1 more source