Results 141 to 150 of about 1,782 (193)

Enhancement of gemcitabine toxicity and specificity through PI3K/Akt/Nrf2 pathway inhibition in pancreatic cancer. [PDF]

Front Pharmacol
Chen YS, O'Hagan S, Day PJR.
europepmc   +1 more source

A network-driven computational framework for identifying FDA-approved drug repurposing across heterogeneous brain cancers. [PDF]

Front Mol Biosci
Prakash O.
europepmc   +1 more source

MT-ConBiFormer-GPT: multi-target molecular generation for low-data drug discovery via a contrastive BiFormer-GPT architecture and curriculum learning with cross-domain generalization. [PDF]

Brief Bioinform
Norouzi R, Abbasi K, Razzaghi P, Gharaghani S.   +3 more
europepmc   +1 more source

Computational-experimental integration identifies potent carbohydrate-hydrolyzing enzyme inhibitors from Nardostachys jatamansi: molecular docking, dynamics and pharmacokinetic predictions. [PDF]

Front Pharmacol
Iqbal MJ, Malik I, Bernal G, Salas-Burgos AM, Salazar LA.   +4 more
europepmc   +1 more source

A helical peptide antagonist of the human growth hormone receptor.

Endocrinology
Nahar K, Basu R, Ahmad A, Pettis JA, Gamage U, Holub JM, Kopchick JJ.   +6 more
europepmc   +1 more source

Network Pharmacology-Serum Metabolomics Integration Identifies Key Targets, Biomarkers and Mechanism of Sendeng-4 in Rheumatoid Arthritis Therapy. [PDF]

Int J Gen Med
Zhou F, Li J, Zhou Y, Zhang X, Luo J, Li X, Sun W, Zhang Q, Li M.   +8 more
europepmc   +1 more source

Crystal structure and Hirshfeld surface analysis of <i>N</i>-(1<i>H</i>-benzo[<i>d</i>]imidazol-2-yl)acetamide. [PDF]

Acta Crystallogr E Crystallogr Commun
Tojiboev AG, Okmanov R, Abdurazakov A, Saidov S, Rakhmatov E, Kodirov A, Elmuradov B.   +6 more
europepmc   +1 more source

Intranasal Delivery of Curcumin-Loaded Pure Drug Self-Assembled Lipid-Based Nanoparticles for Targeted Therapy of Depression. [PDF]

Int J Nanomedicine
Chen T, Liu X, Li D, Cheng Z, Zheng X, Yu Z.   +5 more
europepmc   +1 more source

Integrated <i>in silico</i>-<i>in vitro</i> and pharmacokinetic profiling of <i>Thymus vulgaris</i>-derived metabolites targeting multidrug resistance pathways in extensively drug-resistant <i>Acinetobacter baumannii</i> (muks92). [PDF]

Front Microbiol
Abdulkareem AH, Mukhles Ahmed M, Abed Latef Al-Meani S, Abdulkareem EH.   +3 more
europepmc   +1 more source

Membrane-targeted schiff base derivatives overcome MRSA resistance through phosphatidylglycerol binding and ROS-mediated killing. [PDF]

Front Chem
Liu Y, Hu L, Liu B, Qu Z.
europepmc   +1 more source