ABSTRACT Background Chronic exposure to androgen receptor (AR)‐targeted therapies can drive lineage plasticity, leading to treatment resistance and neuroendocrine prostate cancer (NEPC), characterized by loss of AR expression and acquisition of neuroendocrine (NE) markers including synaptophysin (SYP). We evaluated concordance between circulating tumor
Ethan Lo +16 more
wiley +1 more source
Mediational role of metabolic syndrome between physical activity, sedentary behavior and non-alcoholic fatty liver disease: a cross-sectional study. [PDF]
Ren Z +9 more
europepmc +1 more source
Graphical representation of ethnomedical uses, major bioactive compounds, pharmacological potential and toxicological risks of Ruta graveolens L. ABSTRACT Ruta graveolens L. is widely used in traditional European, Asian, African, and South American medicine for digestive, nervous, cardiovascular, respiratory, and reproductive disorders.
Tetiana Serhiienko +3 more
wiley +1 more source
Optimal Exercise Modalities and Dosages for Blood Pressure Reduction in Adults With Prehypertension and Established Hypertension: A Network Meta-Analysis and Dose-Response Relationship Study. [PDF]
Xin X +5 more
europepmc +1 more source
Plant‐Derived Natural Product Nanodelivery System in Cancer Therapy
This review comprehensively summarizes the recent progress and emerging concepts in nanotechnology‐based delivery systems for plant‐derived natural products, with a particular focus on their application in precision cancer therapy. ABSTRACT Plant‐derived natural products have emerged as important sources of anticancer agents because of their diverse ...
Changqi Shi +9 more
wiley +1 more source
Commentary on: Intensity modifies the association between continuous bouts of physical activity and risk of mortality: A prospective UK Biobank cohort analysis. [PDF]
Ainsworth BE, Cai Z.
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Observer Design for Vector Nonlinear Systems With Applications to Autonomous Vehicles and Robots
ABSTRACT This paper focuses on observer design for nonlinear systems involving functions of vector arguments. The output equations and the process dynamics are both composed of nonlinear functions of nonseparable multivariable states. The partial derivatives of the nonlinear functions are assumed to be bounded.
Gaurav Sharma +2 more
wiley +1 more source
A prospective study of male physical activity and fecundability. [PDF]
Wise LA +11 more
europepmc +1 more source
ABSTRACT Social considerations are often overlooked in efforts to achieve sustainable development, despite being critical for building equitable and resilient global value chains. This study addresses this gap by applying a social life cycle assessment to three key Portuguese forest wood supply chains—uncoated woodfree paper, natural cork stoppers, and
Andreia Santos +3 more
wiley +1 more source
Effects of concurrent training on exercise capacity and quality of life in older adult patients with COPD: a Bayesian pairwise and dose-response meta-analysis. [PDF]
Li S, Yin Y, Guan J, Yu L.
europepmc +1 more source

