Effects of Hazard Types on Hazard Perception and Decision-Making Among Adolescent Bicyclists: Results of a Hazard Prediction Task. [PDF]
Guo J, Xu L, Sun L.
europepmc +1 more source
Hybrid macrocyclic peptides unite genetically encoded peptide libraries with the structural complexity of synthetic small molecules. This Review critically analyzes phage‐compatible cyclization and diversification chemistries, highlights emerging opportunities beyond traditional cysteine‐based approaches, and outlines how future advances may enable the
Titia Rixt Oppewal, Clemens Mayer
wiley +1 more source
Chiral Pyrazolinylidene Complexes for Asymmetric Catalysis
The synthesis and application of pyrazolin‐5‐ylidene NHC chiral‐at‐ruthenium catalysts is reported. The strong donating pyrazolin‐5‐ylidene ligands led to highly electron rich ruthenium complexes, which showed excellent catalytic activity and enantioselectivity in the intramolecular aziridination of an alkene.
Felix Möller +6 more
wiley +1 more source
National Burden of Bicyclist Hospitalizations in the United States by Rurality, 2016-2020. [PDF]
Ghanbari A +5 more
europepmc +1 more source
The Mechanism of Visible‐Light Photochemical Rearrangements of Conjugated Amide Enolates
Visible light irradiation of extended enolates of N‐benzylamides leads to homolytic C─N Bond cleavage, generating a biradical. Computational and mechanistic studies suggest rapid radical recombination within a solvent cage to give either ring‐expanded or rearranged products. ABSTRACT Deprotonation of conjugated amides forms colored solutions of lithium
James Mortimer +3 more
wiley +1 more source
The status and politics of bicycling in the cities of low- and middle-income countries. [PDF]
Kannan SB +7 more
europepmc +1 more source
N‐Sulfonyl Azalevoglucosan: A Versatile Platform for the Synthesis of Polysubstituted Piperidines
Gain by strain: The synthesis of a levoglucosan analog, in which the pyranose oxygen has been replaced by a nitrogen, allows navigation on the piperidine ring to iteratively install functional groups at C1, C2, C3, C4, and C6 positions using simple experimental protocols with minimal protecting group manipulation.
Dylan Yorga +6 more
wiley +1 more source
A Stable Isopterin Mimic of a Potent Bacterial Stimulant of T Cells
A microbial metabolite covalently binds immunological protein MR1 to potently activate specific lymphocytes called MAIT cells, but it is too unstable for biological applications. Here, using synthesis, assays, protein crystallography, and computer modelling, we report a water‐stable analogue that activates reporter cells expressing the MAIT T cell ...
Jeffrey Y. W. Mak +9 more
wiley +1 more source
Geographical accessibility of cancer hospital using geospatial technology in Bagmati province, Nepal. [PDF]
Neupane BK +5 more
europepmc +1 more source
Nonafluoromesitylsulfonyl (Nms)‐substituted oxycarbamates are introduced as redox‐lowered radical precursors for green‐light photoredox synthesis. Selective N─O bond cleavage generates amidyl radicals that directly aminate indolizines in DMF, whereas DMSO promotes 1,2‐hydrogen atom transfer (HAT) to α‐amino carbon‐centered radicals and C─C bond ...
Kevin Klaus Stefanoni, René Wilhelm
wiley +1 more source

